CREB5 hypermethylation involved in the ganglioside GM1 therapy of Parkinson's disease. [PDF]
Wang R +8 more
europepmc +1 more source
Mixed-monolayer glyconanoparticles for the detection of cholera toxin by surface enhanced raman spectroscopy [PDF]
The same interactions that a pathogen uses for establishment in a host can be exploited in its detection. The carbohydrates comprising the intestinal cell surface GM1-ganglioside, are targeted by vibrio cholerae via the lectin, cholera toxin, to initiate
Craig, Derek +3 more
core +1 more source
Anti-GM1 ganglioside antibodies in Parkinson's disease.
To determine whether anti-GM1 antibodies are increased in Parkinson's disease (PD).Serum immunoglobulin M (IgM) and IgG anti-GM1 antibodies were detected by enzyme-linked immunosorbent assay (ELISA) in 147 patients with PD and in 186 age-matched normal control subjects.
ZAPPIA, MARIO +12 more
openaire +5 more sources
Ganglioside GM1 produces stable, short, and cytotoxic Aβ40 protofibrils. [PDF]
Kumar M, I Ivanova M, Ramamoorthy A.
europepmc +1 more source
Detachment of Membrane Bound Virions by Competitive Ligand Binding Induced Receptor Depletion [PDF]
Multivalent receptor-mediated interactions between virions and a lipid membrane can be weakened using competitive nonpathogenic ligand binding. In particular, the subsequent binding of such ligands can induce detachment of bound virions, a phenomenon of ...
Block, Stephan +4 more
core +1 more source
Corrigendum: CREB5 hypermethylation involved in the ganglioside GM1 therapy of Parkinson's disease. [PDF]
Wang R +8 more
europepmc +1 more source
Structural and functional glycosphingolipidomics by glycoblotting with aminooxy-functionalized gold nanoparticle [PDF]
Glycosphingolipids (GSLs) synthesized in Golgi apparatus by sequential transfer of sugar residues to a ceramide lipid anchor are ubiquitously distributing on vertebrate plasma membranes.
Midori Abe +2 more
core +1 more source
GM1 ganglioside-independent intoxication by Cholera toxin
Cholera toxin (CT) enters and intoxicates host cells after binding cell surface receptors via its B subunit (CTB). We have recently shown that in addition to the previously described binding partner ganglioside GM1, CTB binds to fucosylated proteins. Using flow cytometric analysis of primary human jejunal epithelial cells and granulocytes, we now show ...
Jakob Cervin +18 more
openaire +4 more sources
GM1 ganglioside enzyme-linked immunosorbent assay for detection of heat-labile enterotoxin produced by human and porcine Escherichia coli strains [PDF]
Björn Gustafsson, R. Möllby
openalex +1 more source
Naïve Huntington's disease microglia mount a normal response to inflammatory stimuli but display a partially impaired development of innate immune tolerance that can be counteracted by ganglioside GM1. [PDF]
Steinberg N +4 more
europepmc +1 more source

