Results 21 to 30 of about 21,078 (260)

Endophytic bacteria from in vitro culture of Leucojum aestivum L. a new source of galanthamine and elicitor of alkaloid biosynthesis

open access: yesScientific Reports, 2022
Leucojum aestivum is known for its ability to biosynthesize alkaloids with therapeutic properties, among which galanthamine used for the treatment of Alzheimer's disease. New sources of this alkaloid are still being explored.
Agata Ptak   +9 more
doaj   +1 more source

Semisynthetic Derivatives of Selected Amaryllidaceae Alkaloids as a New Class of Antimycobacterial Agents

open access: yesMolecules, 2021
The search for novel antimycobacterial drugs is a matter of urgency, since tuberculosis is still one of the top ten causes of death from a single infectious agent, killing more than 1.4 million people worldwide each year.
Negar Maafi   +14 more
doaj   +1 more source

Acetylcholinesterase Inhibition Activity of Hippeastrum papilio (Ravenna) Van Scheepen (Amaryllidaceae) Using Zebrafish Brain Homogenates

open access: yesLife, 2023
The Amaryllidaceae family constitutes an interesting source of exclusive alkaloids with a broad spectrum of biological activity. Galanthamine, the most relevant one, has been commercialized for the palliative treatment of Alzheimer’s disease symptoms ...
Luciana R. Tallini   +9 more
doaj   +1 more source

Unlocking the Antioxidant, Enzyme Inhibitory and Acaricidal Potential of <i>Azadirachta indica</i> Phytoconstituents Using In Vitro and In Silico Approaches. [PDF]

open access: yesFood Sci Nutr
The study evaluated the acaricidal potential of bioactive components of Azadirachta indica against scabies mortality using both in vitro and in silico methodologies. Sarcoptes scabiei were stimulated with Azadirachta indica at four concentrations (25–100 mg/mL) at different intervals.
Fatima T   +8 more
europepmc   +2 more sources

Thiol-reactive analogues of galanthamine, codeine and morphine as potential probes to interrogate allosteric binding within nAChRs [PDF]

open access: yes, 2016
Alkaloids including galanthamine (1) and codeine (2) are reported to be positive allosteric modulators of nicotinic acetylcholine receptors (nAChRs) but the binding sites responsible for this activity are not known with certainty.
Balle, Thomas   +3 more
core   +1 more source

Acetylcholinesterase-inhibiting Alkaloids from Zephyranthes concolor

open access: yesMolecules, 2011
The bulbs and aerial parts of Zephyranthes concolor (Lindl.) Benth. & Hook. f. (Amaryllidaceae), an endemic species to Mexico, were found to contain the alkaloids chlidanthine, galanthamine, galanthamine N-oxide, lycorine, galwesine, and ...
Sebastien Arseneau   +9 more
doaj   +1 more source

Biological Activities of Snowdrop (Galanthus spp., Family Amaryllidaceae)

open access: yesFrontiers in Pharmacology, 2021
Snowdrop is an iconic early spring flowering plant of the genus Galanthus (Amaryllidaceae). Galanthus species (Galanthus spp.) are economically important plants as ornaments. Galanthus spp has gained significance scientific and commercial interest due to
Chee Kei Kong   +13 more
doaj   +1 more source

Comparative study of the vibrational optical activity techniques in structure elucidation : the case of galantamine [PDF]

open access: yes, 2019
The absolute configuration of the alkaloid galantamine was studied using a range of solution-state techniques; nuclear magnetic resonance (NMR), vibrational circular dichroism (VCD), and Raman optical activity (ROA). While the combined use of NMR and VCD
Bultinck, Patrick   +4 more
core   +2 more sources

Narcissus dubius, Narcisse Douteux [PDF]

open access: yes, 2018
This species is endemic to southern France and eastern Spain. It is assessed as Least Concern because it has a widespread distribution, occurs in several protected areas throughout its range and its population is not expected to significantly decline in ...
Carapeto, André   +5 more
core   +1 more source

Recent Progress in Amaryllidaceae Biotechnology

open access: yesMolecules, 2020
Plants belonging to the monocotyledonous Amaryllidaceae family include about 1100 species divided among 75 genera. They are well known as medicinal and ornamental plants, producing pharmaceutically important alkaloids, the most intensively investigated ...
Vasil Georgiev   +2 more
doaj   +1 more source

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