Results 31 to 40 of about 6,345 (201)

Gabapentinoids: The rise of a new misuse epidemics?

open access: yes, 2021
Gabapentinoids and opioids have in common that they are used in medicine in the treatment of pain, and by addicts in recreational use. In recent years, in the context of the "opioid epidemics", gabapentinoids, which had a reputation for low risk of abuse,
Hofmann, Michel, Besson, Marie
core   +1 more source

Effects of Gabapentinoids on Heroin-Induced Ventilatory Depression and Reversal by Naloxone

open access: yes, 2023
Despite an increasing prevalence of gabapentinoids (gabapentin and pregabalin) in opioid overdose deaths, little research has evaluated potentially harmful interactions between gabapentinoids and opioids.
Shawn M. Flynn (14724621)   +1 more
core   +1 more source

Impact of Withdrawal of Extended-Release Morphine 5 mg on Hospital Analgesic Utilization. [PDF]

open access: yesBasic Clin Pharmacol Toxicol
Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
Eisenhardt MVG   +4 more
europepmc   +2 more sources

A Systematic Review of the Clinical Use of Gabapentin and Pregabalin in Bipolar Disorder

open access: yesPharmaceuticals, 2021
Despite its prevalence and disease burden, several chasms still exist with regard to the pharmacotherapy of bipolar disorder (BD). Polypharmacy is commonly encountered as a significant proportion of patients remain symptomatic, and the management of the ...
Qin Xiang Ng   +5 more
doaj   +1 more source

Comparison of Oral Labetolol and Oral Pregabalin in Attenuating Pressor Response to Endotracheal Intubation in Patients undergoing Mastoidectomy under General Anaesthesia- A Randomised Control Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2022
Introduction: Direct laryngoscopy and tracheal intubation provoke stress response side-effects in the form of hypertension, tachycardia, and dysrhythmia which are long-standing concerns for anaesthetists. Various drugs and techniques have been tried over
Ambar Khan   +7 more
doaj   +1 more source

Incidence and Costs of Gabapentinoids-Associated Adverse Events

open access: yes, 2023
Scoping Review Protocol Goal of the review Three gabapentinoids (gabapentin, pregabalin, and mirogabalin) are currently approved for medical use for conditions such as seizures, neuropathic pain, and anxiety disorders.
Tania Morin (14834869)   +4 more
core   +1 more source

Post-Amputation Pain: Combined Analyses of Randomized Controlled Trials Evaluating Opioids and Gabapentinoids versus Placebo

open access: yesJournal of Pain Research
Adam Arthur,1,2 Leonardo Kapural,3 Richard P Chiacchierini,4 Nicholas J Hargus,5 William R Patterson5 1Department of Neurological Surgery, Semmes-Murphey Neurologic and Spine Institute, Memphis, TN, USA; 2Department of Neurosurgery, University of ...
Leonardo Kapural
exaly   +2 more sources

Heme oxygenase-1 inducer and carbon monoxide–releasing molecule enhance the effects of gabapentinoids by modulating glial activation during neuropathic pain in mice

open access: yesPAIN Reports, 2018
. Introduction:. Neuropathic pain is one of the most difficult-to-treat symptoms. Although gabapentinoids are classified as first-line drugs, they have only modest efficacy. Objectives:. The aim of this study was to investigate whether treatment with the
Kohei Godai, Yuichi Kanmura
doaj   +1 more source

A critical appraisal of gabapentinoids for pain in cancer patients. [PDF]

open access: yes, 2018
Gabapentinoids are frequently used in the management of cancer pain. In recent Cochrane systematic reviews, although there was an abundance of evidence relating to non-cancer pain, only a few studies related to cancer pain.
Bennett, MI, Jordan, RI, Mulvey, MR
core   +1 more source

The Anti-Allodynic Gabapentinoids: Myths, Paradoxes, and Acute Effects [PDF]

open access: yes, 2017
The gabapentinoids (pregabalin and gabapentin) are first line treatments for neuropathic pain. They exert their actions by binding to the α2δ accessory subunits of voltage-gated Ca2+ channels.
Smith, PA, Alles, SRA
core   +1 more source

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