Results 121 to 130 of about 2,290,618 (347)
Intracellular chloride concentration influences the GABAA receptor subunit composition
Nature Communications, 2012 GABAA receptors (GABAARs) exist as different subtype variants showing unique functional properties and defined spatio-temporal expression pattern. The molecular mechanisms underlying the developmental expression of different GABAAR are largely unknown ...
Francesca Succol +4 more
semanticscholar +1 more source
Nature's Brewery to Bedtime: The Role of Hops in GABAA Receptor Modulation and Sleep Promotion [PDF]
Doctoral Dissertation University of Turku. ISBN: 978-951-29-9577-6
(2023)Insomnia often requires pharmacological interventions, with benzodiazepines and Z-drugs enhancing GABA's inhibitory effects by stabilizing GABAA receptor chloride ion channels. Prolonged use, however, raises dependency and cognitive concerns. Humulus lupulus (hops) is gaining attention as a natural relaxant and sleep aid, potentially modulating GABAA ...
arxiv
Coral reef fish visual adaptations to a changing world
Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Coral reef ecosystems show fluctuations in their prevailing light environment in response to both regular (e.g. between seasons) and more prevalent stochastic events (e.g. human‐induced sediment runoff).
Abigail Shaughnessy, Fabio Cortesi
wiley +1 more source
Localization of the GABAA receptor in the rat brain with a monoclonal antibody to the 57,000 Mr peptide of the GABAA receptor/benzodiazepine receptor/Cl- channel complex [PDF]
, 1988 AL de Blas +2 more
openalex +1 more source
Journal of Biological Chemistry, 2012 Background: GABAA receptor γ2 and δ subunits are thought to be responsible for synaptic and extrasynaptic targeting. Results: We demonstrate here that α2 and α6 subunits can target δ/γ2 chimeras to synaptic and extrasynaptic sites.
Xia Wu +8 more
semanticscholar +1 more source
Accuracy of direct gradient sensing by cell-surface receptors [PDF]
arXiv, 2009 Chemotactic cells of eukaryotic organisms are able to accurately sense shallow chemical concentration gradients using cell-surface receptors. This sensing ability is remarkable as cells must be able to spatially resolve small fractional differences in the numbers of particles randomly arriving at cell-surface receptors by diffusion.
arxiv
Molecular Ecology Resources, EarlyView.ABSTRACT Bats have evolved highly adapted auditory mechanisms associated with ecological specialisation. However, there is scattered knowledge about the neurophysiological and cellular basis underlying high‐frequency hearing in echolocating bats. Herein, the total cochlear cell atlas of Rhinolophus ferrumequinum (constant frequency (CF) bat) and Myotis
Xue Wang +14 more
wiley +1 more source
Journal of Pharmacological Sciences, 2007 We investigated the involvement of γ-aminobutyric acidA (GABAA) receptors in the neuroprotective effect of γ-glutamylethylamide (theanine), a component of Japanese green tea, following a 4-h middle cerebral artery (MCA) occlusion in mice.
Nobuaki Egashira +6 more
doaj
Insulin Regulates GABAA Receptor-Mediated Tonic Currents in the Prefrontal Cortex
Frontiers in Neuroscience, 2018 Recent studies, have shown that insulin increases extrasynaptic GABAA receptor-mediated currents in the hippocampus, causing alterations of neuronal excitability.
Saraí Trujeque-Ramos +6 more
doaj +1 more source
Immunohistochemical localization of benzodiazepine/GABAA receptors in the human hippocampal formation [PDF]
, 1988 CR Houser +3 more
openalex +1 more source