Results 91 to 100 of about 8,950,905 (317)
Biomolecules, 2021 It has been almost 25 years since the discovery of galectin-7. This member of the galectin family has attracted interest from many working in the cancer field given its highly restricted expression profile in epithelial cells and the fact that cancers of
Yves St-Pierre
doaj +1 more source
The role of galectin-3 and galectin-9 in the chronic inflammation of rheumatoid arthritis [PDF]
, 2009 Fibroblasts are important regulators of inflammatory processes. The phenotype of fibroblasts differ according to anatomical site which may dtermine immune functions such as leukocyte accumulation and predilection for inflammatory disease in certain ...
Bik, Magadelena Anna
core
Advanced Science, EarlyView.A self‐supervised multi‐view graph fusion framework integrates spatial multi‐omics, excelling in domain identification and denoising. It reconstructs spatial pseudo‐expression, jointly analyzes multi‐omics data, infers RNA velocity, predicts spatial omics features from single‐cell multi‐omics, and detects spatially dark genes and transcription factors,
Yuejing Lu +8 more
wiley +1 more source
A role for Galectin‐9 in neutrophil trafficking
The FASEB Journal, 2012 Galectin‐9 (Gal‐9) was initially characterized as a potent eosinophil chemoattractant but has subsequently been found to have immunosuppressive effects in models of collagen‐ induced arthritis and carageenan paw oedema. Its effects on neutrophil recruitment and behavior during inflammation have not been thoroughly investigated.
Dianne Cooper +4 more
openaire +1 more source
Astrocyte galectin-9 potentiates microglial TNF secretion [PDF]
Journal of Neuroinflammation, 2014 Aberrant neuroinflammation is suspected to contribute to the pathogenesis of myriad neurological diseases. As such, determining the pathways that promote or inhibit glial activation is of interest. Activation of the surface glycoprotein T-cell immunoglobulin and mucin-domain containing protein 3 (Tim-3) by the lectin galectin-9 has been implicated in ...
Steelman, Andrew J, Li, Jianrong
openaire +2 more sources
Journal of Translational MedicineOverexpression of T-cell immunoglobulin and mucin domain-containing protein 3 (TIM3) is related to the exhaustion of CD8+ tumor-infiltrating lymphocytes (TILs) in diffuse large B-cell lymphoma (DLBCL).
Qiqi Zhu +5 more
semanticscholar +1 more source
mBio, 2021 The outbreak of SARS-CoV-2 infection has enormously impacted our lives. Clinical evidence has implicated the emergence of cytokine release syndrome as the prominent cause of mortality in COVID-19 patients.
N. Bozorgmehr +10 more
semanticscholar +1 more source
The role of Galectin-3 and Survivin in invasion and drug resistance in human cancer [PDF]
, 2003 Galectin-3 is an apoptosis-related gene previously found to be over-expressed in invasive tumours and to cause in v itroinvasiveness and metastasis in colon, breast and thyroid follicular cancer cells.
Linehan, Rasha
core
, 2019 IntroductionRheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation and hyperplasia, as well as cartilage and bone destruction. Several proteins are associated with the pathogenesis of the disease.
Ângela Luzia Branco Pinto Duarte +13 more
core +1 more source
Advanced Science, EarlyView.An intracellular magneto‐mechanical platform utilizing MSC‐targeted nanomotors is developed. After intra‐articular delivery, these nanomotors target endogenous BMSCs and are actuated within lysosomes to execute trans‐planar rotational‐bouncing motions under a rotating‐fluctuating 3D magnetic field, generating amplified mechanical stimulation.
Zhenguang Li +7 more
wiley +1 more source