Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
An Extensive Gap Junction Neural Network Modulates <i>Caenorhabditis elegans</i> Aversive Behavior. [PDF]
Sojka SE +6 more
europepmc +1 more source
Gap Distance and Interactions in a Molecular Tunnel Junction
Shuai Chang +4 more
openalex +2 more sources
Connexin-43-type gap junctions mediate communication between bone marrow stromal cells [PDF]
Kenneth Dorshkind +3 more
openalex +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Gap junction protein beta 5 interacts with Gαi3 to promote Akt activation and cervical cancer cell growth. [PDF]
Li P, Chen J, Wang J, Liu T.
europepmc +1 more source
Gap junctional intercellular communication and cell proliferation during rat liver carcinogenesis.
Hideo Yamasaki +5 more
openalex +2 more sources
Mind the gap: mechanisms regulating the endothelial barrier
M. Radeva, J. Waschke
semanticscholar +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
Developmental Changes in Gap Junction Expression in Rat Adrenal Medullary Chromaffin Cells. [PDF]
Nakashima T +6 more
europepmc +1 more source

