Results 61 to 70 of about 13,292,771 (297)
Culture & History Digital Journal, 2020 In “The Idea of a Town: Anthropology of Urban Form” (1976), architecture historian Joseph Rykwert defined six archetypes used in Etruscan rites for the foundation of urban settlements, which continued to be used in Classical Greece and Ancient Rome.
Manuel Sánchez García
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Game Stud., 2016 In the last few years there has been an increase in game scholarship conducted in and focussed on areas outside of Western Europe and North America. This scholarship has been recognized and supported by the establishment of regional research networks and regular regional conferences, and has been collected in edited books and journal special issues ...
Liboriussen, Bjarke, Martin, Paul
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
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A Behavioral Study of 'Noise' in Coordination Games [PDF]
SSRN Electronic Journal, 2014 'Noise' in this study, in the sense of evolutionary game theory, refers to deviations from prevailing behavioral rules. Analyzing data from a laboratory experiment on coordination in networks, we tested 'what kind of noise' is supported by behavioral evidence.
Mäs, Michael, Nax, Heinrich H
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Introducing Mad Studies and Mad Reading to Game Studies
, 2022 The aim of this paper is to introduce and develop mad studies as a theory and mad reading as a method for examining representations of madness in games.
Rodéhn, Cecilia,
core
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Journal of Digital Media & InteractionThis article offers a critical reading of the tensions between two contemporary regimes of game design: on the one side, seamless game design, which aims to smooth out the gaming experience by eliminating any form of rupture; on the other, a set of ...
Brice Roy
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Jeux vidéo : entreprises numériques au croisement du ludique et du narratif
Transatlantica, 2013 This article is concerned with the evolution of the narrative tools implemented by different development studios over the past five decades. Its goal is to raise the question of the evolution of the nature of stories, and of the space devoted to these ...
Rémi Cayatte
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GameSound, Quantitative Games Analysis, and the Digital Humanities
Digital Studies, 2020 This article relates to the 2018 CSDH/SCHN conference proceedings. This paper outlines Michael Iantorno’s and Melissa Mony’s experiences with quantitative game analysis by summarizing the first year of development of the prototype ludomusicological ...
Michael Iantorno
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Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source