Results 21 to 30 of about 142,873 (257)

An edge cloud–based body data sensing architecture for artificial intelligence computation

open access: yesInternational Journal of Distributed Sensor Networks, 2019
As various applications and workloads move to the cloud computing system, traditional approaches of processing sensor data cannot be applied. Specifically, tenants may experience incompatibility and unpredictable performance variation due to inefficient ...
TaeYoung Kim, JongBeom Lim
doaj   +1 more source

Introduction: A Literary Studies/Games Studies Conversation [PDF]

open access: yesGames and Culture, 2019
In this special issue of Games and Culture, we present papers originally delivered at the “Literature and Video Games: Beyond Stereotypes” event co-organized by colleagues from the University of St Andrews, the University of Glasgow, and Abertay University.
Hutton, Margaret-Anne, Barr, Matthew
openaire   +4 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

A Study on Visualization of Digital Twin Electric Vehicles Based on Gamification: A Simulation Using Game Engines

open access: yesTehnički Glasnik
This study investigated a methodology for implementing and simulating a digital twin (metaverse) electric vehicle visualization with gamification using a game engine (Unity 3D).
Jung Tae Kim
doaj   +1 more source

Effects of the Design Factors of Skill Training Games on Learning Performance and Emotion: English-Language Typing Games

open access: yesTūzī yǔ dàng’àn xuékān, 2018
Skill training games are one kind of educational games, but they differ from the educational games that aim at promoting cognitive or affective effects.
Chih-Ming Chen   +2 more
doaj   +1 more source

Children of Kubaba: Serious Games, Ritual Toys, and Divination at Iron Age Carchemish

open access: yesReligions, 2022
This paper presents an analysis of a ritual event memorialised on stone reliefs at the ancient city of Carchemish around 800 BC. It is argued that the reliefs represent a ceremony of investiture, in which boys of royal lineage are handed out toys as ...
Alessandra Gilibert
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Scenarios for Revolution in Sid Meier’s Civilization (1991) and Sid Meier’s Colonization (1994)

open access: yesLocus, 2023
This article examines the function and representation of the historical concept of ‘revolution’ in Sid Meier’s Civilization and its offshoot Colonization. Revolution is a central concept in both games, although it has a different character and purpose in
Martijn van der Burg
doaj  

Weibliche Adelsherrschaft und Regentinnenschaft in der Dragon Age-Reihe

open access: yesÖsterreichische Zeitschrift für Geschichtswissenschaften, 2023
BioWare’s Dragon Age series has often been cited as an example for meieval fantasy games being inclusive of women despite their medieval worlds. This article, in contrast, argues that the kingdom of Ferelden constructed by the game is based on the idea ...
Aurelia Brandenburg
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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