Results 101 to 110 of about 95,987 (292)

T10B9 monoclonal antibody: A short-acting nonstimulating monoclonal antibody that spares γδ T-cells and treats and prevents cellular rejection

Drug Design, Development and Therapy, 2009
Thomas H Waid1, John S Thompson1, Maria Siemionow2, Stephen A Brown1 1Department of Internal Medicine, University of Kentucky, Lexington, Kentucky, USA; 2Cleveland Clinic, Cleveland, Ohio, USAAbstract: T10B9.1A-31/MEDI-500 is a ...
Thomas H Waid, John S Thompson, Maria Siemionow, Stephen A Brown   +3 more
doaj  

Human gamma delta T cells induce dendritic cell maturation.

, 2002
gamma delta T cells are known to be involved in the innate immune defenses against infectious microorganisms. Herein, we considered that gamma delta T cells could also influence adaptative immunity by interacting with dendritic cells (DC) in the early ...
Poupot, Rémy, Goldman, Michel, Ismaili, Jamila, Olislagers, Véronique, Fournié, Jean-Jacques   +4 more
core  

Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation

Advanced Healthcare Materials, EarlyView.
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad, Natasha K. Hunt, Srujan Singh, Kelly B. Seims, Yingjie Wu, E. Thomas Pashuck, Warren L. Grayson, Lesley W. Chow   +7 more
wiley   +1 more source

Role of innate T cells in anti-bacterial immunity

Frontiers in Immunology, 2015
Innate T cells are a heterogeneous group of αβ and γδ T cells that respond rapidly (
Yifang eGao, Anthony P Williams, Anthony P Williams   +2 more
doaj   +1 more source

Photothermal‐Activated Antibacterial Amyloid‐Polyphenol‐Iron Hydrogels for Synergistic Wound Healing

Advanced Healthcare Materials, EarlyView.
We report a thermally triggered supramolecular hydrogel (LTFe) formed by Fe3+ and tannic acid on lysozyme amyloid fibrils. Fe3+ enables rapid gelation and photothermal transduction with an efficiency of 88.56%. The LTFe hydrogel exhibits excellent biocompatibility, potent antibacterial activity against E. coli and S.
Di Wu, Jiangtao Zhou, Yang Shen, Qiyao Sun, Tong Li, Xiaoyang Zou, Bin Liu, Hongshan Liang, Raffaele Mezzenga   +8 more
wiley   +1 more source

Key players of immunosuppression in epithelial malignancies: Tumor‐infiltrating myeloid cells and γδ T cells

Cancer Reports
Background The tumor microenvironment of solid tumors governs the differentiation of otherwise non‐immunosuppressive macrophages and gamma delta (γδ) T cells into strong immunosuppressors while promoting suppressive abilities of known immunosuppressors ...
Baishali Tamuli, Sakshi Sharma, Meena Patkar, Subir Biswas   +3 more
doaj   +1 more source

The emerging roles of gamma-delta T cells in tissue inflammation in experimental autoimmune encephalomyelitis

Frontiers in Immunology, 2016
γδ (gamma delta) T cells, a small population of unconventional T cells, have been seen in central nervous system (CNS) lesions of multiple sclerosis (MS) patients, but their function in disease activity is not clearly understood.
Amit eAwasthi, Sakshi eMalik, Muzamil Yaqub Want   +2 more
doaj   +1 more source

Stepwise On‐Surface Synthesis and Transformations of Two‐Dimensional Covalent Organic Frameworks by Controlled Thermal Stimuli

Advanced Materials, EarlyView.
The seminal transformation of a 2D‐COF (SURFCOF‐IMDEA1) into a 2D porous COF (SURFCOF‐IMDEA2) on Au(111) by a sequential C‐C coupling and ladderization triggered by thermal annealing steps at increasing temperatures is reported. Abstract The development of covalent organic frameworks (COFs) is currently a primary objective in materials science, taking ...
Ana Barragán, Elena Pérez‐Elvira, Diego J. Vicent, Marco Lozano, Diego Soler‐Polo, Koen Lauwaet, José M. Gallego, Rodolfo Miranda, José I. Urgel, Pavel Jelínek, Nazario Martín, David Écija   +11 more
wiley   +1 more source

Distinct subpopulations of gamma delta T cells are present in normal and tumor-bearing human liver

, 2004
gammadelta cells are thought to mediate immune responses at epithelial surfaces. We have quantified and characterized hepatic and peripheral blood gammadelta T cells from 11 normal and 13 unresolved tumor-bearing human liver specimens. gammadelta T cells
Norris, Suzanne, Kenna, T, Golden-Mason, Lucy, Tony Kenna, O'Farrelly, C, Norris, S, Hegarty, JE, John E. Hegarty, Suzanne Norris, Doherty, DG, Derek G. Doherty, Cliona O'Farrelly, O'Farrelly, Cliona, Golden-Mason, L, Hegarty, John E., Lucy Golden-Mason, Kenna, Tony, Doherty, Derek G.   +17 more
core   +1 more source

Opportunities of Semiconducting Oxide Nanostructures as Advanced Luminescent Materials in Photonics

Advanced Materials, EarlyView.
The review discusses the challenges of wide and ultrawide bandgap semiconducting oxides as a suitable material platform for photonics. They offer great versatility in terms of tuning microstructure, native defects, doping, anisotropy, and micro‐ and nano‐structuring. The review focuses on their light emission, light‐confinement in optical cavities, and
Ana Cremades, Pedro Hidalgo, David Maestre, Ruth Martínez‐Casado, Emilio Nogales, Beatriz Rodríguez, G. Cristian Vásquez, Bianchi Méndez   +7 more
wiley   +1 more source