Results 81 to 90 of about 95,987 (292)

EphA2 and phosphoantigen-mediated selective killing of medulloblastoma by γδT cells preserves neuronal and stem cell integrity

OncoImmunology
Medulloblastoma (MB) is a pediatric brain tumor that develops in the cerebellum, representing one of the most common malignant brain cancers in children. Standard treatments include surgery, chemotherapy, and radiation, but despite a 5-y survival rate of
Lola Boutin, Mingzhi Liu, Julie Déchanet Merville, Oscar Bedoya-Reina, Margareta T Wilhelm   +4 more
doaj   +1 more source

Engineering Approaches in Human Gamma Delta T Cells for Cancer Immunotherapy

Frontiers in Immunology, 2018
Sharing both innate and adaptive immune properties, γδT cells are attractive candidates for cellular engineering. As the cancer immunotherapy field becomes increasingly busy, orthogonal approaches are required to drive advancement.
Jonathan Fisher, John Anderson
doaj   +1 more source

3D Printing Innovations in Polymeric Porous and Patterned Architecture

Advanced Functional Materials, EarlyView.
Polymeric foams occupy a unique structural space between dense solids and open networks, where engineered void fraction governs mechanical compliance, thermal resistance, and mass transport. Additive manufacturing now enables precise spatial control over cellular architecture, unlocking designer foam structures across applications spanning crash ...
Dhanush Patil, Sri Vaishnavi Thummalapalli, Clarissa Westover, Arunachalam Ramanathan, M. Taylor Sobzcak, Roumika Patil, Qixuan Xiang, Tiantian Li, Sui Yang, Timothy E. Long, Hongyue Sun, Xianqiao Wang, Yang Liu, Kenan Song   +13 more
wiley   +1 more source

The immunobiology of human hepatic gamma delta T cells [PDF]

, 2018
The liver contains a number of tissue-associated lymphocyte populations, of which many have been implicated in the pathogenesis of chronic liver diseases.
Hunter, Stuart
core  

Analysis of the Effector Functions of Vδ2 γδ T Cells and NK Cells against Cholangiocarcinoma Cells [PDF]

Cholangiocarcinoma (CCA) is a rare disease characterized by malignant cells derived from the epithelial cells of the biliary duct system. Despite extensive treatments, the prognosis for CCA remains poor, emphasizing the critical need for the development ...
Inthuon Kulma, Kesara Na-Bangchang, Carvallo, Herrera Andrea, Hiroshi Mukae, Na-Bangchang, Kesara, Yoshimasa Tanaka, Ndubuisi, Ifeanyi Theodora, Haruki Okamura, Kulma, Inthuon, Iwasaki, Masashi, Morita, Craig T., Masashi Iwasaki, Craig T. Morita, Andrea Carvallo Herrera, Mukae, Hiroshi, Ifeanyi Theodora Ndubuisi, Okamura, Haruki, Hiromi Tomono, Tanaka, Yoshimasa, Tomono, Hiromi   +19 more
core   +1 more source

Resolving the Cu(bdc) Conundrum: Identifying Non‐Porous Packing of Prototypical Coordination‐Network Thin Films Combining Advanced Diffraction Techniques and Computational Modelling

Advanced Functional Materials, EarlyView.
Solution‐processed Cu(bdc) forms prototypical MOF thin films for which a multitude of not fully satisfactory structural models have been suggested. Combining rotating grazing‐incidence diffraction and X‐ray reflectivity on two complementary samples with density‐functional theory, we first discard the previously suggested models and then identify a non ...
Narges Taghizade, Mario Fratschko, Robbin Steentjes, Mercedes Linares‐Moreau, Paolo Falcaro, Christof Wöll, Roland Resel, Egbert Zojer   +7 more
wiley   +1 more source

Pan-cancer γδ TCR analysis uncovers clonotype diversity and prognostic potential

Cell Reports Medicine
Summary: Gamma-delta T cells (γδ T cells) play a crucial role in both innate and adaptive immunity within tumors, yet their presence and prognostic value in cancer remain underexplored. This study presents a large-scale analysis of γδ T cell receptor (γδ
Xiaoqing Yu, Li Song, Ling Cen, Biwei Cao, Ranran Tao, Yuanyuan Shen, Daniel Abate-Daga, Paulo C. Rodriguez, Jose R. Conejo-Garcia, Xuefeng Wang   +9 more
doaj   +1 more source

Gamma delta T cells recognize haptens and mount a hapten-specific response

eLife, 2014
The ability to recognize small organic molecules and chemical modifications of host molecules is an essential capability of the adaptive immune system, which until now was thought to be mediated mainly by B cell antigen receptors.
Xun Zeng, Christina Meyer, Jun Huang, Evan W Newell, Brian A Kidd, Yu-Ling Wei, Yueh-hsiu Chien   +6 more
doaj   +1 more source

Designed Lewis Acid–Base Passivation for High Performance Perovskite Solar Cells

Advanced Functional Materials, EarlyView.
ABSTRACT Silicon's high cost and long energy payback time remain major barriers to the global expansion of solar power. In contrast, metal–halide perovskites offer abundant, solution‐processable absorbers, and have achieved efficiencies of 25%–30%, positioning them as strong competitors to silicon.
Afna Manaf, Hiba Shahulhameed, Bhabani Sankar Swain, Shengzhong (Frank) Liu, Adel Najar   +4 more
wiley   +1 more source

Research progress on V delta 1+ T cells and their effect on pathogen infection [PDF]

PeerJ
The ongoing high occurrence of harmful infectious diseases significantly threatens human health. Existing methods used to control such diseases primarily involve targeting the pathogens, usually neglecting the vital role of host factors in disease ...
Yuxia Li, Yanfei Liu, Xiaoxiao Bu, Yuanyuan Qin, Yanyan Zhang   +4 more
doaj   +2 more sources