Results 71 to 80 of about 250 (105)

Adaptive Immunity in Marsupials

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 9, Page 913-932, November 2026.
Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol, Hayley J. Stannard, Julie M. Old   +2 more
wiley   +1 more source

CD16 and CD57 expressing gamma delta T cells in acute HIV-1 infection are associated with the development of neutralization breadth.

PLoS Pathogens
New HIV vaccine approaches are focused on eliciting broadly neutralizing antibodies. We characterized early gamma-delta (γδ) T cell responses starting from pre-acquisition and during acute HIV infection (AHI) in participants previously characterized for ...
Gina L Griffith, Kawthar Machmach, Ningbo Jian, Dohoon Kim, Margaret C Costanzo, Matthew Creegan, Isabella Swafford, Gautam Kundu, Lauren Yum, Jessica S Bolton, Lauren Smith, Bonnie M Slike, Elke S Bergmann-Leitner, Rasmi Thomas, Nelson L Michael, Julie A Ake, Leigh Anne Eller, Merlin L Robb, Samantha M Townsley, Shelly J Krebs, Dominic Paquin-Proulx, RV217 Study Group   +21 more
doaj   +1 more source

Ligand-induced segregation from large cell-surface phosphatases is a critical step in γδ TCR triggering

Cell Reports
Summary: Gamma/delta (γδ) T cells are unconventional lymphocytes that recognize diverse ligands via somatically recombined T cell antigen receptors (γδ TCRs). The molecular mechanism by which ligand recognition initiates γδ TCR signaling, a process known
Fenglei Li, Sobhan Roy, Jacob Niculcea, Keith Gould, Erin J. Adams, P. Anton van der Merwe, Kaushik Choudhuri   +6 more
doaj   +1 more source

Gap‐Free Information Transfer in 4D‐STEM via Fusion of Complementary Scattering Channels

Advanced Science, Volume 13, Issue 56, 9 October 2026.
Fused Full‐Field STEM (FF‐STEM) is introduced as a 4D‐STEM imaging modality that combines direct ptychography with tilt‐corrected dark‐field reconstruction in a single acquisition. Fourier‐space fusion using Wiener‐type spectral weighting closes the low‐frequency contrast gap inherent to bright‐field methods, delivering gap‐free, dose‐efficient, near ...
Shengbo You, Georgios Varnavides, Sagar Khavnekar, Nikita Palatkin, Sihan Shao, Mingjian Wu, Daniel Stroppa, Darya Chernikova, Baixu Zhu, Ricardo Egoavil, Stefano Vespucci, Dileep Krishnan, Xingchen Ye, Florian K. M. Schur, Erdmann Spiecker, Philipp Pelz   +15 more
wiley   +1 more source

Edge‐Based Discretizations on Triangulations in Any Dimension, With Special Attention to Four‐Dimensional Space

International Journal for Numerical Methods in Fluids, Volume 98, Issue 10, Page 1143-1164, October 2026.
This article provides important geometric formulas for node‐centered, edge‐based schemes in any number of dimensions. These formulas are noteworthy, as they do not require the explicit formation of dual regions. We prove several key geometric results, with a particular focus on the four‐dimensional case, due to potential space‐time applications ...
Nicholas Tufillaro, David M. Williams, Hiroaki Nishikawa   +2 more
wiley   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Organic and Inorganic Pollutants, Oxidative Stress Biomarkers, and Electrophoretic Protein Profiles in an Endangered Thresher Shark (Alopias vulpinus) From Southeastern Brazil: A Case Study

Environmental Toxicology, Volume 41, Issue 10, Page 833-848, October 2026.
ABSTRACT A comprehensive screening of different environmental contaminants (total metals, thermostable metal fractions associated with detoxification, and persistent organic pollutants) was conducted in an endangered common thresher shark (Alopias vulpinus ) individual incidentally captured in southeastern Brazil.
Sidney Fernandes Sales Junior, Amanda Pontes Lopes, Heloíse Martins de Souza, Regina Fonseca, Enrico Mendes Saggioro, Francielli Monteiro Casanova, Kamila Cezar Gramlich, Tatiana Dillenburg Saint'Pierre, Carlos German Massone, Renato Carreira, Rachel Ann Hauser‐Davis   +10 more
wiley   +1 more source

γδ T cells and the PD-1/PD-L1 axis: a love–hate relationship in the tumor microenvironment

Journal of Translational Medicine
Gamma delta (γδ) T cells demonstrate strong cytotoxicity against diverse cancer cell types in an MHC-independent manner, rendering them promising contenders for cancer therapy.
Jian Liu, Min Wu, Yifan Yang, Zixuan Wang, Shan He, Xun Tian, Hui Wang   +6 more
doaj   +1 more source

A Semi‐Resolved LES‐DEM Framework for Turbulent Bedload Transport From Saltation to Sheet‐Flow Regimes

Water Resources Research, Volume 62, Issue 10, October 2026.
Abstract Bedload transport widely occurs in natural environments and encompasses flow regimes from saltation to sheet‐flow, with markedly different fluid‐particle interaction characteristics. Understanding these mechanisms requires a numerical tool capable of capturing both the turbulence and fluid‐particle interactions, for which challenges exist due ...
Yuxiang Liu, Lu Jing, Zi Wu, Xudong Fu
wiley   +1 more source

Advances in γδ T Cells: Cutaneous Biology and Therapeutic Potential for Skin Neoplasms

The Journal of Dermatology, Volume 53, Issue 10, Page 1415-1428, October 2026.
ABSTRACT γδ T cells represent an increasingly important subset of T lymphocytes in the immune response to cancer and as a platform for novel immunotherapies. The aim of this review is to synthesize recent insights into the biology and advances in therapeutic applications of γδ T cells in cutaneous malignancies, especially melanoma, within a framework ...
Simo Du, Anika Jallorina, Toru Yoshino, Lingyu Bao, Han Bao, Victor Chang, Henry K. Wong, Derek V. Chan, Stephen K. Richardson, Mary F. Lee‐Wong   +9 more
wiley   +1 more source