Results 181 to 190 of about 343,837 (291)

Modular Model of Neuronal Activity That Captures the Dynamics of Main Molecular Targets of Antiepileptic Drugs. [PDF]

Int J Mol Sci
Kondrakhin PY, Kolpakov FA.
europepmc   +1 more source

Light‐Based Molecular Tools to Precisely Monitor and Operate β‐Adrenoceptors

Medicinal Research Reviews, EarlyView.
ABSTRACT β‐Adrenoceptors are important G protein–coupled receptors involved in cardiovascular, metabolic, and neurological regulation. To study their function with high precision, light‐based molecular tools have been developed offering precise spatiotemporal control.
Ignazzitto Maria Tindara, Gómez‐Santacana Xavier, Llebaria Amadeu, Rovira Xavier   +3 more
wiley   +1 more source

Comparison of neuro-metabolites in borderline and antisocial personality disorders: A study based on proton magnetic resonance spectroscopy. [PDF]

Personal Neurosci
Asgari Ghalebin SS, Bashrpour S, Mikaeili N, Hajloo N, Gholipour F.   +4 more
europepmc   +1 more source

Identifying Out‐of‐Voxel Echoes in Edited MRS With Phase Cycle Inversion

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To identify the origin of out‐of‐voxel (OOV) signals based on the coherence transfer pathway (CTP) formalism using signal phase conferred by the acquisition phase cycling scheme. Knowing the CTP driving OOV artifacts enables optimization of crusher gradients to improve their suppression.
Zahra Shams, Abdelrahman Gad, Aaron T. Gudmundson, Saipavitra Murali‐Manohar, Christopher W. Davies‐Jenkins, Gizeaddis L. Simegn, Dunja Simicic, Yulu Song, Vivek Yedavalli, Helge J. Zöllner, Georg Oeltzschner, Dillip K. Senapati, Alfons Schnitzler, Peter B. Barker, Richard A. E. Edden   +14 more
wiley   +1 more source

Tonic GABA_A receptor currents in Cerebellar Purkinje cells of wild-type and DMD^mdx mice. [PDF]

Sci Rep
Mitra S, Khatri SN, Pugh JR.
europepmc   +1 more source

Simultaneous Detection of GABA and Glycine Using MEGA‐PRESS With TE Optimization at 3T

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To achieve the simultaneous acquisition of gamma‐aminobutyric acid (GABA) and glycine (Gly) using a MEGA‐PRESS sequence with an optimized TE at 3T. Methods MEGA‐PRESS simulations were performed at TEs 60‐88 ms to determine the optimal TE for Gly detection with minimal myo‐Inositol (mI) overlap and maximal GABA detection sensitivity ...
Justin R. Singer, Kimberly L. Chan
wiley   +1 more source

Guanidino compounds with native GABA(A) δ receptor selectivity: a tale of homeostatic compensation in δ-KO mice. [PDF]

BMC Neurosci
Meera P, Uusi-Oukari M, Wallner M, Lipshutz GS.   +3 more
europepmc   +1 more source

Inter‐Individual Differences in T1, T2, and Proton Density Using Quantitative Synthetic Imaging for 1H‐MRS Quantification

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Metabolite concentrations can be determined from proton magnetic resonance spectroscopy (1H‐MRS) data using water as an internal reference. This calculation requires tissue‐specific water T1 and T2 relaxation constants and proton density (PD).
Samantha A. Leech, Sarah L. Manske, Paul G. Mullins, Tiffany K. Bell, Ashley D. Harris   +4 more
wiley   +1 more source

Biochar and γ-Aminobutyric acid partnership improves rice productivity and mitigates Sb + Pb toxicity in co-contaminated soil. [PDF]

BMC Plant Biol
Aamer M, Zhang J, Awan MI, Wei H, Nabi F, Huang W, Liu Z, Su X, Liu S, Elnour RO, Hashem M.   +10 more
europepmc   +1 more source

Modifying Antibiotic Activity of Synthetic Thiadiazine Analogs Against MDR Bacteria and ADMET Analysis

ChemistryOpen, EarlyView.
The study demonstrated that thidiazine compounds potentiated the action of antibiotics. The compounds associated with norfloxacin against S. aureus showed greater significance in relation to the other medications. The indiscriminate use of antibiotics has led to the selection of resistant bacterial strains, significantly reducing the effectiveness of ...
João Arthur de Oliveira Borges, Priscilla Ramos Freitas, Isaac Moura Araújo, Ray Silva de Almeida, Igor José dos Santos Nascimento, João Xavier de Araújo‐Júnior, Edeildo Ferreira da Silva‐Júnior, Thiago Mendonça de Aquino, Francisco Jaime Bezerra Mendonça Junior, Emmanuel Silva Marinho, Hélcio Silva dos Santos, Radosław Kowalski, Grażyna Kowalska, Henrique Douglas Melo Coutinho, Saulo Relison Tintino, Ana Carolina Justino de Araújo   +15 more
wiley   +1 more source