Results 231 to 240 of about 8,950,905 (317)

The Tumor Immune Microenvironment in Endometrial Cancer: Composition, Molecular Subtypes, and Therapeutic Implications

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Endometrial cancer (EC), a major gynecologic malignancy and a representative “cold tumor”, exhibits a tumor immune microenvironment (TIME) influenced by a broad range of cellular and molecular elements, immunosuppressive signals, and pathways of immune evasion.
Jingxuan Ye, Yashi Shi, Alexander Mustea, Xiaodan Mao, Pengming Sun   +4 more
wiley   +1 more source

Galectin-9 treatment is cytotoxic for B cell lymphoma by disrupting autophagy. [PDF]

Front Pharmacol
Koll L, Lourens HJ, Marsman G, de Haan S, Niki T, Huls GA, Bremer E, Wiersma VR.   +7 more
europepmc   +1 more source

Cancer‐Associated Fibroblasts: Central Players in the Plastic Pancreatic Cancer Microenvironment and Therapeutic Targeting

Organ Medicine, Volume 3, Issue 2, Page 76-86, June 2026.
Cancer‐associated fibroblasts (CAFs) are key regulators of the pancreatic tumor microenvironment. Through metabolic reprogramming, CAFs support tumor growth by providing nutrients and remodeling extracellular matrix. CAF heterogeneity, including myCAF, iCAF, and apCAF subsets, contributes to immune modulation and therapeutic resistance.
Ziyi Qin, Jinyang Ma, Rui Ju, Lei Guo
wiley   +1 more source

Correction: Tumor-derived exosomal tsRNA 3'tiRNA-AlaCGC in promoting fibroblast senescence and Galectin-9 secretion to induce immune tolerance in lung adenocarcinoma. [PDF]

Cell Death Discov
Zhao G, Zhang Y, Zhang H, Guo Y, Xu C, Ge D, Gu J.   +6 more
europepmc   +1 more source

The Aging Microenvironment Shapes Angiogenic Remodeling in IBD‐Associated Colorectal Carcinogenesis

Aging Cell, Volume 25, Issue 6, June 2026.
In IBD, chronic inflammation promotes cellular senescence across epithelial, stromal, endothelial, and immune compartments. The resulting SASP drives pathological angiogenesis, vascular dysfunction, hypoxia, and immune suppression, thereby facilitating progression from inflammation to dysplasia and colitis‐associated colorectal cancer.
Ruoshu Duan, Qingyu Chen, Yuan Xu, Ye Yan, Sujing Jiang   +4 more
wiley   +1 more source

Single‐Cell Omics Analysis of Human Basophils Reveals Two Transcriptionally Distinct Populations

Allergy, Volume 81, Issue 6, Page 2059-2068, June 2026.
Integrated single‐cell transcriptomics and large‐scale immunophenotyping reveal the molecular landscape of human basophils. Circulating basophils comprise two transcriptionally distinct populations. A user‐friendly web resource enables interactive exploration of the generated data.
Sofia Papavasileiou, Jiezhen Mo, Daryl Boey, Chenyan Wu, Magnus Tronstad, Lucille Margerie, Remi‐André Olsen, Jörg A. Bachmann, Jing Hui Low, Jocelyn Ong, Lars Heede Blom, Anand Kumar Andiappan, Gunnar Nilsson, Joakim S. Dahlin   +13 more
wiley   +1 more source

Clinical value of combined serum galectin-9 and urine MCP-1 testing for assessment of systemic lupus erythematosus disease activity and early diagnosis of lupus nephritis. [PDF]

Am J Transl Res
Ma F, Ou Y, Liu Y, Ge S.
europepmc   +1 more source

Galectin-3 gene deletion alters lipid profile in healthy and cardiomyopathy mouse hearts

Galectin-3 gene deletion alters lipid profile in healthy and cardiomyopathy mouse ...
WB Zhao (15790577), Mark Ziemann (13101363), G She (13427691), W Wu (7409642), YY Yang (22069490), XJ Du (11181900), PJ Meikle (9856718), K Huynh (9856661), Q Lu (9040523), XL Deng (15768089), T Duong (12018110), XX Hai (22069487), Y Zhang (5998940)   +12 more
core  

Galectin-9 inhibition of the MIF-CD74/CD44 pathway suppresses chronic arthritis. [PDF]

Mol Ther
Li M, Nam MK, Kim JG, Kang J, Park SH, Lee SH, Kim C, Song D, Jin J, Yoo SA, Bucala R, Kim WU.   +11 more
europepmc   +1 more source

Comparison of Proteomic Analysis of Cerebrospinal Fluid From Neurological Patients With and Without Amyotrophic Lateral Sclerosis

Journal of Neurochemistry, Volume 170, Issue 6, June 2026.
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterised by progressive muscle weakness in both bulbar and extremity muscles, leading to a diverse clinical phenotype with motor and non‐motor symptoms. Cerebrospinal fluid (CSF) from sporadic ALS patients were analysed for proteomics content and revealed altered inflammatory and ...
Eleonora Sabetta, Karin Rallmann, Pille Taba, Abigail L. Pfaff, Bal Hari Poudel, Davide Ferrari, Massimo Locatelli, Sulev Kõks, Jonas Bergquist   +8 more
wiley   +1 more source