Results 201 to 210 of about 217,542 (316)

AAV-mediated base editing restores cochlear gap junction in GJB2 dominant-negative mutation-associated syndromic hearing loss model. [PDF]

JCI Insight
Ukaji T, Arai D, Tsutsumi H, Nakagawa R, Matsumoto F, Ikeda K, Nureki O, Kamiya K.   +7 more
europepmc   +1 more source

When microscopy and electrophysiology meet connectomics-Steve Massey's contribution to unraveling the structure and function of the rod/cone gap junction. [PDF]

Front Ophthalmol (Lausanne), 2023
Ribelayga CP, O'Brien J.
europepmc   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Cloning of a gap junctional protein from vascular smooth muscle and expression in two-cell mouse embryos.

, 1990
J A Lash, E.S. Critser, Milton L. Pressler   +2 more
openalex   +1 more source

Gap junctional channels in adult mammalian sinus nodal cells. Immunolocalization and electrophysiology. [PDF]

, 1992
Justus Anumonwo, H.-Z. Wang, E Trabka-Janik, Brian Dunham, Richard D. Veenstra, Mario Delmar, José Jalife   +6 more
openalex   +1 more source

The rectification of heterotypic Cx46/Cx50 gap junction channels depends on intracellular magnesium. [PDF]

Biophys Rep
Chen H, Bai D.
europepmc   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Gap junction distribution is altered between cardiac myocytes infected with Trypanosoma cruzi. [PDF]

, 1992
Antônio Carlos Campos de Carvalho, Herbert B. Tanowitz, Murray Wittner, Rolf Dermietzel, Christine Le Roy, Elliot L. Hertzberg, David C. Spray   +6 more
openalex   +1 more source

Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe

Molecular Oncology, EarlyView.
Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns, Ulrik Ringborg, Julio Celis, Bengt Jönsson, Michael Baumann   +4 more
wiley   +1 more source

Gap junction-transported cAMP from the niche controls stem cell progeny differentiation. [PDF]

Proc Natl Acad Sci U S A, 2023
Tu R, Tang XA, Xu R, Ping Z, Yu Z, Xie T.   +5 more
europepmc   +1 more source