Results 81 to 90 of about 5,135,710 (246)

Establishment of the fingerprint of ganoderma lucidum spore powder and study on the anti-inflammatory activity of ganoderma lucidum spore oil

open access: yesGuoji laonian yixue zazhi
[Objective] Establishment of a fingerprinting assay for Ganoderma lucidum spore powder and investigation of the effects of Ganoderma lucidum spore oil on the inflammatory factors IL-1β, IL-6, and TNF-α.
Yu Zhang   +6 more
doaj   +1 more source

Sustainable Natural Product Glycosylation: A Critical Evaluation of Biocatalytic and Chemical Approaches

open access: yesChemSusChem, Volume 18, Issue 20, October 23, 2025.
Developing a process to produce glycosylated natural products involves many decisions, and given the current climate crisis, the environmental impact of the various processes must be a major consideration. This review provides an overview of the various processes and a framework for which metrics should be quantified to select processes that are both ...
Felipe Mejia‐Otalvaro   +3 more
wiley   +1 more source

Farnesoid X Receptor as a potential protein target for mushroom LMW compounds: virtual screening using molecular docking [PDF]

open access: yes, 2017
Farnesoid X receptor (FXR) is a nuclear receptor protein involved in controlling several metabolic pathways, with bile acids as his natural ligands. FXR functions as a sensor for bile acids, thus promoting their clearance by controlling expression of ...
Abreu, Rui M.V., Ferreira, Isabel C.F.R.
core  

Functional Foods Enriched With Bioactive Compounds: Therapeutic Potential and Technological Innovations

open access: yesFood Science &Nutrition, Volume 13, Issue 10, October 2025.
Functional foods enriched with bioactive compounds such as polyphenols, carotenoids, omega‐3 fatty acids, and probiotics provide therapeutic benefits through antioxidant, anti‐inflammatory, and gut‐modulating mechanisms. Advances in biotechnology and AI have improved screening, formulation, and delivery of these compounds in diverse food matrices ...
Zargull Arshad   +4 more
wiley   +1 more source

Influence of cultivation substrate on antioxidant activities and triterpenoid profiles of the fruiting body of Ganoderma lucidum

open access: yesFrontiers in Nutrition
IntroductionThe fruiting body of Ganoderma lucidum has been believed to possess a wide range of therapeutic effects. There are two main methods for artificial cultivation of G.
Gelian Luo   +4 more
doaj   +1 more source

Department of Metabolic Engineering [PDF]

open access: yes, 2002
薬物代謝工学部門は和漢薬の薬効,毒性発現に関与する代謝系の分子生物学的研究を発展させることを設置目的とし,①和漢薬の薬効発現に関与する腸内細菌遺伝子の解析,②薬物代謝機能調節遺伝子の解明とその応用,③腎毒性物質産生機構の分子生物学的解明とその制御に関する研究を課題として取りあげ,和漢薬の薬効発現機構,生体へのレスポンスなどの基礎的研究を通じて,和漢薬の科学的評価や臨床応用をはかることを目指している。主な研究題目を以下に示す。1.
中村 憲夫   +3 more
core   +2 more sources

Single‐cell sequencing and mass spectrometry imaging reveal the multicellular compartmentalization map of plant triterpenes: A ginsenoside in Panax ginseng example

open access: yesPlant Biotechnology Journal, Volume 23, Issue 10, Page 4461-4476, October 2025.
Summary Revealing the multicellular compartmentalization map is crucial for plant breeding and metabolism regulation. Despite the importance of triterpenes as active compounds, there has been no report on their biosynthetic multicellular mapping. In this study, ginsenosides are used as an example to reveal the multicellular compartmentalization map of ...
Rubing Wang   +8 more
wiley   +1 more source

Ubiquitination in cancer: mechanisms and therapeutic opportunities

open access: yesCancer Communications, Volume 45, Issue 9, Page 1128-1161, September 2025.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu   +7 more
wiley   +1 more source

Ganoderic acid and its derivatives as cholesterol synthesis inhibitors.

open access: yesChemical and Pharmaceutical Bulletin, 1989
Oxygenated lanosterol derivatives, which were isolated from Ganoderma lucidum (Polyporaceae) or their derivatives obtained by chemical conversion, were tested for their effect on cholesterol biosynthesis from 24,25-dihydrolanosterol by rat hepatic subcellular 10,000 x g supernatant fraction.
Y, Komoda   +3 more
openaire   +3 more sources

EFEK HEPATOPROTEKTIF EKSTRAK AIR JAMUR LINGZHI (Ganoderma lucidum) PADA TIKUS JANTAN YANG DIINDUKSI PARASETAMOL [PDF]

open access: yes, 2010
INTISARI Hati merupakan pusat metabolisme yang sangat komplek dan penting, dan hati sangat mudah mengalami kerusakan, yang dapat diakibatkan oleh toksisitas obat-obatan. Perbaikan untuk kerusakan hati ini diperlukan senyawa yang bersifat hepatoprotektor,
RAHMAWATI , NUR SEKTI HIDAYAT
core  

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