Gamma Delta T Cell Therapy for Cancer: It Is Good to be Local
Frontiers in Immunology, 2018 Human gamma delta T cells have extraordinary properties including the capacity for tumor cell killing. The major gamma delta T cell subset in human beings is designated Vγ9Vδ2 and is activated by intermediates of isoprenoid biosynthesis or ...
C. David Pauza +6 more
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Role of innate T cells in anti-bacterial immunity [PDF]
Frontiers in Immunology, 2015 Innate T cells are a heterogeneous group of αβ and γδ T cells that respond rapidly (
Yifang eGao +2 more
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International Journal of Nanomedicine, 2019 Li Lin,1,2,* Junyi He,2,* Jiawei Li,2 Yan Xu,2 Jingxia Li,2 Yangzhe Wu1,2 1Zhuhai Precision Medical Center, Zhuhai People’s Hospital, Zhuhai Hospital Affiliated with Jinan University, Jinan University, Zhuhai, Guangdong 519000, People’s ...
Lin L, He J, Li J, Xu Y, Li J, Wu Y
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Evidence for clonal selection of gamma/delta T cells in response to a human pathogen. [PDF]
Journal of Experimental Medicine, 1991 T cells bearing gamma/delta antigen receptors comprise a resident population of intraepithelial lymphocytes in organs such as skin, gut, and lungs, where they are strategically located to contribute to the initial defense against infection.
Band, H +7 more
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Gamma delta T cells recognize haptens and mount a hapten-specific response
eLife, 2014 The ability to recognize small organic molecules and chemical modifications of host molecules is an essential capability of the adaptive immune system, which until now was thought to be mediated mainly by B cell antigen receptors.
Xun Zeng +6 more
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DPP4-inhibition reduces pro-inflammatory cytokine production by alpha-beta and gamma-delta T cells in vitro and in the biliary atresia mouse model. [PDF]
Sci RepWilde AC +7 more
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Gamma delta T cells in hepatocellular carcinoma: Sunrise of new therapy based on Vδ2 T cells? [PDF]
Clinical and Translational Medicine, 2022 Zuzana Macek Jilkova
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Genome-Wide DNA Methylation Profiling in CD8 T-Cells and Gamma Delta T-Cells of Asian Indian Patients With Takayasu Arteritis. [PDF]
Front Cell Dev Biol, 2022 Kabeerdoss J +5 more
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Gamma‐delta t‐cell lymphomas [PDF]
European Journal of Haematology, 2014 AbstractGamma‐delta T‐cell lymphomas are aggressive and rare diseases originating from gamma‐delta lymphocytes. These cells, which naturally play a role in the innate, non‐specific immune response, develop from thymic precursor in the bone marrow, lack the major histocompatibility complex restrictions and can be divided into two subpopulations: Vdelta1,
Foppoli M., Ferreri A. J. M.
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Cutaneous gamma/delta T‐cell lymphoma [PDF]
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2009 SummaryOnly 40 cases of primary cutaneous gamma/delta T‐cell lymphoma (GD‐TCL) have been described. GD‐TCL was included as a provisional entity in the WHO‐EORTC classification of cutaneous lymphomas in 2005.GD‐TCL often failed to respond to polychemotherapy and radiation therapy and have a poor prognosis with a mean survival of only 15 months.
Richard, Koch +5 more
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