Results 81 to 90 of about 701,063 (234)
Farnesoid X Receptor as a potential protein target for mushroom LMW compounds: virtual screening using molecular docking [PDF]
, 2017 Farnesoid X receptor (FXR) is a nuclear receptor protein involved in controlling several metabolic pathways, with bile acids as his natural ligands. FXR functions as a sensor for bile acids, thus promoting their clearance by controlling expression of ...
Abreu, Rui M.V., Ferreira, Isabel C.F.R.
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Department of Metabolic Engineering [PDF]
, 2002 薬物代謝工学部門は和漢薬の薬効，毒性発現に関与する代謝系の分子生物学的研究を発展させることを設置目的とし，①和漢薬の薬効発現に関与する腸内細菌遺伝子の解析，②薬物代謝機能調節遺伝子の解明とその応用，③腎毒性物質産生機構の分子生物学的解明とその制御に関する研究を課題として取りあげ，和漢薬の薬効発現機構，生体へのレスポンスなどの基礎的研究を通じて，和漢薬の科学的評価や臨床応用をはかることを目指している。主な研究題目を以下に示す。1.
中村 憲夫 +3 more
core +2 more sources
Plant Biotechnology Journal, Volume 23, Issue 10, Page 4461-4476, October 2025.Summary Revealing the multicellular compartmentalization map is crucial for plant breeding and metabolism regulation. Despite the importance of triterpenes as active compounds, there has been no report on their biosynthetic multicellular mapping. In this study, ginsenosides are used as an example to reveal the multicellular compartmentalization map of ...
Rubing Wang +8 more
wiley +1 more source
Frontiers in NutritionIntroductionThe fruiting body of Ganoderma lucidum has been believed to possess a wide range of therapeutic effects. There are two main methods for artificial cultivation of G.
Gelian Luo +4 more
doaj +1 more source
Antiangiogenic compounds: well-established drugs versus emerging natural molecules [PDF]
, 2018 Angiogenesis is the natural and physiologic process of growing blood vessels from pre-existing ones. Pathological angiogenesis occurs when the precise balance of all the molecular pathways that regulate angiogenesis is disrupted, and this process is a ...
Abreu, Rui M.V. +4 more
core +1 more source
Advances in Clinical and Experimental Medicine, 2021 BACKGROUND Atherosclerosis (AS), a chronic inflammatory disease, is a major contributor to deaths worldwide. Ganoderic acid A (GAA) has been widely applied for various diseases due to its excellent anti-inflammatory properties.
Tao Wang, Huihe Lu
semanticscholar +1 more source
Ubiquitination in cancer: mechanisms and therapeutic opportunities
Cancer Communications, Volume 45, Issue 9, Page 1128-1161, September 2025.Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu +7 more
wiley +1 more source
EFEK HEPATOPROTEKTIF EKSTRAK AIR JAMUR LINGZHI (Ganoderma lucidum) PADA TIKUS JANTAN YANG DIINDUKSI PARASETAMOL [PDF]
, 2010 INTISARI Hati merupakan pusat metabolisme yang sangat komplek dan penting, dan hati sangat mudah mengalami kerusakan, yang dapat diakibatkan oleh toksisitas obat-obatan. Perbaikan untuk kerusakan hati ini diperlukan senyawa yang bersifat hepatoprotektor,
RAHMAWATI , NUR SEKTI HIDAYAT
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Ferroptosis in Cancer and Inflammatory Diseases: Mechanisms and Therapeutic Implications
MedComm, Volume 6, Issue 9, September 2025.Ferroptosis, a form of cell death driven by iron and lipid peroxidation, serves as a bridge between cancer and inflammatory diseases. Microenvironmental factors such as oxidative stress collectively regulate this process. In cancer, ferroptosis exhibits dual roles: while it eliminates drug‐resistant cells, it may also promote tumor metastasis.
Guangyi Shen +4 more
wiley +1 more source
Optimum Condition of Ecologic Feed Fermentation by Pleurotus ostreatus Using Soybean Curd Residue as Raw Materials [PDF]
, 2011 A novel approach by utilizing soybean curd residue, to produce polysaccharide from the edible mushroom Pleurotus ostreatus in solid-state culture, was developed. Firstly, the significant effect of fermented conditions on P.
Li Yiting +7 more
core +1 more source