Results 31 to 40 of about 6,786 (213)

Effects of Gabapentinoids on Heroin-Induced Ventilatory Depression and Reversal by Naloxone

open access: yes, 2023
Despite an increasing prevalence of gabapentinoids (gabapentin and pregabalin) in opioid overdose deaths, little research has evaluated potentially harmful interactions between gabapentinoids and opioids.
Shawn M. Flynn (14724621)   +1 more
core   +1 more source

Gabapentinoïdes : mésusages et addictions [Gabapentinoids : misuses and addictions]

open access: yes, 2021
Cases of addictions and misuses on gabapentinoids are increasingly reported. But the underlying pharmacological mechanism is not completely understood.
Vandenberghe, F.   +15 more
core   +1 more source

Heme oxygenase-1 inducer and carbon monoxide–releasing molecule enhance the effects of gabapentinoids by modulating glial activation during neuropathic pain in mice

open access: yesPAIN Reports, 2018
. Introduction:. Neuropathic pain is one of the most difficult-to-treat symptoms. Although gabapentinoids are classified as first-line drugs, they have only modest efficacy. Objectives:. The aim of this study was to investigate whether treatment with the
Kohei Godai, Yuichi Kanmura
doaj   +1 more source

Gabapentinoids for Chronic Pain: A Comprehensive Review of Current Literature on Efficacy, Safety and Withdrawal

open access: yes, 2021
Gabapentinoids, pregabalin (LyricaTM) and gabapentin (NeurontinTM) are anticonvulsants that have been approved for chronic pain conditions such as diabetic peripheral neuropathy, postherpetic neuralgia, fibromyalgia, and are also widely prescribed off ...
Amy Kathryn Granger
core   +1 more source

Selected baseline characteristics of older adults with CNCP by treatment with concurrent use of gabapentinoids and opioids or opioids only.

open access: yes, 2022
Selected baseline characteristics of older adults with CNCP by treatment with concurrent use of gabapentinoids and opioids or opioids only.
Yu-Jung Jenny Wei (7821602)   +4 more
core   +1 more source

Effect of OCTN1 rs1050152 and rs3792876 polymorphisms on pain score difference in responders (complete and partial) after gabapentinoids treatment.

open access: yes, 2022
Effect of OCTN1 rs1050152 and rs3792876 polymorphisms on pain score difference in responders (complete and partial) after gabapentinoids treatment.
Moosa Khan (12542696)   +6 more
core   +1 more source

Efficacy of Low-dose Naltrexone Compared to Gabapentinoids in Fibromyalgia [PDF]

open access: yes
• . This literature review evaluates the efficacy, safety, and tolerability of low-dose naltrexone (LDN) compared to gabapentinoids, including gabapentin and pregabalin, in the management of fibromyalgia symptoms.
Boen, Dillon
core   +4 more sources

Off-Label Day-of-Surgery Gabapentinoids and Prolonged Opioid Use: A Retrospective Cohort Study of Medicare Patients using Electronic Health Records [PDF]

open access: yes, 2021
Background: Gabapentinoids are increasingly incorporated into multimodal analgesia protocols for surgery. However, these drugs are not approved by the US FDA for use in managing surgical pain , and little is known regarding the effects of this off-label ...
Jonsson-Funk, Michele   +10 more
core   +1 more source

Gabapentinoids: A review of the literature

open access: yes, 2021
The objective of this review is to produce a synthesis of the state of knowledge regarding the epidemiology, pharmacology, clinical and analytical toxicology of gabapentinoids. The pharmacological class of gabapentinoids is mainly represented by gabapentin and pregabalin, which were marketed around the 2000s. Soon after their marketing, cases of misuse
Bargel, Sophie   +7 more
openaire   +1 more source

Gabapentinoid Benefit and Risk Stratification: Mechanisms Over Myth

open access: yesPain and Therapy, 2020
Introduction Recent years have seen a dramatic escalation of off-label prescribing for gabapentin and pregabalin (gabapentinoids) owing in part to generic versions of each being released over the past two decades, but also in part as a response to ...
Heath McAnally, Udo Bonnet, Alan D. Kaye
doaj   +1 more source

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