Results 91 to 100 of about 6,064 (187)

A Mixed Covalent–Supramolecular Interpenetrated Copper–Phosphonate Network

Zeitschrift für anorganische und allgemeine Chemie, EarlyView.
Zigzag Cu–bisphosphonate double strands are connected by dipyridyl linkers to two‐dimensional layers which are organized via hydrogen bonds into a three‐dimensional, two‐fold interpenetrated hydrogen‐bonded framework. A novel copper‐based coordination network [Cu(1,4‐DPB)(H2NBP)] was synthesized via a hydrothermal process using 1,4‐di(pyridin‐4‐yl ...
Marcus N. A. Fetzer, Tobias Heinen, Nabil Assahub, Christoph Janiak   +3 more
wiley   +1 more source

Pressure Pulses Generated by Wire‐Guided Discharges in Water

High Voltage, EarlyView.
ABSTRACT The hydrodynamic characteristics of underwater wire‐guided discharges and their relationships with the wire length and pulsed circuit parameters are not fully understood. In this paper wire‐guided discharges using wires of length 3, 5 and 7 cm and diameter of 0.05 mm have been investigated. The energy available to the discharges was 162.3 J at
Yifan Chai, Igor Timoshkin, Martin J. Given, Scott J. MacGregor   +3 more
wiley   +1 more source

Impact of G‐CSF on Donor TCR Clonal Diversity and T Cell Function During Donor HSC Mobilisation

Cell Proliferation, EarlyView.
In this study, we found that G‐CSF mobilisation caused a reduction in TCR clonal diversity and down‐regulation of T‐cell function in donors. This may be one of the reasons for the low incidence of GVHD mediated by G‐CSF after allo‐HSCT. Source: Created in BioRender. Li https://BioRender.com/otownki.
Xinye Li, Zhixi Chen, Jie Chen, Xingwei Zhang, Jiamian Zheng, Zirui Liu, Meixue Pan, Yue Li, Bo Yu, Shaohua Chen, Jing Lai, Xianfeng Zha, Liye Zhong, Yikai Zhang, Yangqiu Li   +14 more
wiley   +1 more source

Inflammation and mechanical force‐induced bone remodeling

Periodontology 2000, EarlyView.
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon, Xin Huang, Leticia Rojas Cortez, Puttipong Sripinun, Jung‐me Lee, Julie J. Hong, Dana T. Graves   +6 more
wiley   +1 more source

CD16 and CD57 expressing gamma delta T cells in acute HIV-1 infection are associated with the development of neutralization breadth.

PLoS Pathogens
New HIV vaccine approaches are focused on eliciting broadly neutralizing antibodies. We characterized early gamma-delta (γδ) T cell responses starting from pre-acquisition and during acute HIV infection (AHI) in participants previously characterized for ...
Gina L Griffith, Kawthar Machmach, Ningbo Jian, Dohoon Kim, Margaret C Costanzo, Matthew Creegan, Isabella Swafford, Gautam Kundu, Lauren Yum, Jessica S Bolton, Lauren Smith, Bonnie M Slike, Elke S Bergmann-Leitner, Rasmi Thomas, Nelson L Michael, Julie A Ake, Leigh Anne Eller, Merlin L Robb, Samantha M Townsley, Shelly J Krebs, Dominic Paquin-Proulx, RV217 Study Group   +21 more
doaj   +1 more source

Ligand-induced segregation from large cell-surface phosphatases is a critical step in γδ TCR triggering

Cell Reports
Summary: Gamma/delta (γδ) T cells are unconventional lymphocytes that recognize diverse ligands via somatically recombined T cell antigen receptors (γδ TCRs). The molecular mechanism by which ligand recognition initiates γδ TCR signaling, a process known
Fenglei Li, Sobhan Roy, Jacob Niculcea, Keith Gould, Erin J. Adams, P. Anton van der Merwe, Kaushik Choudhuri   +6 more
doaj   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Use of monoclonal antibodies to study alloreactivity and T cell development in Xenopus [PDF]

, 1993
This study investigated T-cell surface antigenic changes in the spleen of Xenopus following in vivo and in vitro allergenic challenge, using novel mouse monoclonal antibodies (mAb's) against all T cells (CDS), the putative ɑβ-T cell receptor (TCR), the ...
Paul, Tina
core  

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Mapping of γ/δ T cells reveals Vδ2+ T cells resistance to senescenceResearch in context

EBioMedicine, 2019
Background: Immune adaptation with aging is a major of health outcomes. Studies in humans have mainly focus on αβ T cells while γδ T cells have been neglected despite their role in immunosurveillance.
Weili Xu, Gianni Monaco, Eleanor Huijin Wong, Wilson Lek Wen Tan, Hassen Kared, Yannick Simoni, Shu Wen Tan, Wilson Zhi Yong How, Crystal Tze Ying Tan, Bernett Teck Kwong Lee, Daniel Carbajo, Srinivasan K.G., Ivy Chay Huang Low, Esther Wing Hei Mok, Shihui Foo, Josephine Lum, Hong Liang Tey, Wee Ping Tan, Michael Poidinger, Evan Newell, Tze Pin Ng, Roger Foo, Arne N. Akbar, Tamas Fülöp, Anis Larbi   +24 more
doaj   +1 more source