Results 31 to 40 of about 8,778 (220)

A dual role of inflammation in acetaminophen-induced liver injury

Liver Research, 2023
In many affluent nations, acetaminophen (APAP) overdose is the leading cause of drug-induced acute liver failure. The process of APAP-induced liver injury (AILI) is intimately tied to inflammation, including hepatocyte necrosis-caused initiation of ...
Long Xu, Hua Wang
doaj   +1 more source

The parasitic helminth product ES-62 suppresses pathogenesis in collagen-induced arthritis by targeting the interleukin-17–producing cellular network at multiple sites [PDF]

, 2012
Among many survival strategies, parasitic worms secrete molecules to modulate host immune responses. One such product, ES-62, is protective in the collagen-induced arthritis (CIA) model of rheumatoid arthritis.
Al-Riyami, Benderdour, Chu, Collins, Conti, Cooke, Fang, Feng, Goodridge, Goodridge, Goodridge, Gulen, Harnett, Harrington, Ito, Ivanov, Kelchtermans, Kenny, Koenders, Koshy, Kulkarni, Langrish, Lubberts, Marshall, Martin, McInnes, Murugaiyan, Nakae, Naor, Niedbala, Petermann, Pickens, Price, Reynolds, Roark, Sato, Shahrara, Shibata, Staschke, Sutton, Szanto, Takayanagi, Tanaka, Vermeire, Whelan, Xu, Xu, Yago   +47 more
core   +1 more source

Gamma-delta T cells in glioblastoma immunotherapy

Glioma, 2019
Conventional immunotherapy in the treatment of glioblastoma (GBM) has essentially produced no significant advantage over the use of chemotherapeutic drugs.
Sadhak Sengupta
doaj   +1 more source

Gammadelta T cell modulation in anticancer treatment.

Current cancer drug targets, 2010
The broad antimicrobial and antitumoral reactivity of Vgamma9Vdelta2 T cells, their ability to produce inflammatory cytokines involved in protective immunity against intracellular pathogens and tumors and their strong cytolytic and bactericidal activities suggest their direct involvement in immune control of cancers and infections.
CACCAMO, Nadia Rosalia, DIELI, Francesco, MERAVIGLIA, Serena, GUGGINO, Giuliana, SALERNO, Alfredo   +4 more
openaire   +3 more sources

Primary cutaneous aggressive epidermotropic cytotoxic T-cell lymphomas: reappraisal of a provisional entity in the 2016 WHO classification of cutaneous lymphomas. [PDF]

, 2017
Primary cutaneous CD8-positive aggressive epidermotropic T-cell lymphoma is a rare and poorly characterized variant of cutaneous lymphoma still considered a provisional entity in the latest 2016 World Health Organization Classification of Cutaneous ...
Duvic, Madeleine, Girardi, Michael, Guitart, Joan, Ivan, Doina S, Junkins-Hopkins, Jacqueline, Kim, Ellen, Kim, Jinah, Kim, Youn H, Martinez-Escala, M Estela, Olsen, Elise A, Pincus, Laura B, Pulitzer, Melissa P, Rook, Alain H, Sable, Kimberly A, Samimi, Sara S, Selim, M Angelica, Subtil, Antonio, Tetzlaff, Michael T, Virmani, Pooja, Wood, Gary S   +19 more
core   +1 more source

Dual Face of Vγ9Vδ2-T Cells in Tumor Immunology: Anti- versus Pro-Tumoral Activities [PDF]

