Results 191 to 200 of about 101,312 (260)

GABA_A receptor agonists modulate intracellular Ca²⁺ levels in activated human CD4⁺ T cells. [PDF]

Front Immunol
Korol SV, Jin Z, Bhandage AK, Hammoud H, Birnir B.   +4 more
europepmc   +1 more source

Gold‐standard evidence and best practice guidance for menstrual cycle‐informed clinical care: An overview for clinicians

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives To synthesize current evidence and provide clinically actionable recommendations for integrating menstrual cycle‐related processes—particularly hormone sensitivity, Premenstrual Dysphoric Disorder (PMDD) and Premenstrual Exacerbation (PME)—into psychological assessment, formulation and treatment.
Ellen R. Lambert, Louise N. Nolan, Katja M. Schmalenberger   +2 more
wiley   +1 more source

Structural basis for activation and potentiation in a human α5β3 GABA_A receptor. [PDF]

Nat Commun
Cowgill J, Fan C, Steyaert J, Howard RJ, Lindahl E.   +4 more
europepmc   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Precision phenotyping of elevated arousal in posttraumatic stress disorder: implications for personalized GABAergic pharmacotherapy. [PDF]

Front Psychiatry
Vasquez VR, Howlett JR.
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Pharmacological principles for safe benzodiazepine and Z-drug dose reduction. [PDF]

Psychol Med
Horowitz M, Lamberson N, Brandt J, Framer A, Shapiro B, Sørensen A, Cadogan C, Ritvo A, Taylor D.   +8 more
europepmc   +1 more source

Molecular and neural circuit mechanisms of parvalbumin (PV) neurons in depression: Insights and advances. [PDF]

iScience
Li ZX, Si TE, Wu QR, Zhao JH, Hua WZ, Zhang YY, Yang S, Mao YY, Zang WD, Cao J.   +9 more
europepmc   +1 more source

Neurotransmitter-Mediated Signaling in Glioblastoma and Glial Tumors: Biology and Therapeutic Opportunities. [PDF]

Oncol Res
Tralongo P, Ballato M, Zuccalà V, Fiorentino V, Giordano W, Casili G, Bellinghieri F, Caruso G, Angileri FF, Fadda G, Martini M, Caffo M.   +11 more
europepmc   +1 more source

Artificial intelligence in the assessment of epilepsy-related genetic mutations: Learned from GABA_A receptors and GABA transporter 1. [PDF]

Epilepsia Open
Wang J, Kang JQ.
europepmc   +1 more source