Results 141 to 150 of about 37,211,421 (159)

Cardiac G-Protein–Coupled Receptor Kinase 2 Ablation Induces a Novel Ca2+ Handling Phenotype Resistant to Adverse Alterations and Remodeling After Myocardial Infarction [PDF]

Circulation, 2012
G-protein-coupled receptor kinase 2 (GRK2) is a primary regulator of β-adrenergic signaling in the heart. G-protein-coupled receptor kinase 2 ablation impedes heart failure development, but elucidation of the cellular mechanisms has not been achieved ...
Steven R Houser, Philip Raake, Xiongwen Chen   +2 more
exaly   +2 more sources

Extracellular signal-regulated kinases control expression of G protein-coupled receptor kinase 2 (GRK2) [PDF]

FEBS Letters, 2002
G protein-coupled receptor kinase 2 (GRK2) phosphorylates G protein-coupled receptors resulting in uncoupling from G proteins. Receptors modulate GRK2 expression, however the mechanistic basis for this effect is largely unknown.
Juliane Theilade, Søren P Sheikh, Jakob L Hansen   +2 more
exaly   +2 more sources

G protein-coupled receptor kinase 2 (GRK2) is a Rho-activated scaffold protein for the ERK MAP kinase cascade [PDF]

Cellular Signalling, 2013
The G protein-coupled receptor kinases (GRKs) are best known for their role in phosphorylating and desensitising G protein-coupled receptors (GPCRs). The GRKs also regulate signalling downstream of other families of receptors and have a number of non ...
Julie A Pitcher
exaly   +2 more sources

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Protein expression and purification of G-protein coupled receptor kinase 6 (GRK6), toward structure-based drug design and discovery for multiple myeloma

Protein Expression and Purification, 2021
Shangji Zhang, Nathalie Meurice, Emily Kaschner   +2 more
exaly  

G-Protein–Coupled Receptor Kinase Interacting Protein-1 Is Required for Pulmonary Vascular Development

Circulation, 2009
Michael Massett, Jinjiang Pang, Chen Yan
exaly  

Prodeath Signaling of G Protein–Coupled Receptor Kinase 2 in Cardiac Myocytes After Ischemic Stress Occurs Via Extracellular Signal–Regulated Kinase-Dependent Heat Shock Protein 90–Mediated Mitochondrial Targeting

Circulation Research, 2013
Jessica Ibetti, Erhe Gao, Shi Pan
exaly  

Dopamine and G protein-coupled receptor kinase 4 in the kidney: Role in blood pressure regulation

Biochimica Et Biophysica Acta - Molecular Basis of Disease, 2010
Patrício Soares-da-Silva, Pedro A. Jose, Robin A Felder   +2 more
exaly  

The subcellular and cellular distribution of G protein-coupled receptor kinase 2 in rat brain

Neuroscience, 1998
Cristina Murga, Federico Mayor Menéndez, Francisco Zafra   +2 more
exaly  

Purification, crystallization and preliminary X-ray diffraction studies of a complex between G protein-coupled receptor kinase 2 and Gβ1γ2

Acta Crystallographica Section D: Biological Crystallography, 2003
John Tesmer, Julie A Pitcher
exaly  

Regulation of G protein-coupled receptor kinase subtypes by calcium sensor proteins

Biochimica Et Biophysica Acta - Molecular Cell Research, 2000
Michele Sallese, Loredana Capobianco, Luisa Iacovelli   +2 more
exaly