Results 21 to 30 of about 17,987 (169)

Alkaloid Profiling and Anti-Cholinesterase Potential of Three Different Genera of Amaryllidaceae Collected in Ecuador: Urceolina Rchb., Clinanthus Herb. and Stenomesson Herb. [PDF]

Life
Ecuador is an important center of biodiversity for the plant subfamily Amaryllidoideae, known for its important bioactive molecules. This study aimed to assess the chemical and biological potential of four different Amaryllidoideae species collected in ...
Luciana R. Tallini, Karen Acosta León, Raúl Chamorro, Edison H. Osorio, Jaume Bastida, Lou Jost, Nora H. Oleas   +6 more
doaj   +2 more sources

Integrated Phytochemical Profiling and Multifunctional Bioactivities of Bellis annua Extracts Obtained by Distinct Extraction Techniques. [PDF]

ChemistryOpen
The present study evaluates the effect of maceration, Soxhlet, and ultrasound‐assisted extraction on the phytochemical composition and biological activities of Bellis annua. LC–ESI–MS/MS analysis revealed chlorogenic acid as the dominant compound, while UAE enhanced flavonoid content and overall antioxidant capacity.
Kargin Solmaz FO, Sarikurkcu C, Tepe B.
europepmc   +2 more sources

Organ-Specific Phytochemical Composition and Bioactivity Profiling of Chaerophyllum aksekiense: A Multiassay Antioxidant, Enzyme Inhibition, and Correlation-Based Evaluation. [PDF]

ChemistryOpen
This study reveals the organ‐specific phytochemical specialization of the endemic Chaerophyllum aksekiense for the first time. Although leaves exhibit the highest phenolic content and antioxidant capacity, flowers stand out with flavonoid accumulation, and roots demonstrate potent enzyme inhibition.
Selvi B, Bozdemir EA.
europepmc   +2 more sources

Integrating Narcissus-derived galanthamine production into traditional upland farming systems

Scientific Reports, 2021
Alzheimer’s disease (AD) is a disorder associated with progressive degeneration of memory and cognitive function. Galantamine is a licenced treatment for AD but supplies of the plant alkaloid that it is produced from, galanthamine, are limited.
M. D. Fraser, H. E. Vallin, J. R. T. Davies, G. E. Rowlands, X. Chang   +4 more
doaj   +1 more source

Analysis on the thermal decomposition kinetics and storage period of biomass-based lycorine galanthamine

Frontiers in Chemistry, 2023
As global ageing deepens and galanthamine is the preferred clinical drug for the treatment of mild to moderate Alzheimer’s disease, it will be valuable to examine the behaviour and mechanism of galanthamine’s thermal decomposition for its quality control,
Chong Qin, Chong Qin, Weihong Ling, Chunlian Tian   +3 more
doaj   +1 more source

Stereocontrolled Synthesis of (−)-Galanthamine [PDF]

Organic Letters, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Satcharoen, V., McLean, N.J., Kemp, S.C., Camp, N.P., Brown, R.C.D.   +4 more
openaire   +3 more sources

Chemical Survey of Three Species of the Genus Rauhia Traub (Amaryllidaceae)

Plants, 2022
Plant biodiversity is an important source of compounds with medicinal properties. The alkaloid galanthamine, first isolated from Galanthus woronowii (Amaryllidaceae), is approved by the FDA for the palliative treatment of mild to moderate Alzheimer’s ...
Luciana R. Tallini, Edison H. Osorio, Strahil Berkov, Laura Torras-Claveria, María L. Rodríguez-Escobar, Francesc Viladomat, Alan W. Meerow, Jaume Bastida   +7 more
doaj   +1 more source

Cloning and characterization of a norbelladine 4'-O-methyltransferase involved in the biosynthesis of the Alzheimer's drug galanthamine in Narcissus sp. aff. pseudonarcissus. [PDF]

PLoS ONE, 2014
Galanthamine is an Amaryllidaceae alkaloid used to treat the symptoms of Alzheimer's disease. This compound is primarily isolated from daffodil (Narcissus spp.), snowdrop (Galanthus spp.), and summer snowflake (Leucojum aestivum).
Matthew B Kilgore, Megan M Augustin, Courtney M Starks, Mark O'Neil-Johnson, Gregory D May, John A Crow, Toni M Kutchan   +6 more
doaj   +1 more source

Phenolic Acids and Amaryllidaceae Alkaloids Profiles in Leucojum aestivum L. In Vitro Plants Grown under Different Light Conditions

Molecules, 2023
Light-emitting diodes (LEDs) have emerged as efficient light sources for promoting in vitro plant growth and primary and secondary metabolite biosynthesis. This study investigated the effects of blue, red, and white-red LED lights on plant biomass growth,
Emilia Morańska, Magdalena Simlat, Marzena Warchoł, Edyta Skrzypek, Piotr Waligórski, Dominique Laurain-Mattar, Rosella Spina, Agata Ptak   +7 more
doaj   +1 more source

Endophytic bacteria from in vitro culture of Leucojum aestivum L. a new source of galanthamine and elicitor of alkaloid biosynthesis

Scientific Reports, 2022
Leucojum aestivum is known for its ability to biosynthesize alkaloids with therapeutic properties, among which galanthamine used for the treatment of Alzheimer's disease. New sources of this alkaloid are still being explored.
Agata Ptak, Emilia Morańska, Marzena Warchoł, Artur Gurgul, Edyta Skrzypek, Michał Dziurka, Dominique Laurain-Mattar, Rosella Spina, Anita Jaglarz, Magdalena Simlat   +9 more
doaj   +1 more source