Results 81 to 90 of about 455,808 (290)
Advanced Science, EarlyView.This study reveals a novel GC therapy targeting cholesterol homeostasis. Inhibiting the SCAP sterol‐sensing domain causes lethal ER stress via cholesterol accumulation, paradoxically forcing continuous synthesis that triggers ferroptosis. The findings link sterol sensing, metabolic dysregulation, and ferroptosis, establishing an anti‐cancer paradigm ...
Qianqian Xu +17 more
wiley +1 more source
FoodsThe global dairy market has been increasingly diversified with more dairy product offerings of milk products from different animal species. Meanwhile, milk powders remain the main exported dairy product format due to their ease of transportation. In this
Siqi Li +9 more
doaj +1 more source
Digestion of Milk from Red Chittagong Cattle Focusing Proteolysis and Lipolysis [PDF]
Asian-Australasian Journal of Animal Sciences, 2015 Ex vivo digestion of proteins and fat in Red Chittagong Cattle milk from Bangladesh was carried out using human gastrointestinal enzymes. This was done to investigate the protein digestion in this bovine breed’s milk with an especial focus on the ...
Mohammad Ashiqul Islam +3 more
doaj +1 more source
Advanced Science, EarlyView.An integrated probiotic system is engineered to execute a programmed therapeutic cascade against inflammatory bowel disease. Upon pathological signals, the system sequentially performs ROS scavenging, tungsten release, and selective pathogen suppression, thereby breaking the oxidative stress–dysbiosis cycle to remodel gut microbiota and reinforce ...
Yang Yang +8 more
wiley +1 more source
Shipin gongye ke-jiThis paper aimed to investigate the antioxidant activity of buckwheat bee pollen polysaccharides (BWPP) during the in vitro gastrointestinal digestion. The crude polysaccharides were purified using DEAE-52 cellulose column and their antioxidant activity ...
Hua WANG +6 more
doaj +1 more source
REGγ Suppresses Ferroptosis and Induces Drug Resistance by Degrading WDR6 in Chondrosarcoma
Advanced Science, EarlyView.Here, we identified REGγ as a susceptibility factor in chondrosarcoma. Our study demonstrates that abnormally activated REGγ‐20S proteasome promotes chondrosarcoma development and progression. Further validation in animal models revealed that blocking REGγ function induced ferroptosis, suppressed malignant progression of chondrosarcoma, and uncovered a
Fanrong Liu +20 more
wiley +1 more source
Advanced Science, EarlyView.A highly sensitive SERS‐based platform measures PD‐L1 expression on EpCAM+ circulating EVs from cancer patients undergoing immunotherapy. Monitoring dynamic changes after treatment reveals that reduced EpCAM+ EV PD‐L1 levels associate with improved long‐term clinical outcomes, establishing a non‐invasive approach for tracking immune checkpoint ...
Byeonggeol Mun +15 more
wiley +1 more source
Anaerobic digestion of catering wastes
, 2008 This research addresses gaps in current knowledge regarding process issues associatedwith long term semi-continuous digestion of food waste as a sole substrate, and the role oftrace elements and biomass retention in digestion of food wastes.Source ...
Climenhaga, Martha Anne
core +1 more source
Digestive Action of Human Gastric Juice.
Experimental Biology and Medicine, 1956 Summary1. The digestive capacity of human gastric juice, adjusted to pH 1.6-1.7, has been measured by perfusion of the cat's esophagus. 2. The gastric secretions of patients with duodenal ulcer, patients in the early postoperative period, and acutely ill patients showed significantly increased necrotizing effects on the esophagus as compared with ...
J F, PERRY +4 more
openaire +2 more sources
, 2012 Many differences in clinicopathological features of gastric cancer and its treatment have been reported between the East and the West however such a comparison using Australian data is still lacking. Gastric cancers seen in Australia differ significantly
Kwon, Sebastianus +11 more
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