Results 1 to 10 of about 10,202 (98)
On the Isolation of Gangliosides. [PDF]
Acta Chemica Scandinavica, 1956 Lars Svennerholm +4 more
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Gangliosides and Neuroblastomas [PDF]
International Journal of Molecular Sciences, 2020 The focus of this review is the ganglio-series of glycosphingolipids found in neuroblastoma (NB) and the myriad of unanswered questions associated with their possible role(s) in this cancer. NB is one of the more common solid malignancies of children. Five-year survival for those diagnosed with low risk NB is 90–95%, while that for children with high ...
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Gangliosides of Human Melanoma2 [PDF]
JNCI: Journal of the National Cancer Institute, 1987 Human melanoma synthesizes a large quantity of gangliosides, glycosphingolipids containing sialic acid. The authors previously have demonstrated that the ganglioside profile differs among individual melanomas and is widely heterogeneous. In the current study, a retrospective study was performed to compare the relationship between the quantity of five ...
Romaine E. Saxton +3 more
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Ganglioside Biochemistry [PDF]
ISRN Biochemistry, 2012 Gangliosides are sialic acid-containing glycosphingolipids. They occur especially on the cellular surfaces of neuronal cells, where they form a complex pattern, but are also found in many other cell types. The paper provides a general overview on their structures, occurrence, and metabolism. Key functional, biochemical, and pathobiochemical aspects are
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Journal of Lipid Research, 1964 The results of recent studies on the complexities of gangliosides from brain, spleen, and erythrocyte stroma are described, and ganglioside nomenclature is discussed. A description of the chemistry and methods of estimation of component groups (sialic acids, hexosamine and hexoses, fatty acids, and sphingosine bases) is followed by an account of the ...
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The biosynthesis of brain gangliosides. Separation of membranes with different ratios of ganglioside sialylating activity to gangliosides [PDF]
Biochemical Journal, 1977 Brain subcellular fractions were analysed for ganglioside-sialylating activity by measuring the incorporation of N-[3H]acetylneuraminic acid from CMP-N-[3H]acetylneuraminic acid into endogenous ganglioside acceptors (endogenous incorporation) and into exogenous lactosyceramide (haematoside synthetase activity). The ratios of endogenous incorporation to
Ranwel Caputto +3 more
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Vascular Diseases and Gangliosides [PDF]
International Journal of Molecular Sciences, 2019 Vascular diseases, such as myocardial infarction and cerebral infarction, are most commonly caused by atherosclerosis, one of the leading causes of death worldwide. Risk factors for atherosclerosis include lifestyle and aging. It has been reported that lifespan could be extended in mice by targeting senescent cells, which led to the suppression of ...
Norihiko Sasaki, Masashi Toyoda
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Mljekarstvo, 2016 Gangliosides belong to a group of glycosphingolipids which are naturally found in biological tissues and fluids including mammalian milks. Considering milk, gangliosides are exclusively found in the membrane of the milk fat globule. Recently, gangliosides are becoming more and more interesting due to their numerous functions.
Marko Mesarić, Slavica Potočki
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The Role of Gangliosides in Neurodevelopment [PDF]
Nutrients, 2015 Gangliosides are important components of neuronal cell membranes and it is widely accepted that they play a critical role in neuronal and brain development. They are functionally involved in neurotransmission and are thought to support the formation and stabilization of functional synapses and neural circuits required as the structural basis of memory ...
Kate Palmano +4 more
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Lipid components of gangliosides
Journal of Lipid Research, 1964 The fatty acids and the long-chain bases of gangliosides from several sources were analyzed by means of gas-liquid chromatography. Stearic acid was found to be the major fatty acid component while palmitic and arachidic acids were found in small amounts, confirming previous observations. Hydroxy acids were not found in any significant amounts.
K. Sambasivarao, R.H. McCluer
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