Results 71 to 80 of about 375 (127)

Gastrin-releasing peptide and satiety

open access: yesGastroenterology, 1994
James Gibbs   +2 more
openaire   +1 more source
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Gastrin-Releasing Peptide in Hypoplastic Lungs

Pediatric Pathology & Laboratory Medicine: Journal of the Society for Pediatric Pathology, Affiliated With the International Paediatric Pathology Association, 1996
The relative abundance of pulmonary neuroendocrine cells synthesizing gastrin-releasing peptide (GRP) was estimated for normal fetal lungs and hypoplastic lungs. Percentage of bronchiolar epithelial area staining positively with anti-GRP antiserum was computed for each case using a SAMBA 4000 image analyzer.
Patricia Thomas   +2 more
exaly   +3 more sources

Gastrin-releasing peptide and cancer

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2006
Over the past 20 years, abundant evidence has been collected to suggest that gastrin-releasing peptide (GRP) and its receptors play an important role in the development of a variety of cancers. In fact, the detection of GRP and the GRP receptor in small cell lung carcinoma (SCLC), and the demonstration that anti-GRP antibodies inhibited proliferation ...
Oneel, Patel   +2 more
openaire   +2 more sources

Molecular Basis of the Selectivity of Gastrin-Releasing Peptide Receptor for Gastrin-Releasing Peptide

Molecular Pharmacology, 2002
The mammalian bombesin peptides [gastrin-releasing peptide (GRP) and neuromedin B (NMB)] are important in numerous biological and pathological processes. These effects are mediated by the heptahelical GRP receptor (GRPR) and NMB receptor (NMBR). GRP has high affinity for GRPR and lower affinity for NMBR.
Kenji, Tokita   +3 more
openaire   +2 more sources

Insulinotropic and gastrin-releasing action of gastrin-releasing peptide (GRP)

Regulatory Peptides, 1984
The effect of intravenous administration of gastrin-releasing peptide ( GRP ) on serum gastrin and insulin levels was studied in ad libitum fed and 24-h fasted rats. Administration of GRP (55 micrograms/kg body weight) caused a significant (P less than 0.05) elevation in serum gastrin levels at 10, 30, 60, and 120 min in the rats fed ad libitum ...
G H, Greeley, J C, Thompson
openaire   +2 more sources

Gastrin-releasing-peptide in neuroendorine tumours

Acta Oncologica, 2006
In a substantial proportion of cases with endocrine malignant disease the primary lesion cannot be localised and the pathologist hesitates upon the origin of the tumour. Well differentiated neuroendocrine carcinomas of the small bowel can usually be identified by the strong serotonin immunoreactivity, but foregut carcinoids may also stain positive for ...
Dan, Granberg   +5 more
openaire   +2 more sources

Gastrin-Releasing Peptide in the Porcine Pancreas

Gastroenterology, 1987
The presence of gastrin-releasing peptide (GRP) was studied in extracts of porcine pancreata. Gel filtration and high-pressure liquid chromatographic profiles of these extracts as monitored with both C-terminally and N-terminally directed radioimmunoassays against GRP showed pancreatic GRP to consist of one main form, namely the 27-amino acid peptide ...
S, Knuhtsen   +6 more
openaire   +2 more sources

Analysis of gastrin-releasing peptide gene and gastrin-releasing peptide receptor gene in patients with agoraphobia

Psychiatric Genetics, 2014
A gastrin-releasing peptide receptor (GRPR) knock-out mouse model provided evidence that the gastrin-releasing peptide (GRP) and its neural circuitry operate as a negative feedback-loop regulating fear, suggesting a novel candidate mechanism contributing to individual differences in fear-conditioning and associated psychiatric disorders such as ...
Katrin, Zimmermann   +13 more
openaire   +2 more sources

Paradoxical effects of gastrin releasing peptide on gastrin release and gastric secretion in the rat

Gastroenterologia Japonica, 1986
The effects of gastrin releasing peptide (GRP) on gastrin release and gastric secretion were studied in anesthetized rats. Intravenous infusion of GRP (1-16 micrograms/kg/hr) caused a dose-dependent increase in serum gastrin level, however, it had no effect on basal gastric secretion in the lumen-perfused stomach preparation. Furthermore, GRP inhibited
A, Takagi   +4 more
openaire   +2 more sources

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