Results 181 to 190 of about 105,256 (293)

Structural basis for activation and potentiation in a human α5β3 GABA A receptor

open access: gold
John Cowgill   +4 more
openalex   +1 more source

Specific targeting of the GABA-A receptor α5 subtype by a selective inverse agonist restores cognitive deficits in Down syndrome mice

open access: hybrid, 2011
Jérôme Braudeau   +9 more
openalex   +1 more source

Convergence Deficits in Myoclonus‐Dystonia Point to Cerebellar Impairment

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Myoclonus‐dystonia (M‐D) is a monogenic movement disorder, with proposed cerebellar dysfunction. Vergence eye movement deficits, characteristics of degenerative cerebellar disease, have not been studied in M‐D. Cerebellar transcranial alternating current stimulation (tACS) is considered a potential therapeutic approach.
Skadi Gerkensmeier   +13 more
wiley   +1 more source

GABA-ρ receptors: distinctive functions and molecular pharmacology. [PDF]

open access: yesBr J Pharmacol, 2017
Naffaa MM   +4 more
europepmc   +1 more source

Morphological Changes in Direct Pathway Striatal Neurons in a Rat Model of Tardive Dyskinesia

open access: yesMovement Disorders, EarlyView.
Abstract Background Tardive dyskinesia (TD) and drug‐induced parkinsonism (DIP) arise from prolonged dopamine antagonist use. Although D2 receptor hypersensitivity in the indirect pathway is a proposed mechanism, the role of the direct pathway remains unclear.
Hiroki Hikichi   +6 more
wiley   +1 more source

Light‐Based Molecular Tools to Precisely Monitor and Operate β‐Adrenoceptors

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT β‐Adrenoceptors are important G protein–coupled receptors involved in cardiovascular, metabolic, and neurological regulation. To study their function with high precision, light‐based molecular tools have been developed offering precise spatiotemporal control.
Ignazzitto Maria Tindara   +3 more
wiley   +1 more source

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