Results 71 to 80 of about 8,778 (220)

Cell-mediated immune response to porcine reproductive and respiratory syndrome virus [PDF]

, 2006
The cell-mediated immune (CMI) response of pigs to porcine reproductive and respiratory syndrome virus (PRRSV) is low in magnitude and appears late after infection. The ability of PRRSV to suppress CMI response is not known.
Charerntantanakul, Wasin
core   +3 more sources

B Cells Regulate Neutrophilia during Mycobacterium tuberculosis Infection and BCG Vaccination by Modulating the Interleukin-17 Response [PDF]

, 2013
We have previously demonstrated that B cells can shape the immune response to Mycobacterium tuberculosis, including the level of neutrophil infiltration and granulomatous inflammation at the site of infection. The present study examined the mechanisms by
A Casadevall, A Cruz, A Glatman-Freedman, AM Cooper, AR Martineau, B Nandi, C Diveu, C Keller, CE Sutton, CG Feng, Christopher M. Sassetti, CJ Thalhofer, CY Hu, D Kitamura, DB Rawool, DJ Cua, DV Jovanovic, E Lockhart, E Marino, E Roy, E Torrado, EB Eruslanov, FE Lund, FL Ribeiro-Gomes, J Hinchey, J Pedrosa, Jiayong Xu, JL Flynn, JM Daley, Joanne L. Flynn, John Chan, JS Thorson, JU Igietseme, K Dunussi-Joannopoulos, K Hamel, KA Sweeney, Kyri Dunussi-Joannopoulos, L Desvignes, L Li, Lee Kozakiewicz, LJ Brady, M Cella, M Laan, M Zhang, MC Tsai, ML Michel, NK Damle, P Miossec, P Seiler, P Ye, PJ Maglione, PJ Maglione, PJ Maglione, PR Hamann, PS Redford, Qinglin Ou, R Appelberg, R Blomgran, R Gopal, RJ North, SA Fulton, SA Khader, ST Passos, Steven A. Porcelli, T Eddens, T Hamilton, T Korn, T Matsushita, TK Kondratieva, W Ouyang, William R. Jacobs, X Zhang, Y Ito, Yanhua Wang, Yong Chen   +74 more
core   +8 more sources

Gamma/delta T cells as cellular vehicles for anti-tumor immunity

Frontiers in Immunology
Adoptive cellular immunotherapy as a new paradigm to treat cancers is exemplified by the FDA approval of six chimeric antigen receptor-T cell therapies targeting hematological malignancies in recent years.
Chelsia Qiuxia Wang, Pei Yu Lim, Andy Hee-Meng Tan, Andy Hee-Meng Tan   +3 more
doaj   +1 more source

Efficacy of Axicabtagene Ciloleucel Compared to Historical Treatments for Relapsed/Refractory Diffuse Large B‐Cell Lymphoma of Asian Descent: A Matching Adjusted Indirect Comparison of ZUMA‐1 vs REAL‐TREND

Hematological Oncology, Volume 43, Issue 3, May 2025.
ABSTRACT To better understand the comparative effectiveness of axicabtagene ciloleucel (axi‐cel) to historical standard of care (SoC) for the treatment of refractory diffused large B‐cell lymphoma (DLBCL) among patients of Asian descent, we conducted a matching‐adjusted indirect treatment comparison (MAIC) of the pivotal ZUMA‐1 trial (NCT02348216) and ...
Frederick L. Locke, Graeme Ball, Markqayne D. Ray, Tony Li, Eve H. Limbrick‐Oldfield, Evan Popoff, Steve Kanters   +6 more
wiley   +1 more source

γδ T LYMPHOCYTES AS A FIRST LINE OF IMMUNE DEFENSE: OLD AND NEW WAYS OF ANTIGEN RECOGNITION AND IMPLICATIONS FOR CANCER IMMUNOTHERAPY.

Frontiers in Immunology, 2014
Among γδT cells, the Vδ1 subset, resident in epithelial tissues, is implied in the defense against viruses, fungi and certain hematological malignancies, while the circulating Vδ2 subpopulation mainly respond to mycobacteria and solid tumors.
Maria Raffaella eZocchi, Alessandro ePoggi   +1 more
doaj   +1 more source

Function and Spatial Organization of Tumor‐Invasive Human γδ T Cells—What Do We Know?

European Journal of Immunology, Volume 55, Issue 1, January 2025.
This review provides deeper insights into the localization of intra‐tumoral γδ T lymphocytes in solid tumors. Additionally, a pro‐ or anti‐tumoral influence of the tumor microenvironment and expression of checkpoint inhibitory molecules on γδ T cell functionality is described.
Kilian Wistuba‐Hamprecht, Hans‐Heinrich Oberg, Daniela Wesch   +2 more
wiley   +1 more source

UEG Week 2022 Poster Presentations

, 2022
United European Gastroenterology Journal, Volume 10, Issue S8, Page 473-1092, October 2022.
wiley   +1 more source

Percentage of {Gamma}{Delta} T Cells in Panniculitis by Paraffin Immunohistochemical Analysis. [PDF]

, 2009
Cutaneous T-cell lymphomas with panniculitis-like histologic features have different clinical courses depending on whether they are composed of alphabeta T cells or gammadelta T cells, necessitating their distinction for proper prognostication.
Choi, John K, Gheith, Shereen M F, MD, PhD, Junkins-Hopkins, Jacqueline M, Mauger, Joanne, Roullet, Michele R   +4 more
core   +1 more source

Evidence That γδ versus αβ T Cell Fate Determination Is Initiated Independently of T Cell Receptor Signaling [PDF]

, 2001
Two types of T cells, alphabeta and gammadelta, develop in vertebrates. How these two T cell lineages arise from a common thymic T progenitor is poorly understood. Differentiation of alphabeta lineage T cells requires the surrogate alpha chain (pTalpha),
Joonsoo Kang, Ariane Volkmann, David H. Raulet, Fehling, Dudley, Penit, Kang, Allison, Kang, Winoto, Livak, MacDonald, Bruno, Wilson, Terrence, Godfrey, Godfrey, Capone, Livák, Wu, Kang, Karasuyama, Volkmann, Hikida, Peschon, Akashi, Maraskovsky, He, Maki, Maki, Perumal, Sudo, Dudley, Kang, Livak, Schlissel, Kranz, Garman, Ishida, Wilson   +39 more
core   +2 more sources

SOX‐5 Transcription Factor: a Novel Psoriatic Autoantigen Preferentially Found in Women

ACR Open Rheumatology, Volume 6, Issue 12, Page 807-819, December 2024.
Objective Adaptive immunity mediates psoriatic disease pathogenesis. We aimed to identify novel psoriatic autoantigens and their phenotypic associations in deeply characterized patient cohorts. Methods Sera from psoriatic arthritis (PsA) patients were used for autoantibody discovery.
Ana‐Maria Orbai, David Fiorentino, Jamie Perin, Erika Darrah, Qingyuan Yang, Laura Gutierrez‐Alamillo, Clifton O. Bingham, Michelle Petri, Antony Rosen, Livia Casciola‐Rosen   +9 more
wiley   +1 more source