Results 21 to 30 of about 343,837 (291)
Disease Models & Mechanisms, 2019 Epilepsy is a common primary neurological disorder characterized by the chronic tendency of a patient to experience epileptic seizures, which are abnormal body movements or cognitive states that result from excessive, hypersynchronous brain activity ...
Meijiang Liao +7 more
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L-655,708 does not prevent isoflurane-induced memory deficits in old mice
Translational Neuroscience, 2019 General anesthesia and increasing age are two main risk factors for postoperative cognitive dysfunction (POCD). Effective agents for the prevention or treatment of POCD are urgently needed.
Gao Teng +6 more
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Pharmaceuticals, 2019 Lurasidone is an atypical mood-stabilizing antipsychotic agent with unique receptor-binding profile, including 5-HT7 receptor (5-HT7R) antagonism. Effects of 5-HT7R antagonism on transmitter systems of schizophrenia and mood disorders, however, have not ...
Motohiro Okada +4 more
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Investigation on Hypothalamic GABAergic system difference of local and Leghorn hens based on RNA-Seq dataset [PDF]
مجله بیوتکنولوژی کشاورزی, 2023 Objective: g-Aminobutyric acid (GABA) is a non-protein amino acid synthesized by decarboxylation of glutamate by the enzyme glutamic acid decarboxylase. The central nervous system (CNS) contains uniquely high concentrations of GABA, and GABA serves as a ...
Yadollah Badakhshan +2 more
doaj +1 more source
Investigation of the Effect of Anakinra on Pentylenetetrazole-Induced Epileptic Seizures in Mice
Ahi Evran Medical Journal, 2021 Purpose: Disruption of the balance between gamma aminobutyric acid (GABA) and glutamate in the brain is one of the important factors contributing to seizure formation and epileptogenesis.
Ahmet Kemal FİLİZ +1 more
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Brain GABA and Glutamate Concentrations Following Chronic Gabapentin Administration: A Convenience Sample Studied During Early Abstinence From Alcohol. [PDF]
, 2018 Gabapentin (GBP), a GABA analog that may also affect glutamate (Glu) production, can normalize GABA and Glu tone during early abstinence from alcohol, effectively treating withdrawal symptoms and facilitating recovery.
Durazzo, Timothy C +3 more
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AksonaHighlight: • Reduced cerebellar Purkinje cell numbers and altered dendritic trees due to cell deaths were reported in hyperglycemia. • In hyperglycemia, altered GABAergic neurotransmissions are due to lower GABA synthesis and its receptors expression
Viskasari P Kalanjati +2 more
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Psychotic Episodes After Vigabatrine Treatment: A Case Report
Psychiatry and Behavioral Sciences, 2020 Vigabatrin is an antiepileptic that functions by increasing ɣ-aminobutyric acid (GABA) levels in the brain. Like other antiepileptics, it also causes neuropsychiatric side effects. Among these side effects, psychosis draws particular attention. Drug-
Erdem Uysal +2 more
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Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication. [PDF]
, 2017 A key goal of diabetes research is to develop treatments to safely promote human ß-cell replication. It has recently become appreciated that activation of γ-aminobutyric acid receptors (GABA-Rs) on ß-cells can promote their survival and replication.
Dang, Hoa +3 more
core +1 more source
Open Veterinary JournalBackground: The gamma-aminobutyric acid GABA receptors are considered the main inhibitory neurotransmitter receptors in mammalian brain and they have been proved to be existing in non-neuronal cells. Aim: Lorazepam which is one of the benzodiazepines,
Mohammed Abdullah Ajeel +1 more
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