Results 71 to 80 of about 8,950,905 (317)

Galectin-1 immunofluorescent staining.

open access: yes, 2023
Nuclei are labeled by Hoescht stain (blue, left panels). Gall bladder neuroendocrine neoplasm demonstrates positive galectin-1 (red, middle and right top panels) immunofluorescence compared to negative control (normal canine kidney).
Daniel Paulsen (5500241)   +9 more
core   +1 more source

Galectin-9: An anticancer molecule for gallbladder carcinoma

open access: yesInternational Journal of Oncology, 2016
Gallbladder cancer (GBC) is the most common and aggressive type of biliary tract cancer. There are various histological types of GBC, and the vast majority of GBC cases are adenocarcinomas. Squamous and adenosquamous carcinomas are rare GBC subtypes that are traditionally considered to be more aggressive and to be associated with a poorer prognosis ...
Tomoko, Tadokoro   +16 more
openaire   +3 more sources

Immunomodulator Galectin-9 is Increased in Blood and Skin of Patients with Bullous Pemphigoid

open access: yesActa Dermato-Venereologica, 2021
Massive recruitment of eosinophils into the dermis is a hallmark of bullous pemphigoid pathogenesis. Identifying the chemoattractant(s) guiding eosinophils into the skin in bullous pemphigoid is a prerequisite to thera­peutic targeting of eosinophil ...
Jasper Pruessmann   +8 more
doaj   +1 more source

Detection of inflammation- and neoplasia-associated alterations in human large intestine using plant/invertebrate lectins, galectin-1 and neoglycoproteins [PDF]

open access: yes, 1998
Commonly, plant and invertebrate lectins are accepted glycohistochemical tools for the analysis of normal and altered structures of glycans in histology and pathology.
Korabiowska, M.   +3 more
core   +1 more source

Lactose-Functionalized Carbosilane Glycodendrimers Are Highly Potent Multivalent Ligands for Galectin-9 Binding: Increased Glycan Affinity to Galectins Correlates with Aggregation Behavior

open access: yesBiomacromolecules, 2023
Galectins, the glycan binding proteins, and their respective carbohydrate ligands represent a unique fundamental regulatory network modulating a plethora of biological processes.
Monika Müllerová   +9 more
semanticscholar   +1 more source

A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection. [PDF]

open access: yesPLoS ONE, 2010
Approximately 200 million people throughout the world are infected with hepatitis C virus (HCV). One of the most striking features of HCV infection is its high propensity to establish persistence (approximately 70-80%) and progressive liver injury ...
John A Mengshol   +14 more
doaj   +1 more source

Galectin-9 restricts hepatitis B virus replication via p62/SQSTM1-mediated selective autophagy of viral core proteins

open access: yesNature Communications, 2022
Autophagy has been linked to a wide range of functions, including a degradative process that defends host cells against pathogens. Although the involvement of autophagy in HBV infection has become apparent, it remains unknown whether selective autophagy ...
K. Miyakawa   +11 more
semanticscholar   +1 more source

Data_Sheet_1_The Tim-3-Galectin-9 Pathway and Its Regulatory Mechanisms in Human Breast Cancer.docx

open access: yes, 2019
Human cancer cells operate a variety of effective molecular and signaling mechanisms which allow them to escape host immune surveillance and thus progress the disease.
Svetlana S. Sakhnevych (6559877)   +18 more
core   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

open access: yesAdvanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu   +12 more
wiley   +1 more source

Different angioregulatory activity of monovalent galectin-9 isoforms [PDF]

open access: yesAngiogenesis, 2018
Galectin-9 consists of two peptide-linked carbohydrate recognition domains (CRDs), but alternative splicing and proteolytic processing can give rise to multiple galectin-9 isoforms. Some of these consist of a single CRD and can exert different functions in cell biology.
Ed Aanhane   +6 more
openaire   +4 more sources

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