Results 151 to 160 of about 258,602 (310)

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Requirement for CB1 but not GABA_B receptors in the cholecystokinin mediated inhibition of GABA release from cholecystokinin expressing basket cells

, 2010
Sang‐Hun Lee, Iván Soltész
openalex   +2 more sources

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

Seizures beget more than seizures: Understanding the cellular, structural, individual and societal impact of seizures in epilepsy

Epilepsia Open, EarlyView.
Abstract Epilepsy is primarily defined by the repetitive occurrence of seizures, but the full impact of seizures extends beyond these episodic events. Seizures themselves cause changes at the cellular, network, and systemic levels in individual patients with epilepsy and may contribute to the progressive nature of the disease in some patients. Seizures
Matthew C. Walker, Marian Galovic, Elena Álvarez‐Barón, Adam Strzelczyk   +3 more
wiley   +1 more source

The effects of stiripentol on GABA_A receptors [PDF]

, 2011
Janet L. Fisher
openalex   +1 more source

Low Dopamine D2 Receptor Expression Drives Gene Networks Related to GABA, cAMP, Growth and Neuroinflammation in Striatal Indirect Pathway Neurons

, 2022
Lucía Guerri, Lauren K. Dobbs, Daniel Almeida da Silva e Silva, Allen Meyers, Aaron Ge, Lea Lecaj, Caroline Djakuduel, Damien Islek, Dionisio Hipolito, Abdiel Badillo-Martinez, Pei‐Hong Shen, Cheryl A. Marietta, Susanna P. Garamszegi, Enrico Capobianco, Zhijie Jiang, Melanie L. Schwandt, Deborah C. Mash, Veronica A. Alvarez, David Goldman   +18 more
openalex   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Reductions in rostral anterior cingulate GABA are associated with stress circuitry in females with major depression: a multimodal imaging investigation [PDF]

, 2021
Maria Ironside, Amelia D. Moser, Laura M. Holsen, Chun S. Zuo, Fei Du, Sarah Perlo, Christine E. Richards, Jessica M. Duda, Xi Chen, Lisa D. Nickerson, Kaylee E. Null, Nara F. Nascimento, David J. Crowley, Madhusmita Misra, Jill M. Goldstein, Diego A. Pizzagalli   +15 more
openalex   +1 more source

Adjunctive acetazolamide for drug‐resistant seizures in SLC6A1‐related neurodevelopmental disorder: An exploratory case series

Epilepsia Open, EarlyView.
Abstract Pathogenic variants in SLC6A1 cause a neurodevelopmental disorder characterized by developmental delay with behavioral disturbances, seizures, often pharmacoresistant, and a spectrum of movement disorders such as ataxia. A similar triad is observed in other monogenic conditions, such as SLC2A1, CHD2, and CACNA1A‐related disorders, where ...
Gia Melikishvili, Olivier Dulac, Otar Koniashvili, Giorgi Mamardashvili, Tamar Gachechiladze, Nazhi Tabatadze, Mariam Melikishvili, Rimma Gamirova, Tatyana Tomenko, Igor Bakhtin, Amber Freed, Elena Bossi, Bruria Ben‐Zeev, Gerhard Kluger, Antonio Falace, Antonella Riva, Kai Kaila, Pasquale Striano   +17 more
wiley   +1 more source

Transcriptomic and spatial organization of telencephalic GABAergic neurons. [PDF]

Nature
van Velthoven CTJ, Gao Y, Kunst M, Lee C, McMillen D, Chakka AB, Casper T, Clark M, Chakrabarty R, Daniel S, Dolbeare T, Ferrer R, Gloe J, Goldy J, Guzman J, Halterman C, Ho W, Huang MJ, James K, McCue R, Nguy B, Cardenas T, Ronellenfitch K, Thomas ED, Torkelson A, Pagan CM, Kruse L, Dee N, Ng L, Waters J, Smith KA, Tasic B, Yao Z, Zeng H.   +33 more
europepmc   +1 more source