Results 191 to 200 of about 160,008 (264)

Mechanisms of SCN2A loss of function do not predict presence or phenotype of epilepsy

Epilepsia, EarlyView.
Abstract Objective SCN2A loss‐of‐function (LoF) variants are associated with epilepsy (onset age ≥ 3 months), intellectual disability (ID), and autism spectrum disorder (ASD). Despite numerous identified variants and the description of phenotypic subgroups, relationships between Nav1.2 channel dysfunction and clinical phenotypes remain unclear.
Marsha Tan, Beatrice Southby Goad, Meagan Allen, Jill Rodda, Kay L. Richards, Simone L. Ardern‐Holmes, Daniel Bamborschke, Daniel Fritzen, Inna Hughes, Kate Riney, Ana Roche Martinez, Angelo Russo, Adriane Sinclair, Stefano Sartori, Marina Trivisano, Angela De Dominicis, Nicola Specchio, Rikke S. Møller, Ingrid E. Scheffer, Walid Fazeli, Markus Wolff, Steven Petrou, Katherine B. Howell, Géza Berecki   +23 more
wiley   +1 more source

Relevance of Autophagy Induction by Gastrointestinal Hormones: Focus on the Incretin-Based Drug Target and Glucagon. [PDF]

Front Pharmacol, 2019
Kanasaki K, Kawakita E, Koya D.
europepmc   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Highly purified cannabidiol (CBD) in CDKL5 deficiency disorder (CDD): Open‐label prospective study

Epilepsia Open, EarlyView.
Abstract Objective CDKL5 deficiency disorder (CDD) is an early‐onset developmental and epileptic encephalopathy characterized by frequent drug‐resistant seizures, cerebral visual impairment, motor dysfunction, and sleep and gastrointestinal disturbances.
Marco Perulli, Alessia De Gioia, Federica Ruggiero, Federica Ascione, Chiara Porto, Elisa Musto, Valentina Massaroni, Maria Picilli, Maria Luigia Gambardella, Michela Quintiliani, Ilaria Contaldo, Chiara Veredice, Domenica Immacolata Battaglia   +12 more
wiley   +1 more source

Home-Based Transcutaneous Neuromodulation Improved Constipation via Modulating Gastrointestinal Hormones and Bile Acids. [PDF]

Evid Based Complement Alternat Med, 2018
Ge Z, Duan Z, Yang H, Zhang S, Zhang S, Wang L, Yang D, Sun X, Zhang Z, Su L, Zhu H, Zhou D, Liu B, Shi H, Yu J, Yang H, Chang Q, Zhang N, Wu D, Chen JDZ.   +19 more
europepmc   +1 more source

The effect of resveratrol on cognitive performance: a systematic literature review and meta-analysis [PDF]

, 2017
Annois, Brigitte, Cutajar, Jennifer, Itsiopoulos, Catherine, Kelly, Jaimon T, Marshall, Skye, Marx, Wolfgang, Pipingas, Andrew, Tierney, Audrey C   +7 more
core  

Clinician Practices in Determining Expected Body Weights Across Eating Disorders: A Mixed Methods Study

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Eating disorder (ED) treatment often involves establishing expected body weights (EBWs). While individualised approaches are commonly used, whether and how EBWs are set across EDs, clinician perspectives on different approaches, and clinician training in this practice remain poorly understood.
Agatha A. Laboe, Molly F. Steinhoff, Siena S. Vendlinski, Anna Kreynin, Sarah Johnson‐Munguia, Ava Heyrman, Sophia Kreckler, Caitlyn Ruud, Katherine Schaumberg   +8 more
wiley   +1 more source

The effect of the intracervical administration of follicle stimulating hormone or luteinizing hormone on the levels of hyaluronan, COX2 and COX2 mRNA in the cervix of the nonpregnant ewe [PDF]

, 2016
Khalid, M, Leethongdee, S, Scaramuzzi, R J   +2 more
core   +1 more source

Temporal Trends in the Epidemiology of Eating Disorders Between 2000 and 2022: A Danish Register Study of Their Incidence and Comorbidities

European Eating Disorders Review, EarlyView.
ABSTRACT Background Eating disorders are debilitating illnesses that often co‐occur with other psychiatric disorders and somatic diseases. Evidence indicates that the incidence of eating disorders has been increasing. We first examine the landscape of EDs over time, including the COVID‐19 period, via assessing the incidence of anorexia nervosa (AN ...
Nadia Micali, Helena L. Davies, Heidi Jeannet Graff, Laust H. Mortensen, Emilie R. Hegelund   +4 more
wiley   +1 more source

High‐Caloric Realimentation and Mental and Physical Well‐Being in Patients With Extreme Anorexia Nervosa. A Prospective Study

European Eating Disorders Review, EarlyView.
ABSTRACT Objective While high caloric realimentation (HCR) is increasingly recommended for quick weight restoration of patients with anorexia nervosa (AN), the development of AN‐specific psychopathology and somatic symptoms during HCR have so far insufficiently been studied.
Ulrich Voderholzer, Juliane Silbernagl, Verena Haas, Ulrich Cuntz, Silke Naab, Norbert Quadflieg   +5 more
wiley   +1 more source