Results 51 to 60 of about 375 (127)

Emerging agents for boron neutron capture therapy: Biomolecular carriers paving the way for precision radiotherapy

Precision Radiation Oncology, Volume 10, Issue 2, Page 254-264, June 2026.
Boron neutron capture therapy (BNCT) requires key non‐negotiable technical criteria: megadose administration, precise tumor‐specific targeting, favorable biocompatibility, and sustained tumor retention. Overcoming these interconnected challenges fundamentally depends on biomolecular carriers, which are critical for translating the therapeutic potential
Chang Chen, Maosong Yang, Jiheng Wang, Ling Zhang, Shaobo Huang, Xiao Xu, Yang Liu   +6 more
wiley   +1 more source

Neuropeptide Y neurons mediate opioid-induced itch by disinhibiting GRP-GRPR microcircuits in the spinal cord

Nature Communications
Itch is a common side effect of opioid analgesics. The specific neurons mediating opioid-induced itch are still debated, and the mechanistic neuronal circuits remain elusive.
Qian Zeng, Yitong Li, Yifei Wu, Jiawei Wu, Kangtai Xu, Yiming Chen, Yunfei Rao, Nan Li, Yuhui Luo, Changyu Jiang, Chaoran Wu, Zilong Wang   +11 more
doaj   +1 more source

Acute Endobronchial Dissemination of a Tuberculoma Following EBUS‐GS‐Guided Transbronchial Biopsy: A Case Report

Respirology Case Reports, Volume 14, Issue 6, June 2026.
Acute endobronchial dissemination highly suggestive of a procedure‐associated event occurred after EBUS‐GS‐guided biopsy of a pulmonary tuberculoma. Because tuberculoma may mimic lung cancer, clinicians should consider tuberculosis in solitary nodules and monitor carefully for dissemination after bronchoscopy when necrotic lesions are sampled ...
Haruno Tsukagoshi, Yasuto Ueda, Tatsuya Nakada, Takashi Sumikawa, Yasuyuki Hasegawa, Mizuho Matsushita, Hiroki Chikumi, Akira Yamasaki   +7 more
wiley   +1 more source

In vitro gastrin-releasing peptide response in chicken ovarian follicles

Poultry Science
The gastrin-releasing peptide (GRP) is reported to be mainly produced by the pituitary in chickens, with its receptor (GRPR) highly expressed in the ovaries, indicating its regulatory role in ovarian function. Present study aims to verify the role of GRP
Chunheng Mo, Can Lv, Guoqiang Zhu, Jiannan Zhang, Yuanyou Li, Yajun Wang, Juan Li   +6 more
doaj   +1 more source

Critical evaluation of the expression of gastrin-releasing peptide in dorsal root ganglia and spinal cord

Molecular Pain, 2016
There are substantial disagreements about the expression of gastrin-releasing peptide (GRP) in sensory neurons and whether GRP antibody cross-reacts with substance P (SP).
Devin M Barry PhD, Hui Li PhD, Xian-Yu Liu PhD, Kai-Feng Shen PhD, Xue-Ting Liu PhD, Zhen-Yu Wu, Admire Munanairi PhD, Xiao-Jun Chen, Jun Yin, Yan-Gang Sun PhD, Yun-Qing Li PhD, Zhou-Feng Chen PhD   +11 more
doaj   +1 more source

Localization of ^99mTc-GRP Analogs in GRPR-Expressing Tumors: Effects of Peptide Length and Neprilysin Inhibition on Biological Responses

Pharmaceuticals, 2019
The overexpression of gastrin-releasing peptide receptors (GRPRs) in frequently occurring human tumors has provided the opportunity to use bombesin (BBN) analogs as radionuclide carriers to cancer sites for diagnostic and therapeutic purposes.
Aikaterini Kaloudi, Emmanouil Lymperis, Panagiotis Kanellopoulos, Beatrice Waser, Marion de Jong, Eric P. Krenning, Jean Claude Reubi, Berthold A. Nock, Theodosia Maina   +8 more
doaj   +1 more source

Oxygen, Gastrin-Releasing Peptide, and Pediatric Lung Disease: Life in the Balance

Frontiers in Pediatrics, 2014
Excessive oxygen (O2) causes tissue injury, scarring, aging, and even death. Our laboratory is studying O2-sensing pulmonary neuroendocrine cells (PNECs) and the PNEC-derived product gastrin-releasing peptide (GRP).
Mary E Sunday
doaj   +1 more source

The Challenge of Basic Itch Research

Acta Dermato-Venereologica, 2020
Basic mechanisms and pathways of itch signaling are reviewed, with an emphasis on the progress to date as well as remaining challenges in translating current knowledge to the clinical treatment of chronic itch.
Earl Carstens, Taylor Follansbee, Mirela Iodi Carstens   +2 more
doaj   +1 more source

The application of 18F-FDG PET/CT with tumor markers NSE and ProGRP in the diagnosis and treatment of small cell lung cancer [PDF]

精准医学杂志
Small cell lung cancer (SCLC) is the most common neuroendocrine tumor in the lungs. SCLC is characterized by high malignancy and high recurrence and metastasis rates.
LIN Shuai, WANG Yanli
doaj   +1 more source

Gastrin‐Releasing Peptide Facilitates Cholinergically Mediated Contractions of the Mouse Gastric Fundus

Pharmacology Research & Perspectives
Gastrin‐releasing peptide (GRP) and neuromedin B (NMB) are found in the stomach's myenteric plexus and muscular layers. When exogenously administered, they contract stomach muscle in several species, but their ability to modulate enteric nerve functions ...
Diego Currò, Raj Makwana, Gareth J. Sanger   +2 more
doaj   +1 more source