Results 71 to 80 of about 148,804 (264)

Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi   +6 more
wiley   +1 more source

Revisiting violent videogames research: Game studies perspectives on aggression, violence, immersion, interaction, and textual analysis [PDF]

open access: yesDigital Culture & Education, 2009
Thus far, the bulk of effects research on violent video games demon-strates troubling correlations between playing violent video games and increases in (or primers for) aggressive behavior, which suggests that overall, violent video games may be ...
Kyle Kontour
doaj  

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab   +19 more
wiley   +1 more source

Looking for Cosy in All the Wrong Places. Cosiness and Tamed Sublime of "No Man’s Sky"

open access: yesReplay
In this article, I argue that some games may elicit cosy sentiments even if they are centred on a premise not usually associated with cosiness – for example the infinity of the universe.
Tomasz Gnat
doaj   +1 more source

High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello   +5 more
wiley   +1 more source

Comment pense le jeu vidéo ?

open access: yesConserveries Mémorielles, 2018
Videogames are interactive works, which means that their meaning is actualized when the software is played. With the interactive loop, the player contributes to reorganize in an always new way the different narrative elements, but it is above all the ...
Martin RINGOT
doaj  

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights From a Large International Sicca Registry

open access: yesArthritis Care &Research, EarlyView.
Objective The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögren's International Collaborative Clinical Alliance (SICCA) cohort. Methods We performed a retrospective analysis examining 16 ocular symptoms (most graded 0–4) and artificial tear (AT) use (graded 0–3) as predictors of DED signs (abnormal ocular ...
Pragnya R. Donthineni   +7 more
wiley   +1 more source

Technological Bodies: Artificial Intelligence as Friday in Portal and Halo Infinite

open access: yesNJES: Nordic Journal of English studies
Artificial intelligence characters provide a unique perspective on the discussion of Friday figures and issues of Otherness and Othering as they relate to the body.
Sarah Faber
doaj   +1 more source

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

open access: yesArthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa   +3 more
wiley   +1 more source

Game Studies

open access: yes, 2014
Reviews: GamesCoop, Theorien des Computerspiels zur Einführung, Hamburg (Junius) 2012. Stephan Günzel, Egoshooter. Das Raumbild des Computerspiels, Frankfurt / New York (Campus Verlag) 2013. Miguel Sicart, Beyond Choices. The Design of Ethical Gameplay, Cambridge, Mass. (MIT Press) 2013.
openaire   +2 more sources

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