Ganoderic acid T improves the radiosensitivity of HeLa cells via converting apoptosis to necroptosis. [PDF]
Shao CS +6 more
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Ganoderic acid a derivative induces apoptosis of cervical cancer cells by inhibiting JNK pathway. [PDF]
Wang M +7 more
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Nano lipidic carriers for codelivery of sorafenib and ganoderic acid for enhanced synergistic antitumor efficacy against hepatocellular carcinoma. [PDF]
Wang B +15 more
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Phosphatidic acid directly activates mTOR and then regulates SREBP to promote ganoderic acid biosynthesis under heat stress in Ganoderma lingzhi. [PDF]
Liu YN +6 more
europepmc +1 more source
Ganoderic Acid A Attenuates LPS-Induced Neuroinflammation in BV2 Microglia by Activating Farnesoid X Receptor. [PDF]
Jia Y +5 more
europepmc +1 more source
Dual inhibitory potential of ganoderic acid A on GLUT1/3: computational and in vitro insights into targeting glucose metabolism in human lung cancer. [PDF]
Bashir MA +7 more
europepmc +1 more source
In vitro inhibitory effects of ganoderic acid A on human liver cytochrome P450 enzymes. [PDF]
Xu S +5 more
europepmc +1 more source
Ganoderic acid A attenuated hepatic impairment by down-regulating the intracellular JAK2-STAT3 signaling pathway in induced mushroom poisoning. [PDF]
Xiao C, Huang G, Cao X, Li X.
europepmc +1 more source
Corrigendum to: Ganoderic acid D prevents oxidative stress-induced senescence by targeting 14-3-3ε to activate CaM/CaMKII/NRF2 signaling pathway in mesenchymal stem cells. [PDF]
europepmc +1 more source
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Ganoderic acid DM: Anti-androgenic osteoclastogenesis inhibitor
Bioorganic and Medicinal Chemistry Letters, 2009Prostate cancer is the most common cancer in men in Western countries, with a high incidence of bone metastasis. Ganoderic acid DM, with 5alpha-reductase inhibitory and androgen receptor (AR) binding activity, isolated from the ethanol extracts of Ganoderma lucidum, can inhibit prostate cancer cell growth and block osteoclastogenesis.
Kuniyoshi Shimizu +2 more
exaly +3 more sources

