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Clinical applications of gamma delta T cells with multivalent immunity [PDF]
Frontiers in Immunology, 2014 Gamma delta T cells hold promise for adoptive immunotherapy because of their reactivity to bacteria, viruses, and tumors. However, these cells represent a small fraction (1-5%) of the peripheral T-cell pool and require activation and propagation to ...
Drew C Deniger +2 more
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Potential of gamma/delta T cells for solid tumor immunotherapy [PDF]
Frontiers in ImmunologyGamma/delta T (γδ T)cells possess a unique mechanism for killing tumors, making them highly promising and distinguished among various cell therapies for tumor treatment.
Dantong Zhu +9 more
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Contemplating Dichotomous Nature of Gamma Delta T Cells for Immunotherapy [PDF]
Frontiers in Immunology, 2022 γδ T cells are unconventional T cells, distinguished from αβ T cells in a number of functional properties. Being small in number compared to αβ T cells, γδ T cells have surprised us with their pleiotropic roles in various diseases.
Jaydeep Bhat +2 more
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Perforins Expression by Cutaneous Gamma Delta T Cells [PDF]
Frontiers in Immunology, 2020 Gamma delta (GD) T cells are an unconventional T cell type present in both the epidermis and the dermis of human skin. They are critical to regulating skin inflammation, wound healing, and anti-microbial defense.
Katelyn O'Neill +3 more
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Special Issue “Gamma Delta T Cells in Immune Response against Viruses” [PDF]
Viruses, 2022 γδ T cells are members of ‘unconventional’ T cells that combine the properties of adaptive T lymphocytes and innate cells such as NK cells [...]
Eric Champagne
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Gamma Delta T Cells and Their Pathogenic Role in Psoriasis [PDF]
Frontiers in Immunology, 2021 γδT cells are an unconventional population of T lymphocytes that play an indispensable role in host defense, immune surveillance, and homeostasis of the immune system. They display unique developmental, distributional, and functional patterns and rapidly
Cong Qi +7 more
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What Can Gamma Delta T Cells Contribute to an HIV Cure? [PDF]
Frontiers in Cellular and Infection Microbiology, 2020 Elimination of the latent HIV reservoir remains a major barrier to achieving an HIV cure. In this review, we discuss the cytolytic nature of human gamma delta T cells and highlight the emerging evidence that they can target and eliminate HIV-infected T ...
Jennifer A. Juno +3 more
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Gamma Delta T Cells and Their Involvement in COVID-19 Virus Infections [PDF]
Frontiers in Immunology, 2021 The global outbreak of the SARS-Cov-2 virus in 2020 has killed millions of people worldwide and forced large parts of the world into lockdowns. While multiple vaccine programs are starting to immunize the global population, there is no direct cure for ...
Georg von Massow +3 more
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Gamma delta T cells and their immunotherapeutic potential in cancer [PDF]
Biomarker ResearchGamma–delta (γδ) T cells are a unique subset of T lymphocytes that play diverse roles in immune responses, bridging innate and adaptive immunity. With growing interest in their potential for cancer immunotherapy, a comprehensive and inclusive exploration
Stephen G. Cieslak, Reza Shahbazi
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Gamma Delta T Cells (γδ T Cells) in Health and Disease: In Memory of Professor Wendy Havran [PDF]
Cells, 2020 Gamma delta (γδ) T cells are a small subset of CD3-positive T cells in the peripheral blood but occur at increased frequency in mucosal tissues [...]
Dieter Kabelitz
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