Results 41 to 50 of about 55,603 (271)

Low serum gastrin associated with ER+ breast cancer development via inactivation of CCKBR/ERK/P65 signaling

BMC Cancer, 2018
Background Gastrin is an important gastrointestinal hormone produced primarily by G-cells in the antrum of the stomach. It normally regulates gastric acid secretion and is implicated in a number of human disease states, but how its function affects ...
Li-Li Meng, Jing-Long Wang, Shu-Ping Xu, Li-Dong Zu, Zhao-Wen Yan, Jian-Bing Zhang, Ya-Qin Han, Guo-Hui Fu   +7 more
doaj   +1 more source

The gastric acid pocket is attenuated in H. pylori infected subjects [PDF]

, 2016
Objective Gastric acid secretory capacity in different anatomical regions, including the postprandial acid pocket, was assessed in Helicobacter pylori positive and negative volunteers in a Western population. Design We studied 31 H.
Ballantyne, Stuart A., Derakhshan, Mohammad H., Going, James J., McColl, Kenneth E.L., Mitchell, David R., Orange, Clare, Wirz, Angela A.   +6 more
core   +1 more source

Islets from human donors with higher but not lower hemoglobin A1c levels respond to gastrin treatment in vitro.

PLoS ONE, 2019
Gastrin is a peptide hormone, which in combination with other factors such as TGFα, EGF or GLP-1, is capable of increasing beta cell mass and lowering blood glucose levels in adult diabetic mice.
Ayelet Lenz, Gal Lenz, Hsun Teresa Ku, Kevin Ferreri, Fouad Kandeel   +4 more
doaj   +1 more source

Association of Gastric Myoelectrical Activity With Ghrelin, Gastrin, and Irisin in Adults With Metabolically Healthy and Unhealthy Obesity

Frontiers in Physiology, 2022
Background and Objective: Functional disturbances of gastric myoelectrical activity (GMA) might exist in obesity. However, studies on its association with the gastric hormones in obesity phenotypes are lacking.
Mahmoud M. A. Abulmeaty, Mahmoud M. A. Abulmeaty, Dara Aldisi, Ghadeer S. Aljuraiban, Ali Almajwal, Eman El Shorbagy, Yara Almuhtadi, Batool Albaran, Zaid Aldossari, Thamer Alsager, Suhail Razak, Mohammed Berika, Mohamed Al Zaben   +12 more
doaj   +1 more source

Effect of gastric acid-suppressive therapy and biological variation of serum gastrin concentrations in dogs with chronic enteropathies

BMC Veterinary Research, 2017
Background Serum gastrin concentration can help diagnose gastrinomas in dogs if >3–10× the upper reference limit (URL), but antisecretory therapy and other conditions can also cause hypergastrinemia.
Romy M. Heilmann, Nora Berghoff, Niels Grützner, Nolie K. Parnell, Jan S. Suchodolski, Jörg M. Steiner   +5 more
doaj   +1 more source

Effect of Dexmedetomidine-Assisted Intravenous Anesthesia on Gastrointestinal Motility in Colon Cancer Patients After Open Colectomy

Frontiers in Surgery, 2022
BackgroundTo explore the effect of dexmedetomidine (Dex)-assisted intravenous anesthesia on gastrointestinal motility in patients with colon cancer (CC) after open colectomy.MethodsA total of 102 patients with CC, undergoing open colectomy in our ...
Chaopeng Ou, Shiyang Kang, Ruifeng Xue, Jielan Lai, Yingjun Zhang   +4 more
doaj   +1 more source

Case report: Fundic gland polyps caused by long-term omeprazole use in a Maltese dog

Frontiers in Veterinary Science, 2023
Long-term use of proton-pump inhibitors can induce fundic gland polyps in the human stomach. However, this phenomenon has not been described in the veterinary literature.
Haemin Lee, Sanggu Kim, Dohee Lee, Yeon Chae, Taesik Yun, Mhan-Pyo Yang, Byeong-Teck Kang, Soochong Kim, Hakhyun Kim   +8 more
doaj   +1 more source

Diffuse somatostatin-immunoreactive D-cell hyperplasia in the stomach and duodenum [PDF]

, 1986
This paper presents the first case of extensive, diffuse, somatostatin- immunoreactive D-cell hyperplasia in the human stomach and duodenum. It occurred in a 37-yr-old woman, who showed clinical signs of dwarfism, obesity, dryness of the mouth, and ...
Eisenmenger, Wolfgang, Holle, G. E., Pradayrol, L., Riedel, J., Spann, W.   +4 more
core   +1 more source

Effect of N-Terminal Peptide Modifications on In Vitro and In Vivo Properties of ¹⁷⁷Lu-Labeled Peptide Analogs Targeting CCK2R

Pharmaceutics, 2023
The therapeutic potential of minigastrin (MG) analogs for the treatment of cholecystokinin-2 receptor (CCK2R)-expressing cancers is limited by poor in vivo stability or unfavorable accumulation in non-target tissues. Increased stability against metabolic
Anton Amadeus Hörmann, Maximilian Klingler, Christine Rangger, Christian Mair, Lieke Joosten, Gerben M. Franssen, Peter Laverman, Elisabeth von Guggenberg   +7 more
doaj   +1 more source

Analysis of cell hyperplasia and parietal cell dysfunction induced by Ostertagia ostertagi infection [PDF]

, 2013
Infections in cattle with the gastric nematode Ostertagia ostertagi are associated with decreased acid secretion and profound physio-morphological changes of the gastric mucosa.
Chiers, Koen, Claerebout, Edwin, Geldhof, Peter, Goddeeris, Bruno, Mihi, Belgacem, Rinaldi, Manuela, Van Coppernolle, Stefanie, Van Den Broeck, Wim, Van Meulder, Frederik, Vercruysse, Jozef   +9 more
core   +2 more sources