Results 21 to 30 of about 163,092 (297)

Flumazenil Pretreatment Reduces Mefenamic Acid-Induced Central Nervous System Toxicity in Mice

Journal of Integrative Neuroscience, 2023
Background: Mefenamic acid (MFA), a common analgesic, causes central nervous system (CNS) toxicity at high doses with a proposed activity on the Gamma-aminobutyric acid (GABA) system.
Qais Jarrar, Rami Ayoub, Yazun Jarrar, Hadeel Aburass, Khang Wen Goh, Chrismawan Ardianto, Long Chiau Ming, Said Moshawih, Hussain Alfaqih   +8 more
doaj   +1 more source

GABA and mood disorders [PDF]

Psychological Medicine, 2003
A γ-aminobutyric acid (GABA)-ergic theory of mood disorders was proposed by Emrich and colleagues (1980) following observations of the efficacy of the GABAergic anticonvulsant, valproate, in the treatment of mania. Since then, increasing biochemical and pharmacological evidence from animal and human studies has supported the hypothesis that mood ...
Taylor, MJ, Bhagwagar, Z, Cowen, PJ, Sharp, T   +3 more
openaire   +6 more sources

Characterization of GABA Receptors [PDF]

Current Protocols in Pharmacology, 1998
AbstractDescribed in this unit are ligand‐binding assays for GABAA, GABAB, and the homomeric ρ GABAA(formerly GABAC) receptor recognition sites in brain tissue. Although GABA binding sites are present in peripheral organs, most research is directed toward examining these receptors in the CNS.
Kenneth E. McCarson, S.J. Enna
openaire   +2 more sources

Astrocyte-Ablation of Mtnr1b Increases Anxiety-Like Behavior in Adult Male Mice

Journal of Integrative Neuroscience, 2023
Background: Astrocytes are essential for synaptic transmission, and their dysfunction can result in neuropsychiatric disorders such as anxiety and depression.
Zijun Meng, Shipeng Guo, Xiangjun Dong, Qunxian Wang, Dongjie Hu, Xiaoqi Liu, Yanshuang Jiang, Liangye Ji, Jie Zhang, Weiyi Zhu, Weihui Zhou, Weihong Song   +11 more
doaj   +1 more source

A companion to the preclinical common data elements and case report forms for neuropathology studies in epilepsy research. A report of the TASK3 WG2 Neuropathology Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica, Devin K. Binder, Meinrad Drexel, Chrysanthy Ikonomidou, Shilpa D. Kadam, Guenther Sperk, Christian Steinhäuser   +6 more
wiley   +1 more source

A companion to the preclinical common data elements and case report forms for in vivo rodent neuroimaging: A report of the TASK3‐WG3 Neuroimaging Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Erwin A. van Vliet, Riikka Immonen, Ofer Prager, Alon Friedman, Jens P. Bankstahl, David K. Wright, Terence J. O'Brien, Heidrun Potschka, Olli Gröhn, Neil G. Harris   +9 more
wiley   +1 more source

Effectiveness of germinated brown rice on metabolic syndrome: A randomized control trial in Vietnam

AIMS Public Health, 2020
To treating Metabolic Syndrome (MetS) in the human body by using cooked pre- germinated brown rice (PGBR), a randomized control trial was done in Vietnam. 80 subjects (65.1 ± 3.81 years old) separated into two groups in pairs were assigned a daily intake
Truong Tuyet Mai, Tran Thu Trang, Tran Thi Hai   +2 more
doaj   +1 more source

sleep disorders due to neuroinfections: clinical symptoms, neurochemistry and neurophysiology V.B. Voitenkov1, N.V. Skripchenko1, Y.E. Zueva 2

Журнал инфектологии, 2015
In our review we present data on sleep disturbances in neuroinfections (encephalitis and meningitis), their clinical signs, neurochemistry and neurophysiology.
V. B. Voitenkov, N. V. Skripchenko, Y. E. Zueva   +2 more
doaj   +1 more source

Identification of Novel Prognostic Biomarkers That are Associated with Immune Microenvironment Based on GABA-Related Molecular Subtypes in Gastric Cancer

Pharmacogenomics and Personalized Medicine, 2023
Beibei Wang, Linlin Huang, Shanliang Ye, Zhongwen Zheng, Shanying Liao Department of Gastroenterology and Hepatology, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, 510080, People’s Republic of ...
Wang B, Huang L, Ye S, Zheng Z, Liao S
doaj  

Understanding complexities of synaptic transmission in medically intractable seizures: A paradigm of epilepsy research

Indian Journal of Neurosurgery, 2013
Investigating the changes associated with the development of epileptic state in humans is complex and requires a multidisciplinary approach. Understanding the intricacies of medically intractable epilepsy still remains a challenge for neurosurgeons ...
Jyotirmoy Banerjee, Manjari Tripathi, P. Sarat Chandra   +2 more
doaj   +1 more source