Results 281 to 290 of about 2,836,933 (367)

Effects of Ionizing Radiation and Reactive Oxygen Species on Gap Junctional Intercellular Communication

, 2000
Toshiyasu Iwasaki, Yuko Hoshi, Takaharu Nomura, Tomonori Hayashi, Ikuno Suzuki, Futaba Amano, Kazuo Sakai   +6 more
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Activity dependent modulation of glial gap junction coupling in the thalamus. [PDF]

iScience
Baum P, Beinhauer A, Zirwes L, Loenneker L, Jabs R, Narayanan RT, Oberlaender M, Seifert G, Kettenmann H, Steinhäuser C.   +9 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

The innexin 7 gap junction protein contributes to synchronized activity in the <i>Drosophila</i> antennal lobe and regulates olfactory function. [PDF]

Front Neural Circuits
Fuenzalida-Uribe N, Hidalgo S, Silva B, Gandhi S, Vo D, Zamani P, Holmes TC, Sayin S, Grunwald Kadow IC, Hadjieconomou D, O'Dowd DK, Campusano JM.   +11 more
europepmc   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

<i>Ex vivo</i> expanded human regulatory T cells promote cholesterol efflux and PON1 expression in oxLDL-exposed macrophages via gap junction-mediated cAMP transfer. [PDF]

Front Immunol
Albany CJ, Mastronicola D, Popov M, Stroukov W, Wierzbicki AS, Martinez-Nunez RT, Lombardi G, Scottà C.   +7 more
europepmc   +1 more source

Characterization of a variant of gap junction protein α8 identified in a family with hereditary cataract

, 2017
Debbie S. Kuo, Jared T. Sokol, Peter J. Minogue, Viviana M. Berthoud, Anne Slavotinek, Eric C. Beyer, Douglas B. Gould   +6 more
openalex   +2 more sources

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Assessment of Gene Expression on the Gap Junction Connexin of Cumulus Cells on Infertile Women With Polycystic Ovary Syndrome and Poor Ovarian Response: The Novel Role of Propranolol. [PDF]

J Family Reprod Health
Zafari Zangeneh F, Naghizadeh MM, Jafarabadi M, Dehghan M, Bagheri M.   +4 more
europepmc   +1 more source