Results 91 to 100 of about 1,758,994 (174)

Antitumor mechanisms of combined gastrin-releasing peptide receptor and epidermal growth factor receptor targeting in head and neck cancer

, 2007
Head and neck squamous cell carcinoma (HNSCC) is characterized by epidermal growth factor receptor (EGFR) overexpression, where EGFR levels correlate with survival.
Bhola, NE, Mills, GB, Shin, D, Siwak, DR, Zhang, Q, Grandis, JR, Thomas, SM, Siegfried, JM, Gubish, CT, Lui, VWY   +9 more
core   +1 more source

Neonatal gastrin-releasing peptide receptor blockade reduces maternal odor preference in rats

, 2010
Alterations in attachment behavior might play a role in the dysfunction in social behavior displayed by autistic infants. Here we show that neonatal gastrin-releasing peptide receptor (GRPR) blockade induces a reduction in maternal odor preference, a ...
Dornelles, Arethuza da Silva, Schwartsmann, Gilberto, Alcalde, Luisa Azambuja, Halmenschlager, Luis Henrique, Lucion, Aldo Bolten, Torres, Juliana Presti, Roesler, Rafael, Schroder, Nadja, Garcia, Vanessa Athaíde   +8 more
core   +1 more source

Spinal k-Opioid Receptor Activation Attenuates Itch by Inhibiting Gastrin-releasing Peptide Receptor Function

, 2015
Chronic itch is a major unmet problem that cannot be treated with anti-histamines. Itch information is relayed from the skin to the brain via the spinal cord. Previous studies show that systemic activation of classically Gαi-coupled -opioid receptor (KOR)
Munanairi, Admire
core   +1 more source

[(99m)Tc]Demomedin C, a radioligand based on human gastrin releasing peptide(18-27): synthesis and preclinical evaluation in gastrin releasing peptide receptor-expressing models

, 2012
The synthesis and preclinical evaluation of [(99m)Tc]Demomedin C in GRPR-expressing models are reported. Demomedin C resulted by coupling a Boc-protected N(4)-chelator to neuromedin C (human GRP(18-27)), which, after (99m)Tc-labeling, afforded [(99m)Tc ...
Theodosia Maina, Maina, Theodosia, Cescato, Renzo, Beatrice Waser, Nock, Berthold A, Renzo Cescato, Waser, Beatrice, Eleni Ketani, Jean Claude Reubi, Berthold A. Nock, Reubi, Jean-Claude, Ketani, Eleni   +11 more
core   +1 more source

Gastrin-releasing peptide receptor (GRPR; GRP-R) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Involvement of Gastrin-Releasing Peptide (GRP) and Gastrin-Releasing Peptide Receptor (GRPR) in the mouse model of allergic rhinitis

Nihon Bika Gakkai Kaishi (Japanese Journal of Rhinology), 2017
Yokoi, Hidenori, Matsumoto, Yuma, Saito, Koichiro   +2 more
openaire   +2 more sources

Spinal cord interneurons expressing the gastrin-releasing peptide receptor convey itch through VGLUT2-mediated signaling

, 2018
Itch is a sensation that promotes the desire to scratch, which can be evoked by mechanical and chemical stimuli. In the spinal cord, neurons expressing the gastrin-releasing peptide receptor (GRPR) have been identified as specific mediators of itch ...
Blumel, E (15673412), Freitag, FB (15673409), Frank, MCM (15673418), Lau, J (15673415), Aresh, B (15673406), Lagerstrom, MC (15621506), Sharn Perry (14746618)   +6 more
core  

Gastrin-releasing peptide receptor: a promising new biomarker to identify cervical precursor lesions and cancer

Revista Brasileira de Ginecologia e Obstetrícia
Objective: This study aimed to verify the relation between gastrin-releasing peptide receptor (GRPR), oncogenic Human Papillomavirus (HPV) and cervical lesions severity.
Martina Lichtenfels, Rafaella Almeida Lima Nunes, Rossana Veronica Mendoza López, Camila Alves da Silva, Luiz Carlos Zeferino, Vanesca de Souza Lino, Adhemar Longatto-Filho, Louise De Brot, Silvia Helena Rabelo-Santos, Daniela Baumann Cornelio, Enrique Boccardo, Caroline Brunetto de Farias, Lara Termini   +12 more
doaj   +1 more source

Development of bispecific theranostic ligand targeting the prostate specific membrane antigen (PSMA) and gastrin releasing peptide (GRPR) receptor

Nuclear Medicine and Biology, 2021
Danai Bouzioti, Martin Schaefer, Ulrike Bauder-Wuest, Barbara Mavroidi, Evangelos Machairas, Antonis Kolokouris, Klaus Kopka, Penelope Bouziotis, Christos Liolios   +8 more
openaire   +1 more source

Evaluation of a new bombesin analogue labeled with 99mTc as potential targeted tumor scintigraphic agent

Research in Molecular Medicine, 2013
Background: Bombesin shows high affinity for Gastrin-releasing peptide (GRP) receptors which over expressed on the cell surfaces of several human tumors particularly in prostate and breast cancers.
Nourollah sadeghzadeh, Mostafa Erfani, Mahmoud Omidi   +2 more
doaj