Results 111 to 120 of about 15,677 (174)

N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting [PDF]

, 2015

core   +1 more source

Nuclear gasdermin E drives endothelin-1-induced metastatic progression independently of the pyroptosis. [PDF]

Cell Death Dis
Roman C, Caprara V, Tocci P, Sacconi A, Blandino G, Bagnato A, Sestito R.   +6 more
europepmc   +1 more source

Duck gasdermin E is a substrate of caspase-3/-7 and an executioner of pyroptosis. [PDF]

Front Immunol, 2022
Li H, Wang X, Yu L, Wang J, Cao Y, Ma B, Zhang W.   +6 more
europepmc   +1 more source

Exploring the Post Cleavage Interactions of Gasdermin E

Pyroptosis is a type of programmed cell death activated by lethal stimuli to cleave gasdermins (GSDMs) into N-terminal pore forming and C-terminal autoinhibitory domains. Pyroptosis leads to inflammation which can be harnessed for host defense during infection and to promote anti-tumor immunity.
openaire   +1 more source

Nicotinamide riboside attenuates radiation-induced intestinal injury by suppressing gasdermin E-mediated pyroptosis in intestinal epithelial cells. [PDF]

J Transl Med
Zhou Q, Liu L, Lin X, Shen B, Huang W, Zhang Y, Li Y, Yang Y, Liu H, Zhang W, Zhao X, Qiao W, Liu Y, Tan G, Zhi F.   +14 more
europepmc   +1 more source

A high-throughput Gaussia luciferase reporter assay for screening potential gasdermin E activators against pancreatic cancer. [PDF]

Acta Pharm Sin B, 2023
Liu Y, Zhang X, Zhang P, He T, Zhang W, Ma D, Li P, Chen J.   +7 more
europepmc   +1 more source

Foot-and-Mouth Disease Virus Induces Porcine Gasdermin E-Mediated Pyroptosis through the Protease Activity of 3C^pro. [PDF]

J Virol, 2023
Ren X, Yin M, Zhao Q, Zheng Z, Wang H, Lu Z, Li X, Qian P.   +7 more
europepmc   +1 more source

Gasdermin E regulates the stability and activation of EGFR in human non-small cell lung cancer cells. [PDF]

Cell Commun Signal, 2023
Xu L, Shi F, Wu Y, Yao S, Wang Y, Jiang X, Su L, Liu X.   +7 more
europepmc   +1 more source

Dual function of Gasdermin E: pyroptosis-mediated pan-cancer suppression versus HCC-specific oncogenic activity. [PDF]

Front Immunol
Kahaer G, Pan S, Yang C, Xie W, Lu Y.
europepmc   +1 more source

Gasdermin E mediates pyroptosis in the progression of hepatocellular carcinoma: a double-edged sword. [PDF]

Gastroenterol Rep (Oxf)
Lu Y, Xu J, Lin H, Zhu M, Li M.
europepmc   +1 more source