Results 11 to 20 of about 245,202 (346)

B cell-derived GABA elicits IL-10+ macrophages to limit anti-tumour immunity

open access: yesNature, 2021
Small, soluble metabolites not only are essential intermediates in intracellular biochemical processes, but can also influence neighbouring cells when released into the extracellular milieu1–3. Here we identify the metabolite and neurotransmitter GABA as
Baihao Zhang   +29 more
semanticscholar   +1 more source

GABA signalling modulates stomatal opening to enhance plant water use efficiency and drought resilience

open access: yesNature Communications, 2021
The non-protein amino acid γ-aminobutyric acid (GABA) has been proposed to be an ancient messenger for cellular communication conserved across biological kingdoms.
Bo Xu   +11 more
semanticscholar   +1 more source

GABA Production by Human Intestinal Bacteroides spp.: Prevalence, Regulation, and Role in Acid Stress Tolerance

open access: yesFrontiers in Microbiology, 2021
The high neuroactive potential of metabolites produced by gut microbes has gained traction over the last few years, with metagenomic-based studies suggesting an important role of microbiota-derived γ-aminobutyric acid (GABA) in modulating mental health ...
Nize Otaru   +10 more
semanticscholar   +1 more source

GABA: A Key Player in Drought Stress Resistance in Plants

open access: yesInternational Journal of Molecular Sciences, 2021
γ-aminobutyric acid (GABA) is a non-protein amino acid involved in various physiological processes; it aids in the protection of plants against abiotic stresses, such as drought, heavy metals, and salinity.
M. Hasan   +10 more
semanticscholar   +1 more source

United States Pharmacopeia (USP) Safety Review of Gamma-Aminobutyric Acid (GABA)

open access: yesNutrients, 2021
Gamma-amino butyric acid (GABA) is marketed in the U.S. as a dietary supplement. USP conducted a comprehensive safety evaluation of GABA by assessing clinical studies, adverse event information, and toxicology data.
H. Oketch-Rabah   +3 more
semanticscholar   +1 more source

Bifidobacterium adolescentis as a key member of the human gut microbiota in the production of GABA

open access: yesScientific Reports, 2020
Gamma aminobutyric acid (GABA) is the principal inhibitory neurotransmitter playing a key role in anxiety and depression disorders in mammals. Recent studies revealed that members of the gut microbiota are able to produce GABA modulating the gut–brain ...
S. Duranti   +13 more
semanticscholar   +1 more source

Phenotype Expression Variability in Children with GABRB3 Heterozygous Mutations

open access: yesOman Medical Journal, 2021
GABRB3 gene is a recently identified gene located in 15q12 chromosome and encodes for gamma-aminobutyric acid (GABA) receptor subunit beta-3 protein, which is linked to the GABAA receptor.
Abdulhafeez M. Khair, Alana E. Salvucci
doaj   +1 more source

Effects of Oral Gamma-Aminobutyric Acid (GABA) Administration on Stress and Sleep in Humans: A Systematic Review

open access: yesFrontiers in Neuroscience, 2020
Gamma-aminobutyric acid (GABA) is a non-proteinogenic amino acid and is the main inhibitory neurotransmitter in the mammalian brain. GABA's stress-reducing, and sleep enhancing effects have been established.
P. Hepsomali   +3 more
semanticscholar   +1 more source

Mesencephalic GABA neuronal development: no more on the other side of oblivion

open access: yesBiomolecular Concepts, 2014
Midbrain GABA neurons, endowed with multiple morphological, physiological and molecular characteristics as well as projection patterns are key players interacting with diverse regions of the brain and capable of modulating several aspects of behavior ...
Li Suyan, Joshee Sampada, Vasudevan Anju
doaj   +1 more source

Chasing after minerality, relationship to yeasts nutritional stress and succinic acid production

open access: yesCzech Journal of Food Sciences, 2012
Minerality is certainly one of the most mysterious and most valuable tones of wine taste and it is very often associated with the concept of terroir. The isotachophoresis was used for determination of cations - minerals in two wines from vineyards with ...
Mojmír Baroň, Jaromír Fiala
doaj   +1 more source

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