Results 11 to 20 of about 95,987 (292)
Gamma Delta T Cells (γδ T Cells) in Health and Disease: In Memory of Professor Wendy Havran [PDF]
Cells, 2020 Gamma delta (γδ) T cells are a small subset of CD3-positive T cells in the peripheral blood but occur at increased frequency in mucosal tissues [...]
Dieter Kabelitz
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Clinical applications of gamma delta T cells with multivalent immunity
Frontiers in Immunology, 2014 Gamma delta T cells hold promise for adoptive immunotherapy because of their reactivity to bacteria, viruses, and tumors. However, these cells represent a small fraction (1-5%) of the peripheral T-cell pool and require activation and propagation to ...
Drew C Deniger +2 more
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Human peripheral CD4+ Vdelta1+ gamma delta T cells can develop into alpha beta T cells
Frontiers in Immunology, 2014 The lifelong generation of alpha beta T cells enables us to continuously build immunity against pathogens and malignancies despite the loss of thymic function with age. Consequently, alpha beta T-cell development has to occur independently of the thymus.
Hendrik eZiegler +6 more
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Plasticity of gamma delta T cells: impact on the anti-tumor response
Frontiers in Immunology, 2014 The tumor immune microenvironment contributes to tumor initiation, progression and response to therapy. Among the immune cell subsets that play a role in the tumor microenvironment, innate-like T cells that express T cell receptors composed of gamma and ...
Virginie eLafont +7 more
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Gamma delta T cells in hepatocellular carcinoma: Sunrise of new therapy based on Vδ2 T cells? [PDF]
Clinical and Translational Medicine, 2022 Zuzana Macek Jilkova
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Activated Chicken Gamma Delta T Cells Are Involved in Protective Immunity against Marek's Disease. [PDF]
Viruses, 2023 Gamma delta (γδ) T cells play a significant role in the prevention of viral infection and tumor surveillance in mammals. Although the involvement of γδ T cells in Marek’s disease virus (MDV) infection has been suggested ...
Matsuyama-Kato A +13 more
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Gamma‐delta t‐cell lymphomas [PDF]
European Journal of Haematology, 2014 AbstractGamma‐delta T‐cell lymphomas are aggressive and rare diseases originating from gamma‐delta lymphocytes. These cells, which naturally play a role in the innate, non‐specific immune response, develop from thymic precursor in the bone marrow, lack the major histocompatibility complex restrictions and can be divided into two subpopulations: Vdelta1,
Foppoli M., Ferreri A. J. M.
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Frontiers in Immunology, 2022 The γδT cell subset of peripheral lymphocytes exhibits potent cancer antigen recognition independent of classical peptide MHC complexes, making it an attractive candidate for allogeneic cancer adoptive immunotherapy.
Gabrielle M. Ferry +7 more
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Frontiers in Immunology, 2021 The WC1 cell surface family of molecules function as hybrid gamma delta (γδ) TCR co-receptors, augmenting cellular responses when cross-linked with the TCR, and as pattern recognition receptors, binding pathogens.
Alexandria Gillespie +7 more
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Five layers of receptor signalling in γδ T cell differentiation and activation
Frontiers in Immunology, 2015 The contributions of gamma-delta T cells to immunity to infection or tumours critically depend on their activation and differentiation into effectors capable of secreting cytokines and killing infected or transformed cells.
Sérgio T. Ribeiro +2 more
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