Structural insights into Phospholipase Cε activity and regulation. [PDF]
Mahurkar KA +3 more
europepmc +1 more source
Unraveling the RKIP-YY1 axis: immune crosstalk in the pathogenesis of metabolic disorders. [PDF]
Alzaid F +9 more
europepmc +1 more source
Protein Kinases as Mediators for miRNA Modulation of Neuropathic Pain. [PDF]
Chang L, Čok Z, Yu L.
europepmc +1 more source
Canonical or non-canonical, all aspects of G protein-coupled receptor kinase 2 in heart failure. [PDF]
Kaplan A +5 more
europepmc +1 more source
GRK2 and Mitochondrial Dynamics in Cardiovascular Health and Disease. [PDF]
Gatto C +3 more
europepmc +1 more source
Distinct Phosphorylation Patterns of AT1R by Biased Ligands and GRK Subtypes. [PDF]
Zhang Z +6 more
europepmc +1 more source
Drug Repositioning in Doxorubicin-Induced Cardiotoxicity Protection. [PDF]
Kosić M +3 more
europepmc +1 more source
Serotonin 5-HT<sub>2C</sub> Receptor Signaling Analysis Reveals Psychedelic Biased Agonism. [PDF]
Bonniwell EM +9 more
europepmc +1 more source
G protein-coupled receptor kinase 2 (GRK2): mechanisms of regulation and physiological functions [PDF]
G protein‐coupled receptor kinase 2 (GRK2) plays a key role in determining the rate and extent of G protein‐coupled receptor (GPCR) desensitization and resensitization. Recent data indicate that GRK2 activity, subcellular distribution and expression are tightly regulated.
Anna M Aragay, Federico Mayor
exaly +3 more sources
Extracellular signal-regulated kinases control expression of G protein-coupled receptor kinase 2 (GRK2) [PDF]
G protein‐coupled receptor kinase 2 (GRK2) phosphorylates G protein‐coupled receptors resulting in uncoupling from G proteins. Receptors modulate GRK2 expression, however the mechanistic basis for this effect is largely unknown. Here we report a novel mechanism by which receptors use the extracellular signal‐regulated kinase (ERK) cascade to regulate ...
Juliane Theilade
exaly +3 more sources

