Results 11 to 20 of about 163,092 (297)
The versatile GABA in plants [PDF]
Plant Signaling & Behavior, 2021 Gamma-aminobutyric acid (GABA) is a ubiquitous four-carbon, non-protein amino acid. GABA has been widely studied in animal central nervous systems, where it acts as an inhibitory neurotransmitter. In plants, it is metabolized through the GABA shunt pathway, a bypass of the tricarboxylic acid (TCA) cycle.
Li Li, Na Dou, Hui Zhang, Chunxia Wu
openaire +3 more sources
WormBook, 2005 The most abundant synapses in the central nervous system of vertebrates are inhibitory synapses that use the neurotransmitter gamma-aminobutyric acid (GABA). GABA is also an important neurotransmitter in C. elegans; however, in contrast to vertebrates where GABA acts at synapses of the central nervous system, in nematodes GABA acts primarily at ...
openaire +2 more sources
Mesencephalic GABA neuronal development: no more on the other side of oblivion
Biomolecular Concepts, 2014 Midbrain GABA neurons, endowed with multiple morphological, physiological and molecular characteristics as well as projection patterns are key players interacting with diverse regions of the brain and capable of modulating several aspects of behavior ...
Li Suyan, Joshee Sampada, Vasudevan Anju
doaj +1 more source
Chasing after minerality, relationship to yeasts nutritional stress and succinic acid production
Czech Journal of Food Sciences, 2012 Minerality is certainly one of the most mysterious and most valuable tones of wine taste and it is very often associated with the concept of terroir. The isotachophoresis was used for determination of cations - minerals in two wines from vineyards with ...
Mojmír Baroň, Jaromír Fiala
doaj +1 more source
GABA as a rising gliotransmitter [PDF]
Frontiers in Neural Circuits, 2014 Gamma-amino butyric acid (GABA) is the major inhibitory neurotransmitter that is known to be synthesized and released from GABAergic neurons in the brain. However, recent studies have shown that not only neurons but also astrocytes contain a considerable amount of GABA that can be released and activate GABA receptors in neighboring neurons.
C. Justin Lee, Bo-Eun Yoon
openaire +4 more sources
L-655,708 does not prevent isoflurane-induced memory deficits in old mice
Translational Neuroscience, 2019 General anesthesia and increasing age are two main risk factors for postoperative cognitive dysfunction (POCD). Effective agents for the prevention or treatment of POCD are urgently needed.
Gao Teng +6 more
doaj +1 more source
Pharmaceuticals, 2019 Lurasidone is an atypical mood-stabilizing antipsychotic agent with unique receptor-binding profile, including 5-HT7 receptor (5-HT7R) antagonism. Effects of 5-HT7R antagonism on transmitter systems of schizophrenia and mood disorders, however, have not ...
Motohiro Okada +4 more
doaj +1 more source
Disease Models & Mechanisms, 2019 Epilepsy is a common primary neurological disorder characterized by the chronic tendency of a patient to experience epileptic seizures, which are abnormal body movements or cognitive states that result from excessive, hypersynchronous brain activity ...
Meijiang Liao +7 more
doaj +1 more source
Investigation of the Effect of Anakinra on Pentylenetetrazole-Induced Epileptic Seizures in Mice
Ahi Evran Medical Journal, 2021 Purpose: Disruption of the balance between gamma aminobutyric acid (GABA) and glutamate in the brain is one of the important factors contributing to seizure formation and epileptogenesis.
Ahmet Kemal FİLİZ +1 more
doaj +1 more source
GABA Generates Excitement [PDF]
Neuron, 2003 In the CNS, gamma-aminobutyric acid (GABA) acts as an inhibitory transmitter via ligand-gated GABA(A) receptor channels and G protein-coupled GABA(B) receptors. Both of these receptor types mediate inhibitory postsynaptic transmission throughout the nervous system. For GABA(A) receptors, this inhibitory action is associated with a hyperpolarization due
Roger A. Nicoll, Valentin Stein
openaire +3 more sources