Results 41 to 50 of about 13,292,771 (297)

An edge cloud–based body data sensing architecture for artificial intelligence computation

open access: yesInternational Journal of Distributed Sensor Networks, 2019
As various applications and workloads move to the cloud computing system, traditional approaches of processing sensor data cannot be applied. Specifically, tenants may experience incompatibility and unpredictable performance variation due to inefficient ...
TaeYoung Kim, JongBeom Lim
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Chasing the Fugitive on Campus: Designing a Location-based Game for Collaborative Play [PDF]

open access: yes, 2007
We report on our experiences with building and deploying a collaborative location-based mobile game. The Fugitive is a multiplayer game that is played using mobile TabletPCs in a university campus environment.
Jeffrey, Phillip   +6 more
core   +1 more source

“I bet she’s ‘not like other girls’”: Discursive Construction of the Ideal Gaming Woman on r/GirlGamers

open access: yesMedia and Communication
Research on women and hostile behaviour in video games has largely focused on women as victims rather than perpetuators of hostile behaviour. In this study, by utilizing discourse analysis, we examine how women’s hostile behaviour is discussed in the ...
Maria Ruotsalainen, Mikko Meriläinen
doaj   +1 more source

Scenarios for Revolution in Sid Meier’s Civilization (1991) and Sid Meier’s Colonization (1994)

open access: yesLocus, 2023
This article examines the function and representation of the historical concept of ‘revolution’ in Sid Meier’s Civilization and its offshoot Colonization. Revolution is a central concept in both games, although it has a different character and purpose in
Martijn van der Burg
doaj  

Ce que nous savons sur (les) Sciences du jeu : analyse bibliométrique et lexicométrique des articles de la revue (2013-2022)

open access: yesSciences du Jeu, 2023
On its website, Sciences du jeu describes itself as an “international and interdisciplinary journal whose mission is to develop and promote French-speaking researc[h] on play”, “to foster dialogue between social sciences and set off debates on this ...
Fanny Barnabé   +4 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Het spel en de regels. Game studies voor politiek theoretici en cultuurwetenschappers

open access: yesLocus, 2023
Game studies offers numerous starting points for research by political theorists and cultural scholars. Politics is largely a regulated game, with discussion of the rules of the game always part of the political struggle.
Wim de Jong
doaj  

L’approche communicationnelle en études du jeu : un apport des chercheur.se.s de la Faculté de communication de l’UQAM

open access: yesCommuniquer, 2020
Game studies have recently been developed by researchers from different disciplines, each with their own concepts, approaches and methodologies. This article describes how researchers in game studies from the Faculty of Communication of the Université du
Maude Bonenfant   +2 more
doaj   +1 more source

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