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Integrative analyses identified gap junction beta-2 as a prognostic biomarker and therapeutic target for breast cancer. [PDF]
Cancer InnovZhang D, Li L, Ma F.
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Comprehensive Physiology, 2012
Abstract Gap junctions are essential to the function of multicellular animals, which require a high degree of coordination between cells. In vertebrates, gap junctions comprise connexins and currently 21 connexins are known in humans.
Nielsen, Morten Schak +5 more
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Abstract Gap junctions are essential to the function of multicellular animals, which require a high degree of coordination between cells. In vertebrates, gap junctions comprise connexins and currently 21 connexins are known in humans.
Nielsen, Morten Schak +5 more
+6 more sources
Selective permeability of gap junction channels
Biochimica Et Biophysica Acta - Biomembranes, 2004 Gap junctions mediate the transfer of small cytoplasmic molecules between adjacent cells. A family of gap junction proteins exist that form channels with unique properties, and differ in their ability to mediate the transfer of specific molecules ...
Gary S Goldberg +2 more
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2023
Gap junctions, comprising connexin proteins, create conduits directly coupling the cytoplasms of adjacent cells. Expressed in essentially all tissues, dynamic gap junction structures enable the exchange of small molecules including ions and second messengers, and are central to maintenance of homeostasis and synchronized excitability. With such diverse
Michael J, Zeitz, James W, Smyth
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Gap junctions, comprising connexin proteins, create conduits directly coupling the cytoplasms of adjacent cells. Expressed in essentially all tissues, dynamic gap junction structures enable the exchange of small molecules including ions and second messengers, and are central to maintenance of homeostasis and synchronized excitability. With such diverse
Michael J, Zeitz, James W, Smyth
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Annual Review of Physiology, 1981
The formation of low resistance pathways is one of the most common forms of cellular interaction. Since its discovery between neurons (40) this form of cell-to-cell communication has been documented widely in both excitable and nonexcitable cells.
E L, Hertzberg +2 more
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The formation of low resistance pathways is one of the most common forms of cellular interaction. Since its discovery between neurons (40) this form of cell-to-cell communication has been documented widely in both excitable and nonexcitable cells.
E L, Hertzberg +2 more
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Gap junction- and hemichannel-independent actions of connexins
Biochimica Et Biophysica Acta - Biomembranes, 2005 Connexins have been known to be the protein building blocks of gap junctions and mediate cell–cell communication. In contrast to the conventional dogma, recent evidence suggests that in addition to forming gap junction channels, connexins possess gap ...
Jean X Jiang, Sumin Gu
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Annual Review of Physiology, 1985
Gap junctions [also called nexus (15) or maculae communicantes (102)] repre sent transcellular channels that permit the exchange of small molecules and ions between neighboring cells (28, 33, 74, 75, 82, 86, 89, 103). They differ from other membrane channels in a number of respects: they provide a pathway between cells rather than across one cell ...
Revel, J.-P. +2 more
openaire +3 more sources
Gap junctions [also called nexus (15) or maculae communicantes (102)] repre sent transcellular channels that permit the exchange of small molecules and ions between neighboring cells (28, 33, 74, 75, 82, 86, 89, 103). They differ from other membrane channels in a number of respects: they provide a pathway between cells rather than across one cell ...
Revel, J.-P. +2 more
openaire +3 more sources