Results 211 to 220 of about 8,950,905 (317)

Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma

eFood, Volume 7, Issue 3, June 2026.
Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie, Wei Fang, Zean Song, Zhang Yu, Ying Zhu, Shaoping Liu   +5 more
wiley   +1 more source

Low‐Dose H2O2 Priming Improves Performance Under Simulated Marine Heatwave Conditions in a Coastal Bivalve

Global Challenges, Volume 10, Issue 6, June 2026.
Low‐dose hydrogen peroxide priming shapes Manila clam responses to simulated marine heatwaves, which showed faster burrowing behavior, limited transcriptional disruption, and reduced opportunistic microbiota. A long‐term field trial confirms no detectable adverse effects, supporting redox‐based chemical priming as a feasible resilience strategy in ...
Chiara Mascitelli, Giovanna Monticelli, Alessandro Nardi, Giulia Dalla Rovere, Graziano Rilievo, Ilaria Bernardini, Nicole Macrì, Deborah Cesaroni, Valentina Tavolazzi, Gabriele Andreatta, Tomaso Patarnello, Luca Bargelloni, Luca Peruzza, Maura Benedetti, Massimo Milan   +14 more
wiley   +1 more source

A Dynamic Change of Microglial States Occurs During the Transition From Photoreceptor Degeneration to Regeneration in Zebrafish pde6c Mutants

Glia, Volume 74, Issue 6, June 2026.
Zebrafish pde6c mutants undergo photoreceptor degeneration from 5 dpf, but rods regenerate from 4 wpf. scRNA‐seq of retinal microglia reveals dynamic change of states between 5 dpf and 4 wpf. Two states emerge specifically during regeneration. ABSTRACT Microglia, brain‐resident immune cells, maintain brain homeostasis.
Darshini Ravishankar, Yuki Takeuchi, Ichiro Masai   +2 more
wiley   +1 more source

1333 FG-3165 is a novel galectin-9 neutralizing antibody that inhibits galectin-9-mediated dimerization of TIM-3 and galectin-9-induced apoptosis of CD4⁺ and CD8⁺ T cells

Regular and Young Investigator Award Abstracts, 2023
John Hunter, Prachi Bagadia, Selene Li, Mitch Brenner, Veronica Rodriguez, Mark Sternlicht, Todd Seeley, Dave Olsen, Gail Walkinshaw   +8 more
openaire   +2 more sources

Association of Galectin-9 Soluble Immune Checkpoint with Clinical Prognostic Markers in Patients with Chronic Lymphocytic Leukemia. [PDF]

Int J Mol Sci
Ntsethe A, Dludla PV, Nkambule BB.
europepmc   +1 more source

Differential Expression of Galectin-1 and Galectin-9 in Immune-Mediated Inflammatory Diseases. [PDF]

Int J Mol Sci
Valero-Martínez C, Pardines-Ortiz M, Montes N, Dauden E, Fernández-Gutierrez B, García-Planella E, Gomollón García F, Gratacós J, Pérez-Venegas JJ, Julía A, Marsal S, Lamana A, García-Vicuña R, González-Alvaro I, Triguero-Martínez A.   +14 more
europepmc   +1 more source

Human galectin-1 triggers apoptosis via ceramide mediated mitochondrial pathway [PDF]

, 2005
Ion Gabriella
core  

Galectin-3 enhances monocyte-derived macrophage efferocytosis of apoptotic granulocytes in asthma

Background: Galectin-3 is a 32 kDa protein secreted by macrophages involved in processes such as cell activation, chemotaxis and phagocytosis. Galectin-3 has previously been shown to improve the ability of airway macrophages to ingest apoptotic cells ...
Melanie Erriah (6173654), Michael Fricker (21135857), Johan Bylund (257844), Kavita Pabreja (21280574), Louise E. Donnelly (17190430), Anna Karlsson (21145), Katherine Baines (21132530), Jodie Simpson (21132032)   +7 more
core  

Mapping the Global Clinical Landscape of Pharmacological Therapies for Heart Failure With Preserved Ejection Fraction: An Analysis Based on ClinicalTrials.gov (2003–2025)

iMetaMed, Volume 2, Issue 2, June 2026.
This study analyzed 236 heart failure with preserved ejection fraction (HFpEF) pharmacological trials registered on ClinicalTrials.gov from 2003 to 2025, revealing a post‐2016 surge (76.3%), U.S. dominance (58.5%), and prominence of SGLT2 inhibitors/novel therapies (each 13.1%).
Yucheng Hou, Jingwei Zhao, Yuqian Tang, Tan Liu, Zhiao Zhang, Ziheng Wang, Han Shen   +6 more
wiley   +1 more source

Galectin-9 regulates dendritic cell polarity and uropod contraction by modulating RhoA activity. [PDF]

J Cell Biol
Franken GA, Warner H, Cuenca-Escalona J, Stehle IF, van Reijmersdal VPA, Klomp SE, Schreurs K, Rodgers-Furones A, Gokhale RR, Vullings M, Classens R, Di Blasio S, Dolen Y, van Deventer S, Wolf K, Wortel IMN, Hetmanski JHR, van Spriel AB, Querol Cano L.   +18 more
europepmc   +1 more source