Results 191 to 200 of about 217,542 (316)

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Calcium-activated adenosine triphosphatase and gap junctions in rat epidermis.

, 1988
Setsuko Kondo, Sadao Imamura, Kazushi Fujimoto, Kazuo Ogawa   +3 more
openalex   +2 more sources

Activity dependent modulation of glial gap junction coupling in the thalamus. [PDF]

iScience
Baum P, Beinhauer A, Zirwes L, Loenneker L, Jabs R, Narayanan RT, Oberlaender M, Seifert G, Kettenmann H, Steinhäuser C.   +9 more
europepmc   +1 more source

Maintenance of hematopoietic stem cell niche homeostasis requires gap junction-mediated calcium signaling. [PDF]

Proc Natl Acad Sci U S A, 2023
Ho KYL, An K, Carr RL, Dvoskin AD, Ou AYJ, Vogl W, Tanentzapf G.   +6 more
europepmc   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Progress report on GaP, grown junction, high temperature diodes

, 1980
R.J. Chaffin
openalex   +2 more sources

Calcium Role in Gap Junction Channel Gating: Direct Electrostatic or Calmodulin-Mediated? [PDF]

Int J Mol Sci
Peracchia C.
europepmc   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Gap junction protein connexin40 is preferentially expressed in vascular endothelium and conductive bundles of rat myocardium and is increased under hypertensive conditions.

, 1993
Bruno Bastide, Ludwig Neyses, Detlev Ganten, M. Paul, Klaus Willecke, Otto Traub   +5 more
openalex   +1 more source

Gap junction messenger RNA expression by vascular wall cells. [PDF]

, 1990
David M. Larson, C C Haudenschild, Eric C. Beyer   +2 more
openalex   +1 more source