, 2017
published_or_final_versio
Altincicek, Angelini, Bansal, Baychelier, Beetz, Bennouna, Bonneville, Bonneville, Bouet-Toussaint, Brandes, Brandes, Braza, Caccamo, Caccamo, Caccamo, Capietto, Carlsson, Casetti, Castro, Champsaur, Chen, Chen, Chien, Chien, Cipriani, Cipriani, Conti, Cordova, Correia, Correia, Corvaisier, Dai, Das, Deknuydt, Deniger, Deniger, Devilder, Dharnidharka, Dieli, Dokouhaki, Du, Dudley, Dunne, Dunne, Ferrarini, Ferreira, Fisher, Fournie, Fowler, Fowler, Franchini, Futagbi, Garcia, Gasser, Gertner-Dardenne, Gertner-Dardenne, Girlanda, Glatzel, Gober, Gogoi, Gomes, Groh, Hannani, Harly, Hassan, Hayashi, Hiasa, Hintz, Hoelzinger, Hovav, Hu, Ismaili, Iwasaki, Kalyan, Kang, Kato, Kato, Khan, Kobayashi, Kobayashi, Kobayashi, Kondo, Kong, Kozbor, Kryczek, Kuhl, Lafont, Lafont, Lanca, Lang, Lesport, Li, Li, Lo Presti, Lu, Lv, Maniar, Mao, Meraviglia, Moens, Mookerjee-Basu, Morita, Morita, Muranski, Murugaiyan, Nedellec, Ness-Schwickerath, Ness-Schwickerath, Ngiow, O’Brien, Peters, Peters, Poggi, Qi, Qin, Qin, Qiu, Quezada, Rei, Ribeiro, Ribot, Ribot, Rincon-Orozco, Rischer, Rust, Sandstrom, Schneiders, Sciammas, Scotet, Shao, Shojaei, Sicard, Starick, Sugie, Sutton, Thedrez, Thedrez, Thomas, Todaro, Tokuyama, Toutirais, Tsuda, Tu, Tyler, Vantourout, Vegran, Vermijlen, von Lilienfeld-Toal, Wang, Wesch, Wesch, Wiemer, Wilhelm, Woo, Wright, Wrobel, Wu, Wu, Xiang, Zheng, Zhou   +160 more
core   +5 more sources

A quantitative deficiency in peripheral blood Vγ9Vδ2 cells is a negative prognostic biomarker in ovarian cancer patients. [PDF]

, 2013
International audienceVγ9Vδ2 cells are cytotoxic T cells that are able to recognize epithelial ovarian carcinoma (EOC) cells. Therefore, Vγ9Vδ2 cell-based adoptive transfer is an attractive therapy for EOC.
Cabillic, Florian, Catros, Véronique, Daniel, Pascale, Dessarthe, Benoit, Henno, Sébastien, Jaffre, Isabelle, Lavoué, Vincent, Levêque, Jean, Thedrez, Aurélie   +8 more
core   +12 more sources

Correlation of memory T cell responses against TRAP with protection from clinical malaria, and CD4 CD25 high T cells with susceptibility in Kenyans.

PLoS ONE, 2008
BackgroundImmunity to malaria develops naturally in endemic regions, but the protective immune mechanisms are poorly understood. Many vaccination strategies aim to induce T cells against diverse pre-erythrocytic antigens, but correlates of protection in ...
Stephen M Todryk, Philip Bejon, Tabitha Mwangi, Magdalena Plebanski, Britta Urban, Kevin Marsh, Adrian V S Hill, Katie L Flanagan   +7 more
doaj   +1 more source

RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry. [PDF]

, 2012
The NKG2D stimulatory receptor expressed by natural killer cells and T cell subsets recognizes cell surface ligands that are induced on transformed and infected cells and facilitate immune rejection of tumor cells.
Hsiung, Benjamin, Jung, Heiyoun, Pestal, Kathleen, Procyk, Emily, RAULET, David H.   +4 more
core   +2 more sources

Vδ2+ T cell response to malaria correlates with protection from infection but is attenuated with repeated exposure. [PDF]

, 2017
Vδ2+ γδ T cells are semi-innate T cells that expand markedly following P. falciparum (Pf) infection in naïve adults, but are lost and become dysfunctional among children repeatedly exposed to malaria.
Bowen, Katherine, Boyle, Michelle J, Budker, Rachel, Dorsey, Grant, Farrington, Lila A, Feeney, Margaret E, Greenhouse, Bryan, Jagannathan, Prasanna, Kamya, Moses R, Katureebe, Agaba, Lutwama, Fredrick, McIntyre, Tara I, Musinguzi, Kenneth, Nalubega, Mayimuna, Naluwu, Kate, Nankya, Felistas, Rek, John, Sikyomu, Esther   +17 more
core   +2 more sources