Results 121 to 130 of about 2,771 (143)

Conserved LIR-specific interaction of Sigma-1 receptor and GABARAP. [PDF]

iScience
Baeken MW, Christ M, Schmitt D, Trein W, Nagel H, Clement AM, Körschgen H, Behl C.   +7 more
europepmc   +1 more source

Decoding the molecular mechanism of selective autophagy of glycogen mediated by autophagy receptor STBD1. [PDF]

Proc Natl Acad Sci U S A
Zhang Y, Sun Y, Shi J, Xu P, Wang Y, Liu J, Gong X, Wang Y, Tang Y, Liu H, Zhou X, Lin Z, Baba O, Morita T, Yu B, Pan L.   +15 more
europepmc   +1 more source

Accurate de novo design of high-affinity protein-binding macrocycles using deep learning. [PDF]

Nat Chem Biol
Rettie SA, Juergens D, Adebomi V, Bueso YF, Zhao Q, Leveille AN, Liu A, Bera AK, Wilms JA, Üffing A, Kang A, Brackenbrough E, Lamb M, Gerben SR, Murray A, Levine PM, Schneider M, Vasireddy V, Ovchinnikov S, Weiergräber OH, Willbold D, Kritzer JA, Mougous JD, Baker D, DiMaio F, Bhardwaj G.   +25 more
europepmc   +1 more source

Identification of HSP90 as a new GABARAPL1 (GEC1)-interacting protein [PDF]

Biochimie, 2012
GABARAPL1 belongs to the small family of GABARAP proteins (including GABARAP, GABARAPL1 and GABARAPL2/GATE-16), one of the two subfamilies of the yeast Atg8 orthologue. GABARAPL1 is involved in the intracellular transport of receptors, via an interaction with tubulin and GABA(A) or kappa opioid receptors, and also participates in autophagy and cell ...
Sophie Croizier, Wilfrid Boireau, Michael Boyer-Guittaut   +2 more
exaly   +3 more sources

Gabarapl1 mediates androgen-regulated autophagy in prostate cancer

Tumor Biology, 2015
Autophagy plays an important role in prostate cancer development. It promotes tumor cell survival and was found to be associated with androgen pathway. In the present study, we found that GABA(A) receptor-associated protein like 1 (Gabarapl1), a ubiquitin-like modifier, participates in the regulation of autophagy.
You Zhou, Bing Su
exaly   +4 more sources

GABARAPL1 (GEC1): Original or copycat? [PDF]

Autophagy, 2011
The GABARAPL1 (GABARAP-LIKE 1) gene was first described as an early estrogen-regulated gene that shares a high sequence homology with GABARAP and is thus a part of the GABARAP family. GABARAPL1, like GABARAP, interacts with the GABAA receptor and tubulin and promotes tubulin polymerization.
Annick Fraichard, Regis Delage-Mourroux, M Jouvenot   +2 more
exaly   +3 more sources

GABARAPL1 (GEC1) associates with autophagic vesicles [PDF]

Autophagy, 2010
Gabarapl1 (gec1) was first described as an estrogen regulated gene which shares a high sequence homology with the gabarap gene. We previously demonstrated that GABARAPL1, like GABARAP, interacts with the GABAA receptor and tubulin and promotes tubulin polymerization.
Annick Fraichard, Regis Delage-Mourroux, M Jouvenot   +2 more
exaly   +3 more sources

The autophagy GABARAPL1 gene is epigenetically regulated in breast cancer models [PDF]

BMC Cancer, 2015
The GABARAP family members (GABARAP, GABARAPL1/GEC1 and GABARAPL2 /GATE-16) are involved in the intracellular transport of receptors and the autophagy pathway. We previously reported that GABARAPL1 expression was frequently downregulated in cancer cells while a high GABARAPL1 expression is a good prognosis marker for patients with lymph node-positive ...
Eric Hervouet, Annick Fraichard, Pascale Adami   +2 more
exaly   +3 more sources