Results 81 to 90 of about 70,974 (289)

Persistence of anticancer activity in berry extracts after simulated gastrointestinal digestion and colonic fermentation [PDF]

, 2012
Fruit and vegetable consumption is associated at the population level with a protective effect against colorectal cancer. Phenolic compounds, especially abundant in berries, are of interest due to their putative anticancer activity.
Allsopp Philip, Magee Pamela, González-Barrio, Rocio, Rocio González-Barrio (117854), McDougall, Gordon J., Gill, Chris I. R., Philip Allsopp (117857), Ian Rowland (117868), Gordon J. McDougall (117848), Gema Pereira-Caro (117851), Derek Stewart, Gema Pereira-Caro, McDougall Gordon J., Crozier Alan, Magee, Pamela, McDougall, G.J., Pamela Magee (117861), Philip Allsopp, Pamela Magee, Stewart Derek, Gordon J McDougall, Pereira-Caro, Gema, Gill Chris I. R., Stewart, D., Ian Rowland, Brown, E.M., Alan Crozier (117865), Brown Emma M., Gill, C.I.R., Pereira-Caro Gema, Derek Stewart (117849), Stewart, Derek, González-Barrio, R., Rowland, Ian, Pereira Caro, G., Emma M. Brown (117847), Rowland Ian, Rocio González-Barrio, Chris I R Gill, Pereira-Caro, G., Alan Crozier, Magee, P., Allsopp, P., González-Barrio, R, Crozier, A., Rowland, I., González-Barrio Rocio, Allsopp, Philip, Emma M Brown, Chris I. R. Gill (117871), Brown, Emma M., Crozier, Alan   +51 more
core   +1 more source

Genome‐Wide In Vivo RNAi Screening Identifies HOXD4 as a Tumor Metastasis Suppressor in Colorectal Cancer

Advanced Science, EarlyView.
Metastasis remains a major challenge in colorectal cancer. Using an in vivo shRNA screening system, this study identifies Homeobox D4 as a key metastasis suppressor. Reduced Homeobox D4 expression is associated with aggressive tumor features. Functional and mechanistic analyses show that it inhibits epithelial‐mesenchymal transition by repressing ...
Zhi‐hua Ye, Wen‐jing Luo, Lu Li, Wen‐di Shuai, Ling Zhou, You‐fa Duan, Xue Chen, Jun‐kai Zhang, Wenlin Huang, Ran‐yi Liu   +9 more
wiley   +1 more source

Soleil Synchrotron illuminates our knowledge on gastric digestion [PDF]

, 2019
Soleil Synchrotron illuminates our knowledge on gastric digestion ...
Floury, Juliane
core   +3 more sources

Digestive Action of Human Gastric Juice.

Experimental Biology and Medicine, 1956
Summary1. The digestive capacity of human gastric juice, adjusted to pH 1.6-1.7, has been measured by perfusion of the cat's esophagus. 2. The gastric secretions of patients with duodenal ulcer, patients in the early postoperative period, and acutely ill patients showed significantly increased necrotizing effects on the esophagus as compared with ...
J F, PERRY, E G, YONEHIRO, P M, YA, H D, ROOT, O H, WANGENSTEEN   +4 more
openaire   +2 more sources

HNRNPD Induces Radioresistance in Nasopharyngeal Carcinoma by Sequestering GRAMD4 mRNA in Stress Granules

Advanced Science, EarlyView.
HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li, Tong Xiang, Yuanyuan Liu, Desheng Weng, Jingjing Zhao, Hao Chen, Yan Tang, Songzuo Xie, Hao Zhang, Jun Luo, Xinyi Yang, Qiuzhong Pan, Muping Di, Jianchuan Xia   +13 more
wiley   +1 more source

Antioxidant indices and amino acid composition of phenolic containing Lima beans (Phaseolus lunatus) after simulated human gastrointestinal digestion

International Journal of Food Studies, 2019
The present investigation was designed to characterize the phenolic profile of Lima beans (Phaseolus Lunatus) and also to evaluate the antioxidant indices: total phenolic content (TPC), total flavonoid content (TFC), ferric reducing antioxidant power ...
Sule O. Salawu, Oluwaseun M. Folorunso, Akintunde A. Akindahunsi, Aline A. Boligon   +3 more
doaj   +1 more source

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

Small Extracellular Vesicles‐Derived Circ6718 Unlocks Stromal Remodeling and Serves as a Biomarker in Gastric Cancer

Advanced Science, EarlyView.
sEVs‐circ6718 serves as a promising serum biomarker for gastric cancer early diagnosis and prognosis, promoting malignant transformation in gastric cancer cells and GC‑MSC differentiation into CAFs. sEVs‑circ6718 holds potential as a biomarker for the early diagnosis and prognostic assessment of gastric cancer.
Fan Zhang, Xueyan Zang, Dongli Wang, Rong Li, Hui Qian, Wenrong Xu, Jiajia Jiang, Yongmin Yan   +7 more
wiley   +1 more source

Dynamic Changes in Amino Acid Release Patterns of Different Plant Protein Sources During In Vitro Digestion and Their Nutritional Value Assessment

Animals
A gastric–intestinal two-step enzymatic hydrolysis in vitro digestion simulation system was used to systematically investigate the digestion kinetics and amino acid release characteristics of five plant protein sources: soybean meal, rapeseed meal, corn ...
Yueli Fan, Zehua Kou, Jiahua Cao, Zhongshen Wang, Tianrui Zhang, Rui Han, Dongsheng Che   +6 more
doaj   +1 more source

Gastric Digestion of Soybean Flour

Journal of Dairy Science, 1937
Summary A soybean gruel made by mixing one part of soybean flour with nine parts of water was compared with whole and skim milk for calf feeding. A "fortified" soybean gruel in which skim milk solids made up one third of the total solids of the gruel was also tried. The results were analyzed in terms of (1) cubic centimeters of gastric juice collected
La Van Shoptaw, D.L. Espe, C.Y. Cannon
openaire   +1 more source