Results 191 to 200 of about 4,689,501 (274)

Transcriptomic and Proteomic Analyses Show Minimal Role for ST2 on MCPT5‐Expressing Mast Cells in Primary Heligmosomoides polygyrus bakeri Infection

Parasite Immunology, Volume 48, Issue 4, April 2026.
ABSTRACT The IL‐33/ST2 pathway is important as part of the type 2 immune response against helminth infections. Mast cells express the highest levels of the IL‐33 receptor subunit ST2 of any immune cell, and mast cells can mediate type 2 immune inflammation; however, the role of IL‐33‐driven mast cell responses in helminth infection is poorly understood.
Nicole W. P. Ong, Suzanne H. Hodge, Christa P. Baker, Danielle J. Smyth, Tania Frangova, Henry J. McSorley   +5 more
wiley   +1 more source

Overproduction of 42 Amino Acids Long Amyloid Beta Leads to Activation of Secretory Autophagy and Development of Drusen‐Like Structures Originating From Retinal Pigment Epithelium

The FASEB Journal, Volume 40, Issue 5, 15 March 2026.
The role of 42 amino acids long amyloid beta (Aβ) in the retinal pigment epithelium (RPE) was investigated using 5xFAD mice model overproducing Aβ. The RPE cells of 5xFAD mice showed increased oxidative stress, accumulation of autophagy‐destined proteins, increased expression of secretory autophagy markers, and increase in epithelial‐to‐mesenchymal ...
Johanna Ruuth, Toni Tamminen, Elisa Toropainen, Heikki Tanila, Juha M. T. Hyttinen, Tarja Malm, Kai Kaarniranta, Ali Koskela   +7 more
wiley   +1 more source

Ferroptosis inhibits biological behaviors of glioma cells by downregulating Galectin-9 transcriptional level via extracellular Acetyl-HMGB1. [PDF]

Sci Rep
Xu Y, Tan G, Zhu R.
europepmc   +1 more source

Galectin-9-An Emerging Glyco-Immune Checkpoint Target for Cancer Therapy. [PDF]

Int J Mol Sci
Karkempetzaki AI, Schatton T, Barthel SR.   +2 more
europepmc   +1 more source

Association of Galectin-9 Soluble Immune Checkpoint with Clinical Prognostic Markers in Patients with Chronic Lymphocytic Leukemia. [PDF]

Int J Mol Sci
Ntsethe A, Dludla PV, Nkambule BB.
europepmc   +1 more source

Differential Expression of Galectin-1 and Galectin-9 in Immune-Mediated Inflammatory Diseases. [PDF]

Int J Mol Sci
Valero-Martínez C, Pardines-Ortiz M, Montes N, Dauden E, Fernández-Gutierrez B, García-Planella E, Gomollón García F, Gratacós J, Pérez-Venegas JJ, Julía A, Marsal S, Lamana A, García-Vicuña R, González-Alvaro I, Triguero-Martínez A.   +14 more
europepmc   +1 more source

1333 FG-3165 is a novel galectin-9 neutralizing antibody that inhibits galectin-9-mediated dimerization of TIM-3 and galectin-9-induced apoptosis of CD4⁺ and CD8⁺ T cells

Regular and Young Investigator Award Abstracts, 2023
John Hunter, Prachi Bagadia, Selene Li, Mitch Brenner, Veronica Rodriguez, Mark Sternlicht, Todd Seeley, Dave Olsen, Gail Walkinshaw   +8 more
openaire   +2 more sources

Galectin-9 regulates dendritic cell polarity and uropod contraction by modulating RhoA activity. [PDF]

J Cell Biol
Franken GA, Warner H, Cuenca-Escalona J, Stehle IF, van Reijmersdal VPA, Klomp SE, Schreurs K, Rodgers-Furones A, Gokhale RR, Vullings M, Classens R, Di Blasio S, Dolen Y, van Deventer S, Wolf K, Wortel IMN, Hetmanski JHR, van Spriel AB, Querol Cano L.   +18 more
europepmc   +1 more source

Neutrophil-Galectin-9 Axis Linking Innate and Adaptive Immunity in ATL, Sézary Syndrome, COVID-19, and Psoriasis: An AI-Assisted Integrative Review. [PDF]

Reports (MDPI)
Hattori T.
europepmc   +1 more source

Role of galectin-9 in the development of gestational diabetes mellitus. [PDF]

Sci Rep
Albuayjan HHH, Watanabe M, Sugawara R, Katsuyama E, Mise K, Oi Y, Kanno A, Yang B, Tahara T, Nojima I, Nakatsuka A, Eguchi J, Maki J, Eto E, Hayata K, Masuyama H, Wada J.   +16 more
europepmc   +1 more source