Results 61 to 70 of about 18,076 (169)

Exploring the Multifunctional Agents of Flavonoid‐Rich Beet Leaf Extracts: Insights From Experimental and Computational Studies

Food Safety and Health, Volume 3, Issue 4, Page 723-739, October 2025.
ABSTRACT This study evaluated the multifunctional ability of Beta vulgaris leaves in dual therapy for Alzheimer's disease (AD) and type 2 diabetes (T2D). Flavonoid‐rich extracts of B. vulgaris leaves (FREBVL) were tested for their antidiabetic properties. The inhibition of α‐amylase and α‐glucosidase was assessed. Anti‐cholinesterase activities against
Gideon Ampoma Gyebi, Damilare Emmanuel Rotimi, Moyosoreoluwa Oduba, Ifeoma Nnonyelu, Matthew Iyobhebhe, Musiliyu Ayofe Salawu, Adebola Busola Ojo, Odunayo Anthonia Taiwo, Adesoji Alani Olanrewaju, Abel Kolawole Oyebamiji, Mubarak Alruwaili, Naif H. Ali, Saud A. Alnaaim, Bshra A. Alsfouk, Gaber El‐Saber Batiha, Oluwafemi Adeleke Ojo   +15 more
wiley   +1 more source

Biosynthesis, total synthesis, and pharmacological activities of galanthamine and its analogues

Medicinal Plant Biology
Galanthamine (GAL), an isoquinoline alkaloid characterized by a unique tetracyclic skeleton bearing three chiral centers, is a potent and selective acetylcholinesterase inhibitor with established therapeutic significance.
Lan Kang, Yapeng Wang, Kang Chen, Zhiwei Duan, Yang Li, Siyu Shen, Zihan Jia, Yuru Tong, Luqi Huang   +8 more
doaj   +1 more source

Deciphering of nutritional profile, therapeutic potential, and networking of bioactive compounds of Moringa oleifera: A comprehensive review

Food Biomacromolecules, Volume 2, Issue 3, Page 271-287, September 2025.
The graphical abstract signifies the nutritional profile of various parts of the Moringa oleifera plant, including dried leaves, fresh leaves, leaf powder, seeds, and pods; along with it’s bioactive substance and protein profiling of aqueous concentrates derived from the fruit, seed, and leaf.
Rajesh Kumar, Sunita Khatak, Vandana, Adarsh Kumar Shukla, Surbhi Panwar, Ashwani Kumar   +5 more
wiley   +1 more source

Cholinesterase Inhibition Activity, Alkaloid Profiling and Molecular Docking of Chilean Rhodophiala (Amaryllidaceae)

Molecules, 2018
Amaryllidaceae plants are the commercial source of galanthamine, an alkaloid approved for the clinical treatment of Alzheimer’s disease. The chemistry and bioactivity of Chilean representatives of Rhodophiala genus from the family of Amaryllidaceae
Luciana R. Tallini, Jaume Bastida, Natalie Cortes, Edison H. Osorio, Cristina Theoduloz, Guillermo Schmeda-Hirschmann   +5 more
doaj   +1 more source

Acetylcholinesterase Inhibition within the Lycorine Series of Amaryllidaceae Alkaloids

Natural Product Communications, 2012
The plant family Amaryllidaceae occupies a privileged status within the botanical hierarchy due to its horticultural and ornamental appeal, as well as its widespread usage in the traditional medicinal practices of indigenous peoples across the globe.
Jerald J. Nair, Johannes van Staden
doaj   +1 more source

Amaryllidaceae Alkaloids from Zephyrantes Carinata and Their Evaluation as Cholinesterases (AChE and BChE) Inhibitors

Proceedings, 2019
The subfamily Amaryllidoideae within of the Amaryllidaceae family has an exclusive group of compounds called Amaryllidaceae alkaloids. Galanthamine, the most known Amaryllidaceae alkaloid, is approved by the FDA as an inhibitor of the enzyme ...
Karina Sierra, Natalie Cortés, Luciana R. Tallini, Warley de S. Borges, Jean Paulo de Andrade, Jaume Bastida, Edison Osorio Durango   +6 more
doaj   +1 more source

Leishmanicidal and Cholinesterase Inhibiting Activities of Phenolic Compounds from Allanblackia monticola and Symphonia globulifera

Molecules, 2007
In a preliminary antiprotozoal screening of several Clusiaceae species, the methanolic extracts of Allanblackia monticola and Symphonia globulifera showed high in vitro leishmanicidal activity.
Norbert Sewald, Etienne Tsamo, Muhammad Iqbal Choudhary, Qamar Naz, Marcel Kaiser, Joseph Ngoupayo, Krishna Prasad Devkota, Bernard Weniger, Catherine Vonthron-Sénécheau, Bruno Ndjakou Lenta   +9 more
doaj   +1 more source

Dissecting specialized metabolism in space: A MALDI-MSI atlas of Amaryllidaceae alkaloids in Hippeastrum papilio (Ravenna) Van Scheepen

Current Plant Biology
Amaryllidoideae produce specific specialized metabolites called Amaryllidaceae alkaloids (AAs), known for their pharmacological potential. The spatial distribution and biosynthesis within plant tissues, however, remain poorly understood.
Nuwan Sameera Liyanage, Natacha Mérindol, Sajjad Sobhanverdi, Kenneth Munk Pedersen, Christian Janfelt, Isabel Desgagné-Penix   +5 more
doaj   +1 more source

Cytotoxicity Studies of Lycorine Alkaloids of the Amaryllidaceae

Natural Product Communications, 2014
The plant family Amaryllidaceae is renowned for its unique alkaloid constituents which possess a significant array of structural diversity. Several of these alkaloids are known for their interesting biological properties, of which galanthamine and ...
Jerald J. Nair, Johannes van Staden
doaj   +1 more source

Acetylcholinesterase inhibition by somes promising Brazilian medicinal plants

Brazilian Journal of Biology
A microplate assay and a thin-layer chromatography (TLC) "in situ" assay based on the Ellman assay was used to screen for acetylcholinesterase inhibitors from ethyl acetate and methanol extracts of Brazilian medicinal plants of families that, according ...
CM. Feitosa, RM. Freitas, NNN. Luz, MZB. Bezerra, MTS. Trevisan   +4 more
doaj   +1 more source