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Seminars in Cell Biology, 1992
Gap junction channels, now known to be formed of connexins, connect the interiors of apposed cells. These channels can be opened and closed by various physiological stimuli and experimental treatments. They are permeable to ions and neutral molecules up to a size of about 1 kDa or 1.5 nm diameter, including second messengers and metabolites.
M V, Bennett, V K, Verselis
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Gap junction channels, now known to be formed of connexins, connect the interiors of apposed cells. These channels can be opened and closed by various physiological stimuli and experimental treatments. They are permeable to ions and neutral molecules up to a size of about 1 kDa or 1.5 nm diameter, including second messengers and metabolites.
M V, Bennett, V K, Verselis
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Journal of Cell Science, 1988
ABSTRACT Gap junctions are intercellular structures that link cells and allow them to exchange ions and small metabolites without recourse to the extracellular space (for reviews and early references, see Goodenough, 1979; Loewen-stein, 1981).
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ABSTRACT Gap junctions are intercellular structures that link cells and allow them to exchange ions and small metabolites without recourse to the extracellular space (for reviews and early references, see Goodenough, 1979; Loewen-stein, 1981).
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The electrophysiology of gap junctions and gap junction channels and their mathematical modelling
Biology of the Cell, 2002Summry— In most tissues of vertebrates, gap junctions control the exchange of ions and small molecules between adjacent cells, thus co‐ordinating the cellular activities. The application of the dual voltage‐clamp method to cell pair preparations enables one to elucidate the electrical properties of gap junctions and gap junction channels.
Vogel R, Weingart R
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Journal of Cell Science, 1977
ABSTRACT Both glycerol and glutaraldehyde, the two most commonly used chemical aids in freeze-fracture studies, have been shown individually to affect the structure of certain membranes as observed in freeze-fracture replicas. The present investigation studied the effect of glycerol on the gap junctions found in a number of tissues from ...
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ABSTRACT Both glycerol and glutaraldehyde, the two most commonly used chemical aids in freeze-fracture studies, have been shown individually to affect the structure of certain membranes as observed in freeze-fracture replicas. The present investigation studied the effect of glycerol on the gap junctions found in a number of tissues from ...
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Gap junction proteins form specialized intercellular communication channels, including electrical synapses, that regulate cellular metabolism and signaling. We present a molecular inventory of the gap junction proteins-innexins (INX-like) in ctenophores, focusing on two reference species, Pleurobrachia bachei and Mnemiopsis leidyi.
Andrea B, Kohn, Leonid L, Moroz
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Andrea B, Kohn, Leonid L, Moroz
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Gap Junctions as Electrical Synapses
Journal of Neurocytology, 1996Gap junctions are the morphological substrate of one class of electrical synapse. The history of the debate on electrical vs. chemical transmission is instructive. One lesson is that Occam's razor sometimes cuts too deep; the nervous system does its operations in a number of different ways and a unitarian approach can lead one astray.
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1993
One of the main avenues by which cells communicate with each other is through transmembranous channels which span the extracellular space, thereby allowing the direct transfer of small molecules and ions. The size range of admitted molecules allows the diffusion of current-carrying ions such as K+, Na+, Cl-, and second messenger molecules such as cAMP,
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One of the main avenues by which cells communicate with each other is through transmembranous channels which span the extracellular space, thereby allowing the direct transfer of small molecules and ions. The size range of admitted molecules allows the diffusion of current-carrying ions such as K+, Na+, Cl-, and second messenger molecules such as cAMP,
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Tight Junctions and Gap Junctions
2010Tight junctions have several major functions. They seal the intercellular space in epithelial and endothelial cell layers and prevent free paracellular passage of substances. They determine the polarity of epithelial cells by creating a boundary between the apical domain of the plasma membrane and the basolateral domain and prevent diffusion of lipids ...
Margit Pavelka, Jürgen Roth
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