Results 21 to 30 of about 333,224 (356)
Gamma-hydroxybutyrate abuse: pharmacology and poisoning and withdrawal management
Arhiv za Higijenu Rada i Toksikologiju, 2020 Gamma-hydroxybutyrate (GHB) is a central nervous system depressant primarily used as a recreational drug of abuse, but also for the treatment of narcolepsy with cataplexy in adult patients and as an adjuvant for control of alcohol withdrawal syndrome ...
Marinelli Enrico +4 more
doaj +1 more source
Insights into GABA receptor signalling in TM3 Leydig cells [PDF]
, 2005 gamma-Aminobutyric acid (GABA) is an emerging signalling molecule in endocrine organs, since it is produced by endocrine cells and acts via GABA(A) receptors in a paracrine/autocrine fashion.
Artur Mayerhofer +28 more
core +2 more sources
Disease Models & Mechanisms, 2019 Epilepsy is a common primary neurological disorder characterized by the chronic tendency of a patient to experience epileptic seizures, which are abnormal body movements or cognitive states that result from excessive, hypersynchronous brain activity ...
Meijiang Liao +7 more
doaj +1 more source
Synaptic GABA release prevents GABA transporter type-1 reversal during excessive network activity. [PDF]
, 2015 GABA transporters control extracellular GABA, which regulates the key aspects of neuronal and network behaviour. A prevailing view is that modest neuronal depolarization results in GABA transporter type-1 (GAT-1) reversal causing non-vesicular GABA ...
Megalogeni, M +4 more
core +1 more source
Indian Journal of Neurosurgery, 2013 Investigating the changes associated with the development of epileptic state in humans is complex and requires a multidisciplinary approach. Understanding the intricacies of medically intractable epilepsy still remains a challenge for neurosurgeons ...
Jyotirmoy Banerjee +2 more
doaj +1 more source
Functional connectivity in behavioral variant frontotemporal dementia
Brain and Behavior, Volume 12, Issue 12, December 2022., 2022 Decreased FC in the Salience Network (SN) is the most consistent finding in bvFTD. The brain's functional architecture is less interconnected and efficient in bvFTD. Symptom, behavior, cognition and disease severity are associated with changes in FC. Abstract Introduction Functional connectivity (FC)—which reflects relationships between neural activity
Luiz Kobuti Ferreira +3 more
wiley +1 more source
Pharmaceuticals, 2019 Lurasidone is an atypical mood-stabilizing antipsychotic agent with unique receptor-binding profile, including 5-HT7 receptor (5-HT7R) antagonism. Effects of 5-HT7R antagonism on transmitter systems of schizophrenia and mood disorders, however, have not ...
Motohiro Okada +4 more
doaj +1 more source
Sheep’s milk cheeses as a source of bioactive compounds
Acta Universitatis Cibiniensis. Series E: Food Technology, 2021 Since ancient times, sheep`s milk cheeses have been a part of a human diet. Currently, their consumption is of great interest due to its nutritional and health values.
Skotniczny Magdalena, Satora Paweł
doaj +1 more source
GABA as a rising gliotransmitter [PDF]
Frontiers in Neural Circuits, 2014 Gamma-amino butyric acid (GABA) is the major inhibitory neurotransmitter that is known to be synthesized and released from GABAergic neurons in the brain. However, recent studies have shown that not only neurons but also astrocytes contain a considerable amount of GABA that can be released and activate GABA receptors in neighboring neurons.
C. Justin Lee, Bo-Eun Yoon
openaire +4 more sources
Regulation of Arabidopsis 14-3-3 gene expression by GABA. [PDF]
, 2006 The function in plants of the non-protein amino acid, gamma-aminobutyric acid (GABA) is poorly understood. In this study, we show that GABA down-regulates the expression of a large sub-set of 14-3-3 gene family members in Arabidopsis thaliana seedlings ...
Lancien, Muriel, Roberts, Michael R
core +1 more source