Results 121 to 130 of about 41,401 (221)

Editorial: The GABAA receptor: a target of pharmacologically active molecules. [PDF]

Front Pharmacol
Ernst M, Lu W, Mattei C.
europepmc   +1 more source

Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder

Journal of Internal Medicine, Volume 299, Issue 3, Page 302-327, March 2026.
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley   +1 more source

Early developmental changes in GABAA receptor expression in nucleus accumbens medium spiny neurons. [PDF]

Front Neurosci
Wang ZZ, Folorunso OO, Morris K, Berretta S, Engin E.   +4 more
europepmc   +1 more source

Use of transcutaneous spinal cord stimulation to explore inhibitory and facilitatory circuits in muscles of the human lower limb

Experimental Physiology, Volume 111, Issue 3, Page 1191-1209, 1 March 2026.
Abstract The aim of this study was to explore the primary afferent depolarization mechanism, to determine whether the soleus transspinal evoked potential (TEP), elicited through transcutaneous spinal cord stimulation over the L1–L2 level, is modulated by presynaptic inhibition and heteronymous facilitation, similar to the Hoffmann (H) reflex, elicited ...
Julia Sordet, Maria Papaiordanidou, Nicolas Amiez, Ioannis Amiridis, Jean‐Pierre Quenot, Alain Martin   +5 more
wiley   +1 more source

Biomarker-Based Pharmacological Characterization of ENX-102, a Novel α2/3/5 Subtype-Selective GABAA Receptor Positive Allo-Steric Modulator: Translational Insights from Rodent and Human Studies. [PDF]

Cells
Nettesheim P, Vadodaria KC, Vanover KE, Borghans LGJM, Arce E, Brubaker W, Cunningham S, Parks S, Serrats J, Sudarsan V, Taylor E, Klaassen E, Stuurman FE, Jacobs GE.   +13 more
europepmc   +1 more source

Φ value analysis underscores strong functional and structural compactness of the GABA_A receptor. [PDF]

Proc Natl Acad Sci U S A
Michałowski MA, Terejko K, Gos M, Iżykowska I, Czyżewska MM, Kłopotowski K, Kaczor PT, Brzóstowicz A, Płużek E, Migdałek M, Mozrzymas JW.   +10 more
europepmc   +1 more source

Curcumin reduces pain after spinal cord injury in rats by decreasing oxidative stress and increasing GABAA receptor and GAD65 levels. [PDF]

Sci Rep
Hadadi M, Farazi MM, Mehrabani M, Tashakori-Miyanroudi M, Behroozi Z.   +4 more
europepmc   +1 more source

Tonic GABA_A receptor currents in Cerebellar Purkinje cells of wild-type and DMD^mdx mice. [PDF]

Sci Rep
Mitra S, Khatri SN, Pugh JR.
europepmc   +1 more source

The GABA_A receptor RDL modulates the auditory sensitivity of malaria mosquitoes. [PDF]

iScience
Ellis DA, Alampounti AC, Suppermpool A, Georgiades M, Freeman E, Bagi J, Tytheridge S, Terrazas-Duque D, Albert JT, Andrés M.   +9 more
europepmc   +1 more source

Perioperative switching to lemborexant for prevention of delirium in older cancer patients with insomnia taking GABA_A receptor agonists: a retrospective study. [PDF]

Support Care Cancer
Terada T, Hirayama T, Sadahiro R, Wada S, Yamaguchi J, Nishikawa E, Nakahara R, Washizuka S, Matsuoka H.   +8 more
europepmc   +1 more source