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The versatile GABA in plants [PDF]
Plant Signaling & Behavior, 2021 Gamma-aminobutyric acid (GABA) is a ubiquitous four-carbon, non-protein amino acid. GABA has been widely studied in animal central nervous systems, where it acts as an inhibitory neurotransmitter. In plants, it is metabolized through the GABA shunt pathway, a bypass of the tricarboxylic acid (TCA) cycle.
Li Li, Na Dou, Hui Zhang, Chunxia Wu
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Antinociceptive and anti-inflammatory effect of a standardized fraction of Oenothera rosea L'Hér. ex Aiton and its possible mechanism of action in mice [PDF]
Avicenna Journal of Phytomedicine, 2022 Objective: This study was conducted to investigate the antinociceptive and anti-inflammatory effect of ethyl acetate fraction of Oenothera rosea (EAOr) and the mechanism involved, in mice.Materials and Methods: The antinociceptive activity was tested ...
Rodrigo Vargas-Ruiz +6 more
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Shipin gongye ke-ji, 2023 Objective: To study the sleep-improving effect of Ziziphi spinosae Semen Poria cocos powder and soybean peptide powder on insomnia model mice induced by p-chlorophenylalanine (PCPA). Methods: One hundred eighty SPF male BALB/c mice were purchased. First,
Rong WEI +4 more
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Open Life Sciences, 2023 In addition to the known metabolic alterations, obesity has consequences at the brain level, driving imbalance in neurotransmitters such as glutamate (Glu), glutamine (Gln), and gamma-aminobutyric acid (GABA).
Sandoval-Salazar Cuauhtémoc +4 more
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Frontiers in Immunology, 2022 Gamma-aminobutyric acid (GABA) and GABA-receptors (GABA-Rs) form a major neurotransmitter system in the brain. GABA-Rs are also expressed by 1) cells of the innate and adaptive immune system and act to inhibit their inflammatory activities, and 2) lung ...
Jide Tian +4 more
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Psychobiotics – Probiotics that Improve Mood
Harčova Nauka ì Tehnologìâ, 2021 The human intestinal microbiome includes all microorganisms inhabiting the intestinal tract. One study showed that mice raised in a sterile environment exhibited excessive physiological responses to stress compared to normal control.
L. Kapreliants, E Zhuk
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Gamma-hydroxybutyrate abuse: pharmacology and poisoning and withdrawal management
Arhiv za Higijenu Rada i Toksikologiju, 2020 Gamma-hydroxybutyrate (GHB) is a central nervous system depressant primarily used as a recreational drug of abuse, but also for the treatment of narcolepsy with cataplexy in adult patients and as an adjuvant for control of alcohol withdrawal syndrome ...
Marinelli Enrico +4 more
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Extrasynaptic δ-subunit containing GABAA receptors [PDF]
Journal of Integrative Neuroscience, 2021 γ-Aminobutyric acid type A receptors (GABAARs) are GABA gated heteropentameric chloride channels responsible for the adult brain’s primary inhibition.
Ayla Arslan
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Investigation on Hypothalamic GABAergic system difference of local and Leghorn hens based on RNA-Seq dataset [PDF]
مجله بیوتکنولوژی کشاورزی, 2023 Objective: g-Aminobutyric acid (GABA) is a non-protein amino acid synthesized by decarboxylation of glutamate by the enzyme glutamic acid decarboxylase. The central nervous system (CNS) contains uniquely high concentrations of GABA, and GABA serves as a ...
Yadollah Badakhshan +2 more
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WormBook, 2005 The most abundant synapses in the central nervous system of vertebrates are inhibitory synapses that use the neurotransmitter gamma-aminobutyric acid (GABA). GABA is also an important neurotransmitter in C. elegans; however, in contrast to vertebrates where GABA acts at synapses of the central nervous system, in nematodes GABA acts primarily at ...
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