Results 31 to 40 of about 182,849 (338)

Apoptosis of Fashigh CD4+ synovial T cells by borrelia-reactive Fas-ligand(high) gamma delta T cells in Lyme arthritis [PDF]

, 1996
The function of the minor subset of T lymphocytes bearing the gamma delta T cell antigen receptor is uncertain. Although some gamma delta T cells react to microbial products, responsiveness has only rarely been demonstrated toward a bacterial antigen ...
Alderson, Alderson, Augustin, Bellgrau, Born, Brennan, Carding, Cooper, David Lynch, David Wilson, De Libero, Emoto, French, Gavrieli, Goodman, Griffith, Groh, Haas, Haregewoi, Holoshitz, Huber, Janis, Jurg Tschopp, Kagi, Karen Roessner, Leonard H. Sigal, Lowin, Mariani, McMenamin, Michael S. Vincent, Modlin, Morita, Mukasa, Nagata, O'Brien, Parker, Pelegri, Peterman, Ralph C. Budd, Roessner, Rouvier, Rust, Sgorc, Sheldon M. Cooper, Spencer, Suda, Tanaka, Wright, Yssel   +48 more
core   +2 more sources

Human peripheral CD4+ Vdelta1+ gamma delta T cells can develop into alpha beta T cells

Frontiers in Immunology, 2014
The lifelong generation of alpha beta T cells enables us to continuously build immunity against pathogens and malignancies despite the loss of thymic function with age. Consequently, alpha beta T-cell development has to occur independently of the thymus.
Hendrik eZiegler, Christian eWelker, Marco eSterk, Jan eHaarer, Hans-Georg eRammensee, Rupert eHandgretinger, Karin eSchilbach   +6 more
doaj   +1 more source

Synthesis of analogues of (E)-1-hydroxy-2-methylbut-2-enyl 4-diphosphate, an isoprenoid precursor and human γδ T cell activator [PDF]

, 2008
(E)-1-Hydroxy-2-methyl-but-2-enyl 4-diphosphate (HMBPP) is an intermediate in the non-mevalonate pathway for the biosynthesis of isoprenoids and also serves as a very strong activator of human gamma delta T cells expressing V gamma 9V delta 2 receptors ...
Jomaa, Hassan, Lacey, Carl Jeffrey, Röhrich, Rene C, Van Calenbergh, Serge, Van Hoof, Steven, Wiesner, Jochen   +5 more
core   +2 more sources

γδ T cells in HIV Disease: Past, Present and Future

Frontiers in Immunology, 2015
Human immunodeficiency virus type 1 (HIV) dysregulates γδ T cells as part of an immune evasion mechanism. Nearly 3 decades of research defined the effects of HIV on γδ T cells and how this impacts disease.
C. David ePauza, Bhawna ePoonia, Haishan eLi, Cristiana eCairo, Suchita eChaudhry   +4 more
doaj   +1 more source

Non-V delta 2 gamma delta T lymphocytes as effectors of cancer immunotherapy [PDF]

, 2014
Gamma delta T cells (γδT) are potent mediators of antitumor cytotoxicity and have shown promising efficacy in early phase clinical trials. Most is known about the tumoricidal properties of cells bearing the Vδ2 T cell receptor chain, but recent studies ...
Anderson, J, Fisher, J, Gustafsson, K, Kramer, AM   +3 more
core   +1 more source

Sheep TRD@ locus consists of a large number of TRDV elements

Italian Journal of Animal Science, 2011
The T cell receptor (TcR) expressed on mature T lymphocytes is a disulphidelinked heterodimer composed of alpha and beta or gamma and delta glycoprotein subunits.
S. Ciccarese, S. Massari, G. Vonghia, A. Caputi Jambrenghi, D. Pagliarulo, R. Antonacci, L. Del Faro   +6 more
doaj   +1 more source

Climate change, in the framework of the constructal law [PDF]

, 2011
Here we present a simple and transparent alternative to the complex models of Earth thermal behavior under time-changing conditions. We show the one-to-one relationship between changes in atmospheric properties and time-dependent changes in temperature ...
Alberton, Bruna, Almeida, Jurandy, Miranda, Waner O., Morellato, Leonor Patricia C., Santos, Jefersson A. dos, Torres, Ricardo da S.   +5 more
core   +1 more source

Mycobacterium tuberculosis promotes Th17 expansion via regulation of human dendritic cells toward a high CD14 and low IL-12p70 phenotype that reprograms upon exogenous IFN-γ. [PDF]

, 2014
Item does not contain fulltextThe capacity to develop protective immunity against mycobacteria is heterogeneously distributed among human beings, and it is currently unknown why the initial immune response induced against Mycobacterium tuberculosis (Mtb)
Acosta-Rodriguez, Agrawal, Bakdash, Bazil, Bazil, Bratke, Chackerian, Chen, Cheong, Chu, Cohn, Demedts, Desjardins, Evans, Fujii, Gautier, Geijtenbeek, Gerosa, Giacomini, Harding, Henderson, Hoene, Hsieh, Ishikawa, Iwasaki, Janne Marie Laursen, Jiao, Jonas Nørskov Søndergaard, Jung, Lai, Lauener, Lisbeth Buus Rosholm, Lucas, Martin, Nathan, Nathan, Nestle, Nigou, Ní Cheallaigh, Owaki, Ramakrishnan, Redford, Russell, Sallusto, Schreiber, Serbina, Susanne Brix, Søndergaard, Tailleux, Tailleux, Torrado, Trinchieri, Uehori, Underhill, Van der Aar, Van Haarst, van Haarst, Varol, Wilson, Winslow, Wolf, World Health Organization, Zanoni, Zenaro   +63 more
core   +1 more source

Hepatosplenic Gamma/DeltaT-Cell Lymphoma Masquerading as Alcoholic Hepatitis and Methadone Withdrawal

Case Reports in Gastroenterology, 2007
Hepatosplenic gamma/delta T-cell lymphoma is a rare neoplasm of mature gamma/delta T-cells with sinusoidal infiltration of spleen, liver, and bone marrow.
H.A. Lopez Morra, S.N. Fine, G. Dickstein   +2 more
doaj   +1 more source

Pig peripheral blood mononuclear leucocyte subsets are heritable and genetically correlated with performance [PDF]

, 2008
Indicator traits used to select pigs for increased resistance to infection or improved health must be heritable and, preferably, be associated with improved performance.
Ahmadi, Cheeseman, Chen, Clapperton, Clapperton, Clapperton, Davis, de Haan, Denham, Denyer, Duarte, E.J. Glass, Edfors-Lilja, Edfors-Lilja, Eurell, Evans, Galina-Pantoja, Gheorgiou, Gilmour, Grellner, Hall, Hall, Haverson, Henryon, Henryon, Jayagopala Reddy, Joling, Lee, Lodoen, Loeffen, Luhtala, Lyons, M. Clapperton, Mallard, Morrison, Myrick, Ober, O’Connor, Pallarés, Parra, Pedrini, Petersen, Poppe, Regula, Roberts, S.C. Bishop, Saalmuller, Segalés, Snowder, Spurlock, Tecles, Thacker, Wonigeit, Yang, Zuckermann   +54 more
core   +1 more source